Genetics Problem
Genetics Problem
Genetics Problem
:
Genetics – Solving problems
Date :
2. A woman has a rare abnormality of the eyelids called ptosis, which makes it
impossible for her to open her eyes completely. The condition has been found to
depend on a single dominant gene P. The woman’s father had ptosis, but her mother
had normal eyelids. Her father’s mother had normal eyelids. (a) What are the probable
genotypes of the woman, her father and mother? (b) What proportion of her children
will be expected to have ptosis if she marries a man with normal eyelids?
3. In shorthorn cattle, the gene(R) for red coat is not dominant over that for white
(R’). The heterozygous combination (RR’) produces roan. A breeder has white, red
and roan cows and bulls. What phenotypes might be expected from the following
matings, and in what proportions? a) red x red, b) red x roan, c) red x white, d) roan x
roan, e) roan x white, f) white x white.
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6. The shape and color of radishes are controlled by two independent pairs of alleles
that show no dominance; each genotype is distinguishable phenotypically. The colour
may be red RR, purple RR’ or white R’R’ and the shape may be long LL, oval L’L or
round L’L’. Using the Punnett square method, diagram a cross between red, long and
white, round radishes and summarize the F 2 results under the headings phenotypes,
genotypes, genotypic frequency and phenotypic frequency.
8. In the F2 generation of a certain tomato experiment 3629 fruits were red and 1175
were yellow. A 3:1 ratio was expected. a) Are the discrepancies between the observed
and expected ratios significant? b) In the same experiment, 671 plants with green
foliage and 569 with yellow were counted. This was a backcross and the hypothetical
ratio was 1:1. Test the chi-square and explain? (Chi-square at 0.05% at 1 df is 3.841)
9. What is the probability in families of six of a) one boy and five girls, b) three boys
and three girls and c) all six girls?
10. In humans, a series of alleles has been associated with ABO blood types as
follows. IA, A type, IB, B type, IO, O type. IA and IB are codominant; IAIB heterozygotes
have AB blood type. IO is recessive to both IA and IB. What phenotypes and ratios
might be expected from the following matings. a) I AIA x IBIB, b) IAIB x IOIO, c) IAIO x
IBIO and d) IAIO x IOIO.