Glucose

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Nursing

Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects


Responsibilities
Generic Name: Pharmacologic Class: Pharmacodynamics General Indication: Except under special Mild vomiting may Before Drug
Oral Rehydration Salts Electrolyte Solutions or Mechanism of  used for fluid or circumstances, this occur when oral Administration
Action: electrolyte medication should not be therapy has begun, but - Drug should be
Trade/Brand Name: Therapeutic Class: The reconstituted depletion used when the following therapy should be stored away from
Oresol, Fruitrofill Fluid and Electrolyte solution contains a  Maintenance of medical problems exist: continued with moisture. Packaging
Replacement mixture of sodium and water and o Anuria frequent, small should be in sachets,
Minimum dose: potassium salts along electrolytes, o Oliguria amounts of solution preferably made of
2, 200 ml with glucose, which which is followed o Dehydration, administered slowly. aluminum foil, which
facilitates the by the corrective severe, with Rarely, symptoms of is sufficient for a
Maximum dose: absorption of sodium parenteral symptoms of hypernatremia single dose or a day’s
4, 400 ml and potassium from therapy for severe shock (oral (dizziness, fast treatment.
the intestine. Water is diarrhea rehydration is heartbeat, high blood - Dosage of the oral
Patient’s Dose: drawn from the bowel  Replaces the mild too slow; rapid pressure, irritability, rehydration should be
75 mL per kg of by the osmotic effect. to moderate fluid intravenous muscle twitching, based on the
weight As well as “drying up” losses when food therapy is restlessness, and individual’s body-
the stools, the and liquid intake necessary) seizures, swelling of weight and the severity
Route: dehydration and loss of is discontinued. o Glucose feet or lower legs, or of the condition.
PO electrolytes caused by  Minimizing malabsorption weakness) may be - Do not use the
the diarrhea is chronic fatigue, o Inability to drink experienced. powder if it has turned
Frequency: corrected by the water muscle cramps, or vomiting, into a yellow-brownish
To be consumed in 4 and electrolytes or heat severe and sticky substance.
hours absorbed. prostration sustained
because of o Intestinal During Drug
Availability: Pharmacokinetics: excessive obstruction Administration
Oral powders Glucose perspiration - Oral rehydration salts
-glucose is completely should only be
Content: absorbed by a sodium Patient’s Indication: reconstituted with
Sodium Chloride- 320 dependent uptake Treatment for patient’s water (Fresh drinking
mg mechanism moderate dehydration as water is appropriate) at
Potassium Chloride- exhibiting saturation a fluid and electrolyte the given volume
300 mg kinetic replacement after active stated.
Sodium Bicarbonate- -Blood levels return to fluid loss through - Stir until completely
300 mg normal within two vomiting and to prevent dissolved.
Anhydrous glucose- hours of ingestion. further dehydration - Solution should not
7.28 g be boiled after it is
Potassium Chloride prepared.
-No specific control - Do not keep the
mechanisms limit solution for more than
absorption of one hour at room
potassium, which is temperature. If kept in
usually complete. a fridge, the drug can
be kept for 24 hours.
Potassium
-excreted largely by After Drug
the kidneys, though Administration
10% is excreted by the - Oral Rehydration
colonic mucosa. Solution should be
discarded after 24
Sodium Bicarbonate hours of reconstitution.
-Readily absorbed
from the
gastrointestinal tract.
- Gut absorption,
particularly in the
jejunum is enhanced
by the addition of
glucose.
- Excretion of sodium
in the urine will match
intake.

References:

Vallerand, A., Sanoski, C., & Deglin, J. (2017). Drug Guide for Nurses. 15th Ed. FA Davis Company: Philadelphia

Schull, P. D. (2013). McGraw-Hill nurses drug handbook. New York: McGraw-Hill Medical.

JONES & BARTLETT LEARNING. (2018). Nurses Drug Handbook. SUDBURY.

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