A. Prof. DR Ruzanna PHD, DM, MD, MSC
A. Prof. DR Ruzanna PHD, DM, MD, MSC
A. Prof. DR Ruzanna PHD, DM, MD, MSC
Dr Ruzanna
PhD, DM, MD, MSc.
Types of Muscle Tissue
Skeletal
Cardiac
Smooth
Similarities…
cytoplasm peripheral
(=sarcoplasm) multiple nuclei cell membrane
(=sarcolemma)
myofibrils
cross-striations
(alternating light
and dark bands)
Characteristic
banding pattern
due to the
arrangement of
the myofilaments
MYOFIBRIL
myofilaments inside A single
the myofibril do not SARCOMERE
myofibril
extend the entire length
of the MYOFIBRILS but
are arranged in repeating
Thin actin Thick myosin
units called SARCOMERES
filament filament with
Z LINE cross bridges
Z LINE
SARCOMERE Myofilaments
Parts of a Muscle
Connective Tissue Sheaths
▪ Connective Tissue of a Muscle
▪ Epimysium - Dense regular c.t. that surrounds entire muscle
▪ Separates muscle from surrounding tissues and organs.
▪ Perimysium -Fibrous c. t. that surrounds a group of muscle
fibers called a fascicle
▪ Contains b.v and nerves.
▪ Endomysium -Loose connective tissue that surrounds individual
muscle fibers.
▪ Also contains b.v., nerves.
Epimysium is a dense regular c.t. surrounding entire muscle
Separates muscle from surrounding tissues and organs.
Perimysium is a fibrous c.t. surrounding a group of muscle fibers
called a fascicle Skeletal muscle
Contains b.v and nerves.
Epimysium:
surrounds
whole muscle
Endomysium is a loose
connective tissue surrounding
each muscle fiber
Perimysium is
around fascicle
TENDON
EPIMYSIUM
ENDOMYSIUM
BONE
MUSCLE FIBER
PERIMYSIUM
ENDOMYSIUM
FASCICLE
Skeletal Muscle Structure
➢ Composed of muscle cells (fibers), connective tissue, blood vessels,
nerves.
➢ Fibers are long, cylindrical, and multinucleated.
➢ Develop from myoblasts
➢ Striated appearance
➢ Nuclei are peripherally located under the
sarcolemma
➢ Function
➢ Voluntary movement
➢ Location
➢ Attach to the skeleton
Sarcoplasm
In addition to the usual
organelles, contains
unusually large amounts
of glycosomes –
granules of stored
glycogen
myoglobin- red
pigment that stores
oxygen
Cardiac muscle has several distinct
characteristics:
1. Cardiac muscle is striated, like skeletal muscle.
2. Cardiac muscle consists of distinct, individual cells, unlike
skeletal muscle, is not called fibers (which consists of long,
multinucleate fibers).
3. Cardiac muscle cells are attached end-to-end by specialized
junctions called intercalated discs.
4.Each end of a
cardiac muscle cell
may attach to two or
more other cells, so
that the fibrous
structure of cardiac
muscle appears to be
branched (unlike
skeletal muscle, where
each fiber is a single,
discrete unit).