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(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT)

(19) World Intellectual Property


Organization I
International Bureau
(10) International Publication Number
(43) International Publication Date WO 2013/134856 Al
19 September 2013 (19.09.2013) P O PCT

(51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every
m m 13/52 (2006.01) m m 13/514 (2006.01) kind of national protection available): AE, AG, AL, AM,
A41D 13/00 (2006.01) H01R 13/703 (2006.01) AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY,
HOIR 11/16 (2006.01) HO2G 15/013 (2006.01) BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM,
DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT,
(21) International Application Number:
HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP,
PCT/CA20 13/000221 KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD,
(22) International Filing Date: ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI,
12 March 2013 (12.03.2013) NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU,
RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ,
(25) Filing Language: English TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA,
(26) Publication Language: English ZM, ZW.

(30) Priority Data: (84) Designated States (unless otherwise indicated, for every
61/61 1,944 16 March 2012 (16.03.2012) US kind of regional protection available): ARIPO (BW, GH,
GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ,
(71) Applicant: CARRE TECHNOLOGIES INC. [CA/CA]; UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ,
5795, avenue de Gaspe, 3e etage, bureau 218, Montreal, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK,
Quebec H2S 2X3 (CA). EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV,
MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM,
(72) Inventors: FOURNIER, Pierre-Alexandre; 24, avenue
TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW,
Shamrock, suite 2 1 1, Montreal, Quebec H2S 1A4 (CA).
ML, MR, NE, SN, TD, TG).
ROY, Jean-Fran? ois; 324, rue Villeray, Sherbrooke,
Quebec H2R 1 G7 (CA). ROBILLARD, Charles; 1215, Published:
rue Dutchy, Saint-Lazare, Quebec J7T 1Z9 (CA).
— with international search report (Art. 21(3))
GAGNON, Stephan; 360, rue Champlain, Rosemere,
Quebec J7A 3X8 (CA).
(74) Agents: BEAUCHESNE, Sandra et al; BCF LLP, 1100
Rene-Levesque Blvd. West, 25th Floor, Montreal, Quebec
H3B 5C9 (CA).

(54) Title: WASHABLE INTELLIGENT GARMENT AND COMPONENTS THEREOF

Figure 14

Front Back

(57) Abstract: The present relates to a washable interconnection patch, a connection assembly, and an intelligent washable garment
equipped therewith. The patch receives and interconnects wires to a cable. The patch comprises two matching pieces interlocking to -
gether so as to define there between two opposite apertures. One of the apertures is adapted to receive and hold the wires, and the
o other aperture is adapted to receive and hold the cable. One of the two matching pieces defines on an interior face a channel to inter
connect the wires to the cables. The connection assembly comprises a male connector and a female connector. The male connector
o defines a series of independent connection points along a length thereof. The female connector is adapted to receive the male con -
nector, and defines along a length of an inner surface thereof a series of contact points. When the male connector is inserted within
the female connector, the connection points and the contact points are aligned and in contact together.
WASHABLE INTELLIGENT GARMENT AND COMPONENTS THEREOF

[0001] The present relates to a washable interconnection patch, a male-


female connector assembly, and a washable intelligent garment equipped with
such a washable interconnection patch and male-female connector assembly.

BACKGROUND

[0002] Physiological sensors have long been known and widely used for
medical and health related applications. Various physiological sensors embedded
in textile or garments, sometimes called portable or wearable sensors, have been
described before in publications and patents (Portable Blood Pressure, Patent
number: 4889132, Filing date: Sep 26, 1986 Issue date: Dec 26, 1989; Portable
device for sensing cardiac function, Patent number: 4928690, Filing date: Apr 25,
1988, Issue date: May 29, 1990). The term "wearable sensors" is now commonly
used to describe a variety of body-worn sensors to monitor activity, environmental
data, body signals, biometrics, health related signals, and other types of data.

[0003] Electrocardiogram (ECG) electrodes made of conductive textile,


conductive polymer, metal and other materials used in wearable sensors have
been described in patents such as (Textile-based electrode, Patent number:
7970451 , Filing date: Dec 3 1 , 2008, Issue date: Jun 28, 201 1) .

[0004] Textile-based Respiratory Inductive Plethysmography sensors have


been described in patents such as (Method and apparatus for monitoring
respiration, Patent number: 4308872 Issue date: Jan 5 , 1982).

[0005] Multi-parameter wearable connected personal monitoring systems


(Zephyr Technology' BioHarness, Qinetiq's Traintrak, Weartech's GOW, Nuubo's
nECG) are already available on the market.
[0006] However, the single or multi-parameter systems known in the
industry use clip buttons made of conductive material for connecting the textile
sensors to an electronic module. These clip buttons limit the number and types of
interconnections available between the electronic module and the textile sensors.

