Applications of Colloids

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COLLOIDS

Dr. Vijay
Dept. of Pharm. Sciences
HNB Garhwal University,
Srinagar, Uttarakhand

Dr. Vijay, DOPS, HNB Garhwal University 1


Applications of Colloids
Colloids have varied applications. Some of them include:
• Medicines: Medicines in colloidal form are easily absorbed by the body tissues and hence
are more effective.
• Cleansing action of soap: Soap solution is colloidal in nature. It removes the dirt particles
either by adsorption or by emulsifying the greasy matter sticking to the cloth
• Purification of water: The precipitation of colloidal impurities present in water can be
done by adding certain electrolytes like alum etc. The negatively charged colloidal
particles of impurities get neutralized by the Al3+ ions and settle down and pure water
can be decanted off.
• Rubber industry: Latex is a colloidal solution of negatively charged rubber particles. From
latex, rubber can be obtained by coagulation. Rubber plated articles are prepared by
depositing negatively charged rubber particles over the article to be rubber plated by
making that article an anode in a rubber plating bath
Dr. Vijay, DOPS, HNB Garhwal University 2
• Colloids formulation exhibits unusal or increased therapeutic properties
• Colloidal silver chloride, silver iodide and silver protein are effective germicide and do not
cause the irritation that is the characteristic of ionic silver salts
• Coarsely powdered sulphur is poorly absorbed when administered orally but the coarser
form of sulphur is highly absorbed. Sometime deaths also reported
• Colloidal copper is used in the treatment of cancer
• Colloidal gold is used as a diagnostic agent for Paresis
• Colloidal mercury is used in the treatment of Syphilis
• Proteins are natural colloids and are found in the body as components of muscle, bone and
skin. They bind with certain drugs and change the pharmacological activity of drugs
• Naturally occurring plant macromolecules like Starch and Cellulose exist in colloidal state and
are used as pharmaceutical adjuncts or additives
• Hydroxyethyl cellulose is used as a Plasma Substitute
• Colloidal electrolytes are sometimes used to increase solubility, stability and taste of certain
compounds in aqueous and oily preparations
Dr. Vijay, DOPS, HNB Garhwal University 3
• Colloids are extensively used for modifying the properties of pharmaceutical agents:
• The most common property that is affected is the solubility of a drug
• However, colloidal forms of many drugs exhibit substantially different properties when
compared with traditional forms of these drugs
Colloids are used as drug delivery systems which includes
• Hydrogels
• Microspheres
• Microemulsions
• Liposomes
• Micelles
• Nanoparticles
• Nanocrystals
Dr. Vijay, DOPS, HNB Garhwal University 4
References
• Martin’s Physical pharmacy and Pharmaceutical Sciences (5th edition)
• Industrial Pharmacy by Lachman
• www. Google.com
• Wikipedia
• RPS

Dr. Vijay, DOPS, HNB Garhwal University 5

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