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    Metronidazole

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    Martha Glorie Manalo Wallis
    1. Metronidazole is an antibiotic used to treat various infections caused by bacteria and parasites. It works by disrupting the DNA of the infecting organisms. 2. Common side effects include nausea, vomiting, and neurological symptoms like headache and dizziness. When taken orally, it can cause an interaction with alcohol resulting in nausea and flushing. 3. Nurses monitor patients for side effects and drug interactions, educate them about completing treatment and avoiding alcohol during therapy, and check stool samples in cases of parasitic infection.

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    Metronidazole

    Uploaded by

    Martha Glorie Manalo Wallis
    408 views2 pages
    1. Metronidazole is an antibiotic used to treat various infections caused by bacteria and parasites. It works by disrupting the DNA of the infecting organisms. 2. Common side effects include nausea, vomiting, and neurological symptoms like headache and dizziness. When taken orally, it can cause an interaction with alcohol resulting in nausea and flushing. 3. Nurses monitor patients for side effects and drug interactions, educate them about completing treatment and avoiding alcohol during therapy, and check stool samples in cases of parasitic infection.

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    1. Metronidazole is an antibiotic used to treat various infections caused by bacteria and parasites. It works by disrupting the DNA of the infecting organisms. 2. Common side effects include nausea, vomiting, and neurological symptoms like headache and dizziness. When taken orally, it can cause an interaction with alcohol resulting in nausea and flushing. 3. Nurses monitor patients for side effects and drug interactions, educate them about completing treatment and avoiding alcohol during therapy, and check stool samples in cases of parasitic infection.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    408 views2 pages

    Metronidazole

    Uploaded by

    Martha Glorie Manalo Wallis
    1. Metronidazole is an antibiotic used to treat various infections caused by bacteria and parasites. It works by disrupting the DNA of the infecting organisms. 2. Common side effects include nausea, vomiting, and neurological symptoms like headache and dizziness. When taken orally, it can cause an interaction with alcohol resulting in nausea and flushing. 3. Nurses monitor patients for side effects and drug interactions, educate them about completing treatment and avoiding alcohol during therapy, and check stool samples in cases of parasitic infection.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 2

    MECHANISM OF INDICATION

    DRUG NAME ADVERSE EFFECT NURSING RESPONSIBILITIES


    ACTION CONTRAINDICATION

    GENERIC: Diffuses into INDICATIONS: Common Side Effect: Dx:


    organism, interacting
    Metronidazole with DNA causing a 1. CNS infections such as meningitis, CNS: peripheral neuropathy, a) Monitor daily pattern of bowel
    brain abscess, subdural empyema headache, sleeplessness, activity, stool consistency.
    loss of helical DNA and septic thrombophlebitis
    structure and strand dizziness, ataxia, paresthesia b) Monitor I&O, assess for urinary
    2. Gynecological Infections:
    BRAND: breakage, inhibiting problems.
    Endometrics, tubo-ovarian abscess,
    GI: nausea, gastrointestinal c) Be alert to neurologic symptoms
    protein synthesis. vaginal cuff infections, pelvic
    Erzol pain (dizziness, paresthesia of
    Therapeutic Effect: abscesses, Bartholin’s abscess,
    Produces vaginal salphingitis and post extremities).
    abortion sepsis. Systemic: Anorexia, dry d) Assess for rash, urticaria.
    bactericidal,
    THERAPEUTIC CLASS: 3. Chest Infections: Aspiration mouth, metallic taste. e) Monitor for onset of
    antiprotozoal, pneumonitis, lung abscesses,
    amebicidal, superinfection (ulceration/change
    Nitroimidazole derivative necrotizing pneumonia, Vaginal: Symptomatic
    trichomonacidal of oral mucosa, furry tongue,
    emphysema and bronchitis. cervicitis/vaginitis, abdominal
    effects. Produces 4. Intra-abdominal Infections: vaginal discharge, genital/anal
    cramps, uterine pain. pruritus).
    antiinflammatory, Peritonitis, intra-abdominal, and
    PHARMACOLOGIC: liver abscesses, post operative
    immunosuppressive Tx:
    abdominal and wound infections Occasional:
    Antiprotozoal effects when applied
    and appendicitis.
    topically. a) Obtain baseline CBC, LFT.
    5. Urinary Tract Infections: Peri- Systemic: Diarrhea,
    urethral cellulitis abscess or b) Question for history of
    Source: constipation, vomiting, hypersensitivity to
    DOSAGE: 5mg/mL gangrene, chronic prostatic abscess,
    renal abscess, perirenal abscess and dizziness, erythematous rash, metronidazole, other
    Saunders-Nursing- urticaria, reddish-brown urine.
    Adult: 500 mg testicular abscess. nitroimidazole derivatives
    Drug-Handbook-
    Children: 7.5 mg/kg 6. Other Indications: Endocarditis, (and parabens with topical).
    2021-1st-Edition bacteremia,osteomyelitis Topical: Transient erythema,
    mild dryness, burning, c) Obtain specimens for
    ROUTE: IV, PO speticemia, bone and joint
    irritation, stinging, tearing diagnostic tests, cultures
    infections, prophylaxis in chronic
    surgery. when applied too close to eyes. before giving first dose
    (therapy may begin before
    Vaginal: Vaginal perineal, results are known).
    CONTRAINDICATIONS: vulvar itching; vulvar swelling d) Administer drug with meals to
    1. History of hypersensitivity to minimize GI distress
    Metronidazole Rare: e) Reduce dosage in hepatic
    disease
    DRUG TO DRUG INTERACTIONS: Mild, transient leukopenia;
    thrombophlebitis with IV Edx:
     Intravenous administration of therapy
    Metronidazole intravenous a) Advise pt that urine may be red-
    infusion and other medications brown or dark.
    are not recommended. b) Instruct pt to avoid alcohol,
     Alcohol may cause alcohol-containing preparations
    disulfiramtype reaction (e.g., (cough syrups, elixirs) for at least
    abdominal cramps, nausea, 48 hrs after last dose.
    vomiting, headache, psychotic c) Instruct pt to avoid tasks that
    reactions). require alertness, motor skills
     Disulfiram may increase risk of until response to drug is
    toxicity. established.
     May increase effects of oral d) Educate pt that if taking
    anticoagulants (e.g., warfarin). metroNIDAZOLE for
    trichomoniasis, refrain from
    DRUG TO FOOD INTERACTIONS: sexual intercourse until full
    treatment is completed.
    None known. e) Educate pt that for amebiasis,
    frequent stool specimen checks
    will be necessary.

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