[0007] Connectivity is a domain with many technological challenges to the


manufacturer of e-textile solutions, intelligent garments, wearable sensors, and
multi-parameter wearable connected personal monitoring systems. There is thus a
need for improved connectivity solutions, and for garments equipped with such
connectivity solutions.

BRIEF DESCRIPTION OF THE DRAWINGS

[0008] In the appended drawings:

[0009] Figure 1 is a schematic representation of an interconnection patch


that can be assembled in a garment, with a textile-covered cable and a washable
male connector.

[001 0] Figure 2a is a top view of a washable interconnection patch adapted


for electrical and optical interconnections.

[001 1] Figure 2b is a top view of the washable interconnection patch


showing wire interconnections inside the patch before encapsulation.

[001 2] Figure 3 is a cross-sectional side view of a male and female


washable connector, showing spring-loaded electrical pins in contact with a printed
circuit board of the male connector.

[001 3] Figure 4 is a cross-sectional view of the male and female connector,


showing a curve (called "ski" or "banana") in the printed circuit board of the male
connector, allowing the spring-loaded electrical pins to be put in compression
without applying a side force on the pin of the female connector while inserting.

[0014] Figure 5 is a cross-sectional view of the female connector, without


the spring-loaded electrical pins.

[0015] Figure 6 is a view of the male connector assembled with a cable


segment, inserted in the female connector.

[0016] Figure 7 is a side view of the male connector with the spring-loaded
pins in contact with the printed circuit board conductive pads.

[00 7] Figure 8 is a side view of the printed circuit board (PCB) of the male
connector showing the curve that pushes the spring-loaded pins during insertion.

[0018] Figure 8a is a bottom view of the PCB of the male connector showing
circular electrical contacts.

[0019] Figure 8b is a top view of the PCB of the male connector showing
rectangular contacts for soldering and printed wires.

[0020] Figure 9 is a cross-sectional view of the female connector made with


standard spring-loaded contacts embedded in a plastic component and aligned with
an aperture shaped like a cylinder to host the male connector.

[0021] Figure 10 is a bottom view of the plastic component of the female


connector showing the shape and apertures ready to host a row of spring-loaded
contacts.

[0022] Figure 11 is a view of the male connector and a cable segment


inserted in the side of the female connector of a small electronic device.

[0023] Figure 12 is Hexoskin garment with a male connector. The garment


illustrated has conductive textile electrodes and textile-based respiratory inductive
plethysmography sensors connected to the interconnection patch with flexible and
elastic wires.

[0024] Figure 13 shows garments that use the present patch and connection
system to connect textiles sensors for heart and breathing monitoring to an
electronic device with an accelerometer and a Bluetooth wireless connection. The
electronic device also contains analog and digital filters and amplifiers, a
microprocessor device, solid-state memory storage, sensor circuits, power
management circuits, buttons, and other circuits.

[0025] Figure 14 shows a garment with electrical and optical sensors that
use the present system to connect textiles, electrical, thermal, and optical sensors
for cardiac monitoring, breathing monitoring, blood pressure monitoring, skin
temperature and core temperature monitoring to an electronic device with position
sensors and a wireless data connection.

[0026] Figure 15 shows a device that includes a female connector,


connected to a cable with a right-angle male connector. The device has a button
that can be used to record an event, initiate wireless pairing using a protocol like
Bluetooth, or reset the device. In this example, the device has 3 light emitting
diodes used to communicate with users.

[0027] Figure 16 shows a diagram of sensor front-end electronic module


that can have the electronic device to process the analog physiological data,
digitize the analog value using an analog to digital converter, and processing the
physiological data using a CPU.
[0028] Figure 17 shows a diagram of how the device can be used to record
the physiological signals from the body sensors and transmit it first to any
connected computing device that can be used to interpret the signals or an Internet
gateway, and then to a distant computing and storage system.

[0029] Figure 18 shows a diagram of functional components used in the


electronic device.

[0030] Figure 19 shows a diagram of a physiological data processing flow, in


this case the data coming from the electrocardiogram sensor.

DETAILED DESCRIPTION

[0031] The foregoing and other features of the present garment and
components thereof will become more apparent upon reading of the following non-
restrictive description of examples of implementation thereof, given by way of
illustration only with reference to the accompanying drawings.

[0032] Connectivity is a domain with many technological challenges for


designers and manufacturers of e-textile solutions, intelligent garments, wearable
sensors, and multi-parameter wearable connected personal monitoring systems.

[0033] In an aspect, the present specification describes a washable


electronic male-female connector. The male connector is designed to be attached
to a washable and/or wearable sensor system (as exemplary shown in Figure 1)
and comprises a cable, which may be covered with textile, and an interconnection
patch where many electric and/or optical wires can be connected to the cable as
exemplary shown in Figure 2a and 2b. The male connector may further comprise
strain relief components.

