University of Hargeisa GIT Pharmacology Review Questions: Name:aniisa Muse Ahmed Faculty:midwifery ID:1716642 Class:3A

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University Of Hargeisa

GIT Pharmacology Review Questions


Name:aniisa muse ahmed
Faculty:midwifery
ID:1716642
Class:3A
1. Which of the following antacids cause Milk alkali syndrome?
a. Aluminum hydroxide gel (Al(OH)3,
b. Magnesium trisilicate,(MgS2O3)
c. Mg hydroxide(Mg(OH)2,)
d. Calcium carbonate(CaCO23)
2. Which of the following is very effective antacid but causes systemic
alkalosis?
a. Aluminum hydroxide gel (Al(OH)3,
b. Magnesium trisilicate,(MgS2O3)
c. Mg hydroxide(Mg(OH)2,)
d. Calcium carbonate(CaCO3)
e. Sodium bicarbonate

3. An anti-ulcer drug which has the side-effects of urinary retention, blurred


vision, dry mouth may block to which receptor?

a. M3-receptor

b. G-receptor

c. H2 receptor

d. CCK-receptor

4. A penicillin-allergic H. pylori-positive 36-year-old lady with epigastric pain


and a duodenal ulcer was admitted to the Emergency Department . which
drug treatment regimen would you prefer to treat her PUD?
a. bismuth subsalicylate + metronidazole + tetracycline

b. omeprazole + metronidazole + clarithromycin

c. omeprazole + Amoxicillin + clarithromycin

d. ranitidine bismuth citrate(RBC) + clarithromycin

5. 35 year old patient who is on carbamazepine for Bipolar disorder was also
prescribed omeprazole for PUD. What would recommend?

a. Reduce the dose of carbamazepine

b. Increase the dose of carbamazepine

c. Stop carbamazepine while you are taking omeprazole

d. Take both drugs at usual doses.

6. Omeprazole and cimetidine are two anti-secretory drugs with least drug
interaction (least enzyme inhibitors)?

a. True

b. False

7. The most serious side-effects of cimetidine are hypotension and


bradycardia.

a. True

b. False

8. Which of the following H2 receptors antagonists have equal efficacy if


taken oral route or intravenous route?

a. Cimetidine

b. Nizatidine

c. Ranitidine
d. Famotidine

9. a 70-year-old woman with rheumatoid arthritis is now taking


Endomethacine and prednisolone for his arthritis. YOU think that he is at
risk of developing an NSAID-induced ulcer or ulcer-related complication .
what would you give to prevent it ?

a. Misoprostol 800 µg daily.

b. famotidine 40 mg twice daily.

c. omeprazole 40 mg twice daily.

d. Pantoprazole 40mg dail.

e. Non of the above

10. Best protocol for eradication of H. pylori/treatment of peptic ulcer disease:

a. Lansoprazole + Amoxicillin + Clarithromycin

b. Omeprazol+metronidazol+clarithromycin

c. bismuth monotherapy
d. all of the above.
11.Stimulation of H2, M3 and Gastrin and EP2 receptors causes increase HCL
a. True
b. False

12.Which of the following drugs have anti-androgenic effect and


Gynecomastia, Galactorrhea and Impotence?
a. Cimetidine
b. Methyl dopa
c. Spironalactone
d. All of the above
13. This drug has cytoprotective effect; binds protein in ulcer base, increase
PGs and also has ant-H.pylori effect.
a. Sucralfate
b. Colloidal Bismuth
c. Misoprostol
d. PPI
14.Which of the following agents cause cause phosphate depletion?

a. Aluminum hydroxide gel (Al(OH)3,


b. Magnesium trisilicate,(MgS2O3)
c. Mg hydroxide(Mg(OH)2,)
d. Calcium carbonate(CaCO3)
e. Sodium bicarbonate
15. Misoprostol is contraindicated in pregnant women because it is terotagenic
to the fetus
a. True
b. False
16.Omeprazole is not known to be harm full in pregnancy while cimetidine is
advised not to use during pregnancy unless essential?
a. True
b. False
17.Maalox syrup is a Mixtures of aluminium hydroxide and magnesium
hydroxide so usually it causes both diarrhea and constipation
a. True
b. False

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