Genetics Problem

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Ex. No.

:
Genetics – Solving problems
Date :

1. In pigeons, the checkered pattern is dependent on a dominant gene C and a plain


exterior on the recessive allele c. Red colour is controlled by a dominant gene B and
brown by recessive allele b. Diagram completely a cross between homozygous
checkered red birds and plain brown birds. Summarize the F2 results.

2. A woman has a rare abnormality of the eyelids called ptosis, which makes it
impossible for her to open her eyes completely. The condition has been found to
depend on a single dominant gene P. The woman’s father had ptosis, but her mother
had normal eyelids. Her father’s mother had normal eyelids. (a) What are the probable
genotypes of the woman, her father and mother? (b) What proportion of her children
will be expected to have ptosis if she marries a man with normal eyelids?

3. In shorthorn cattle, the gene(R) for red coat is not dominant over that for white
(R’). The heterozygous combination (RR’) produces roan. A breeder has white, red
and roan cows and bulls. What phenotypes might be expected from the following
matings, and in what proportions? a) red x red, b) red x roan, c) red x white, d) roan x
roan, e) roan x white, f) white x white.

4. Albinism in humans is controlled by a recessive gene c. From marriages between


normally pigmented people known to be carriers Cc and albinos cc: a) What
proportion of children would be expected to be albinos? b) What is the chance in a
family of three that one would be normal and two albinos?

5. In Drosophila, a dominant gene D for a phenotype called ‘dichaete’ alters the


bristles and also makes the wings remain extended from the body while the fly is at
rest. It is homozygous lethal. a) Diagram a cross between two dichaete Dd flies and
summarize the expected results. b) Diagram a cross between dichaete and wild type
and summarize the expected results.

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6. The shape and color of radishes are controlled by two independent pairs of alleles
that show no dominance; each genotype is distinguishable phenotypically. The colour
may be red RR, purple RR’ or white R’R’ and the shape may be long LL, oval L’L or
round L’L’. Using the Punnett square method, diagram a cross between red, long and
white, round radishes and summarize the F 2 results under the headings phenotypes,
genotypes, genotypic frequency and phenotypic frequency.

7. White fruit colour in summer squash is dependent on a dominant allele W and


coloured fruit on the recessive allele w, In the presence of ww and a dominant gene G,
the colour is yellow, but when G is absent i.e., gg, the colour is green. Give the F 2
phenotypes and proportions that are expected from crossing a white fruited plant with
a green fruited plant.

8. In the F2 generation of a certain tomato experiment 3629 fruits were red and 1175
were yellow. A 3:1 ratio was expected. a) Are the discrepancies between the observed
and expected ratios significant? b) In the same experiment, 671 plants with green
foliage and 569 with yellow were counted. This was a backcross and the hypothetical
ratio was 1:1. Test the chi-square and explain? (Chi-square at 0.05% at 1 df is 3.841)

9. What is the probability in families of six of a) one boy and five girls, b) three boys
and three girls and c) all six girls?

10. In humans, a series of alleles has been associated with ABO blood types as
follows. IA, A type, IB, B type, IO, O type. IA and IB are codominant; IAIB heterozygotes
have AB blood type. IO is recessive to both IA and IB. What phenotypes and ratios
might be expected from the following matings. a) I AIA x IBIB, b) IAIB x IOIO, c) IAIO x
IBIO and d) IAIO x IOIO.

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