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    Azathioprine - Frequent:: Anti-Inflammatory Immunosuppressive That Can Decrease Joint Damage and Disability

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    Jordz Placi
    This document summarizes key information about the mechanism of action, indications, contraindications, common side effects, and nursing considerations for azathioprine, acetaminophen, and corticosteroids. Azathioprine works by antagonizing purine metabolism and inhibiting DNA, protein, and RNA synthesis to produce its anti-inflammatory and immunosuppressive effects. Common side effects include nausea, vomiting, and anorexia. Nursing considerations include assessing for allergies and monitoring for gastrointestinal disturbances. Acetaminophen provides relief of mild to moderate pain by inhibiting prostaglandin synthesis in the central nervous system and blocking pain impulses peripherally. Common side effects are rare but include hypersensitivity reactions.

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    Azathioprine - Frequent:: Anti-Inflammatory Immunosuppressive That Can Decrease Joint Damage and Disability

    Uploaded by

    Jordz Placi
    47 views3 pages
    This document summarizes key information about the mechanism of action, indications, contraindications, common side effects, and nursing considerations for azathioprine, acetaminophen, and corticosteroids. Azathioprine works by antagonizing purine metabolism and inhibiting DNA, protein, and RNA synthesis to produce its anti-inflammatory and immunosuppressive effects. Common side effects include nausea, vomiting, and anorexia. Nursing considerations include assessing for allergies and monitoring for gastrointestinal disturbances. Acetaminophen provides relief of mild to moderate pain by inhibiting prostaglandin synthesis in the central nervous system and blocking pain impulses peripherally. Common side effects are rare but include hypersensitivity reactions.

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    SLE-DRUG-STUDY-LASCAÑAS

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    This document summarizes key information about the mechanism of action, indications, contraindications, common side effects, and nursing considerations for azathioprine, acetaminophen, and corticosteroids. Azathioprine works by antagonizing purine metabolism and inhibiting DNA, protein, and RNA synthesis to produce its anti-inflammatory and immunosuppressive effects. Common side effects include nausea, vomiting, and anorexia. Nursing considerations include assessing for allergies and monitoring for gastrointestinal disturbances. Acetaminophen provides relief of mild to moderate pain by inhibiting prostaglandin synthesis in the central nervous system and blocking pain impulses peripherally. Common side effects are rare but include hypersensitivity reactions.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    47 views3 pages

    Azathioprine - Frequent:: Anti-Inflammatory Immunosuppressive That Can Decrease Joint Damage and Disability

    Uploaded by

    Jordz Placi
    This document summarizes key information about the mechanism of action, indications, contraindications, common side effects, and nursing considerations for azathioprine, acetaminophen, and corticosteroids. Azathioprine works by antagonizing purine metabolism and inhibiting DNA, protein, and RNA synthesis to produce its anti-inflammatory and immunosuppressive effects. Common side effects include nausea, vomiting, and anorexia. Nursing considerations include assessing for allergies and monitoring for gastrointestinal disturbances. Acetaminophen provides relief of mild to moderate pain by inhibiting prostaglandin synthesis in the central nervous system and blocking pain impulses peripherally. Common side effects are rare but include hypersensitivity reactions.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
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    MECHANISM OF INDICATION CONTRAINDICATION COMMON SIDE NURSING

    ACTION EFFECTS CONSIDERATION


    Azathioprine Antagonizes anti-inflammatory -Hypersensitivity to -Frequent: -History:
    purine immunosuppressive azaTHIOprine Nausea, vomiting, Allergy to
    Classification: metabolism, that can decrease - pregnancy anorexia azathioprine:
    Immunosuppressan inhibits DNA, joint damage and -lactation (particularly Rheumatoid
    t. protein, and RNA disability  Alcoholism during early arthritis patients
    synthesis. -chronic liver disease treatment and previously treated
    with large doses). with alkylating
    Dosage and route: agents
    50 mg -Occasional: Rash.
    OD - Give with food or
    -Rare: Severe in divided doses to
    nausea/vomiting reduce potential
    with diarrhea, for GI disturbances.
    abdominal pain,
    hypersensitivity
    reaction.
    Acetaminophen Appears to inhibit relief of mild to -Hypersensitivity to -Hypersensitivity -Baseline
    prostaglandin moderate pain acetaminophen reaction. assessment:
    Classification: synthesis in the -severe hepatic If given for
    Analgesics CNS and, to a impairment or severe Anorexia analgesia, assess
    lesser extent, active liver disease Nausea onset, type,
    Dosage and route: block pain diaphoresis location, duration
    impulses through of pain. Effect of
    325 mg peripheral action. medication is
    PRN Acts centrally on reduced if full pain
    hypothalamic response recurs
    heat-regulating prior to next dose
    center, producing
    peripheral -Intervention
    vasodilation /evaluation:
    Assess for clinical
    improvement and
    relief of pain, fever
    Corticosteroids Suppress  help to slow and Absolute Headache, Monitor vital sign
    migration of stop the processes contraindication: insomnia, weight
    Classification: polymorphonuclea in your body that gain, nausea, Taper doses when
    Glucocorticoids r leukocytes (PML) make the molecules -Infectious arthritis vomiting. discontinuing high-
    and reverse involved in your -Bacteremia increased blood dose or long-
    Dosage and route: increased capillary inflammatory -Periarticular glucose termtherapy.
    permeability by response. -cellulitis
    their anti- /ulceration Changes in · Do not give live
    100 mg inflammatory Osteomyelitis appearance virusvaccines
    TID effect. Suppress withimmunosuppre
    immune system by Relative ssivedoses
    decreasing activity contraindication; of corticosteroids.
    of lymphatic -Do not stop taking
    system. -Uncontrolled the oral drug
    diabetes without consulting
    -Uncontrolled the health care
     hypertension provider
    -Joint instability -avoid exposure to
    -Severe mechanical infections, abilty to
    deterioration of joint fight infections is
    reduced.
    -instruct the
    patient that they
    nay experience
    these side effects

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