DRUG ORDER MECHANISM OF RATIONALE SIDE EFFECTS NURSING CONSIDERATIONS

(Generic name, ACTION

Dosage, Route,
Frequency)
Generic Name: Inhibit HMG-CoA Used for the *No side effects manifested  Patient followed a standard
Atorvastatin reductase, an treatment of on the patient* cholesterol-lowering diet before and
early (and rate- elevated during therapy.
Brand name: limiting) step in total cholest  constipation/diarrhea  Before treatment, assess patient for
Lipitor cholesterol erol, LDL, trig  nausea underlying causes for
biosynthesis. lycerides,  heartburn hypercholesterolemia and obtain a
Classification: and to  headache baseline lipid profile.
Dyslipidaemic elevate HDL  mild muscle pain  Advised on proper diet on how to
Agent cholesterol. control and prevent
hypercholesterolemia
Stock:
80 mg

Dosage:
80 mg Tab ODHS
 DRUG ORDER MECHANISM OF RATIONALE SIDE EFFECTS NURSING CONSIDERATIONS
(Generic name, ACTION
Dosage, Route,
Frequency)
•Citicoline Citicoline is a To treatment *No side effects manifested on  Monitored blood pressure, pulse
derivative of cerebrovascu the patient* and heart rate.
Brand Name: choline and lar disorders  Assessed allergic reaction like GI
Zynapse cytidine involved in  GI disorders (ie stomach disturbances.
the biosynthesis of pain, diarrhea)  Instructed relative to give only
Classification: lecithin. It is  vascular effects (ie: prescribed dose.
Neurologic claimed to increase hypotension, tachycardia,  Advised relative to consult the
blood flow and bradycardia) physician if any problems occur to
Stock: oxygen the patient during medication.
1gm consumption in the
brain.
Dosage:
1gm TIV
 DRUG ORDER MECHANISM OF ACTION RATIONALE SIDE EFFECTS NURSING CONSIDERATIONS
(Generic name,
Dosage, Route,
Frequency)
• Pioglitazone Pioglitazone acts as a selective Promotes uptake of *No side effects Hepatic Impairment
agonist at Peroxisome glucose by cells. manifested on the Mild impairment with ALT 2.5 times
Brand name: Proliferator Activated Receptor patient* the upper limit of normal (ULN) or
Actos Gamma (PPARγ) in target tissues Promotes use of less: Use caution with dosage and
for insulin action such as glucose for energy. The most common titration. May start and continue
Classification: adipose tissue, skeletal muscle, side effects of Actos pioglitazone cautiously; periodically
Antidiabetics and liver. Activation of PPAR- alone or in check liver function tests (LFTs) and
gamma receptors increases the combination with serum bilirubin.
Stock: transcription of insulin- sulfonylureas,
15 mg responsive genes involved in the metformin, or insulin
control of glucose production, are:
Dosage: transport, and utilization. In this  Upper respiratory
30mg Tab OD way, pioglitazone both tract infection
enhances tissue sensitivity to  Headache
insulin and reduces the  Sinusitis
production of glucose via the  Muscle aches
liver (hepatic gluconeogenesis).  Tooth disorders
Thus, insulin resistance  Hypoglycemia (low
associated with type 2 diabetes blood sugar)
mellitus is improved without an  Sore throat
increase in insulin secretion by
pancreatic β cells.
 DRUG ORDER MECHANISM OF RATIONALE SIDE EFFECTS NURSING CONSIDERATIONS
(Generic name, ACTION
Dosage, Route,
Frequency)
•Gliclazide  Lowers blood To lower *No side effects  Observed for signs and symptoms of
glucose by blood manifested on the hypoglycemia (hunger, weakness,
Brand name: stimulating the glucose in patient* sweating, dizziness, tachycardia, anxiety).
Diamicron MR release of insulin diabetic
 Assessed patient for allergy to
from the patients. Endo: hypoglycemia
sulfonylureas.
Classification: pancreas and
Antidiabetics increasing GI: abdominal pain,
 Monitored renal function periodically in
sensitivity to diarrhea, dyspepsia, ↑
patients with mild to moderate renal
Stock: insulin at liver enzymes, nausea,
dysfunction. May cause ↑ creatinine and
60 mg receptor sites. vomiting
hyponatremia.
Dose: Derm: photosensitivity,
60 mg tab OD rash
 DRUG ORDER MECHANISM OF RATIONALE SIDE EFFECTS NURSING CONSIDERATIONS
(Generic name, ACTION
Dosage, Route,
Frequency)
• Vitamin B Act as coenzyme Vitamin B *No side effects manifested  Advised patient to take vitamin B
complex and are essential complex on the patient* complex by mouth with a glassful of
for the deficiency water (250 ml)
Brand name: metabolism of (prophylaxis Possible side effects.  Recommended diet which contains the
Polynerv proteins, and needed vitamins
carbohydrates treatment) High doses of supplemental
Classification: and fatty acids. B3 (niacin) may lead to:
Vitamins and vomiting,
Minerals  high blood sugar
levels,
Stock:  skin flushing and even
500mg  liver damage.
High doses of B6 can cause:
Dosage:  nerve damage,
500mg/tab, 1Tab  light sensitivity and
OD  painful skin lesions.