[0034] The male connector and its components can be made of various
materials. In one example, the patch and strain relief components may be made of
any of the following material: silicone, rubber, or another flexible material over-
molded over the cable. The cable may be made of many color-coded electrical
wires, bundled together using a textile fabric knitted around the wires. The male
connector and strain relief components may be made using over-molded resin. In
one example electrical interconnections between wires coming from the garment
and the wires in the cable are made using a small open crimp or a crimp tube (as
exemplary shown in Figure 2b, and the interconnection is sealed using silicone,
rubber, or any other sealing material compatible with the over-molded patch.

[0035] The interconnection patch can be made using a manufacturing


process that does not require heating, for example crimps and/or glue and/or
silicone with low curing temperature, which has among its advantages the benefit of
reducing the risk to deteriorate or destroy heat sensitive textiles that can be used in
a garment.

[0036] In a particular embodiment, the male connector is designed with a

small curve at one of its longitudinal extremity to be adapted to lower spring-loaded


contacts during insertion in the female connector (see Figures 4 and 8). In one
example, the male connector is made of a printed circuit board shaped like a ski
(see Figure 8), electronic contacts with the female connector being made when
engaged with conductors printed at the bottom of the ski-shaped circuit board
(Figure 8a), while the wires are soldered on the top of the circuit board (Figure 8b)
before it is over-molded to become the male connector and the strain relief for the
wires and cable connected to the washable interconnection patch. The strain relief
(Figure 11) can also be made at a right angle (Figure 15) to make the cable follow
the side of the device and reduce the space needed for the cable and device in a
pocket on the garment. For example, the circuit board and cable may be
overmolded in one piece to create the male connector. The strain relief is then the
part of the connector attaching the cable to the plastic shell of the male connector
to avoid putting tension on the soldered connection between the wires and the
circuit board.
[0037] In a further embodiment, the electrical contacts on the male
connector are plated with gold or another conductive material not affected by
oxydation or degradation caused by air, light, water, soap, enzymes or other
chemical or biological products.

[0038] The female connector may comprise spring-loaded contacts that are
lined up along an aperture shaped like a cylinder (see Figures 4 and 9). The
aperture is asymmetric to facilitate the alignment of the contacts with the contacts
of the male connector (see Figure 3). The female connector can be made as one
piece including the spring-loaded contacts, or two pieces including for example one
row of spring-loaded connectors and an injection molded plastic piece defining an
asymmetric aperture (see Figure 10).

[0039] Electric and/or optic connection between the male and female
connectors is completed upon complete engagement of the male connector within
the female connector, which permits the contacts of the male connector to be
aligned with the spring-loaded contacts of the female connector (see Figure 7).

[0040] The device starts recording the physiological signals automatically


from the sensors upon complete connection of the male connector within the
female connector, and stops recording when the male connector is removed from
the female connector. This feature simplifies the use of the recording device and
reduces power consumption from the battery when the device is not connected.

[0041] An example of use of the present male-female connector and the


present interconnection patch are wearable physiological monitoring garments as
shown in Figures 12 and 3 .

[0042] Reference is now made to Figure 14, which depicts another


exemplary use of the present system, where an upper-body garment is equipped
with physiological sensors to measure body activity and state with a recording,
processing and transmitting wearable device that connects to physiological
sensors. The garment is embedded with electrodes for electrocardiogram (ECG) or
electromyogram (EMG) recordings, thermal sensors for skin temperature
monitoring, multidimensional acceleration and position sensors for position and
movement monitoring, microphone for heart and lung auscultation, inductance
plethysmography sensors to measure changes in volume of the upper body, optical
sensors for body spectrophotometry, and a blood pressure sensor on the left arm of
the garment. This wearable physiological sensor system provides enhanced users'
mobility compared to previous systems, allows simultaneous recording of all the
aforementioned signals, allows simultaneous encoding and wireless transmission
of all the aforementioned signals, allows automatic processing, analysis, and
modeling of all the aforementioned signals, is less vulnerable to position and
motion artifacts hence capable of producing high quality signals during sleep,
running, exercising and other normal activities. The sensor system, including the
present male-female connector, and the interconnection patch, is thus washable in
a regular domestic washing machine. Any electronic device may be connected to
the garment using the present male-female connector. The electronic device may
thus be located in a pocket designed for carrying. The electronic device can
communicate with mobile phones and computer devices using a wireless or wired
communication protocol. When used with low height profile embedded sensors, the
present system makes it possible to wear the garment during sleep, physical
activity, and in other contexts.

[0043] In one example, the electronic device is further equipped with a button

that can be used to record an event, initiate wireless pairing using a protocol like
Bluetooth, or reset the device. In this example shown in Figure 5 , the device has 3
light emitting diodes used to communicate with users, for example to confirm to a
wearer of the garment that the garment is connected, the electronic device is
connected using a wireless link, a state of a battery of the electronic device, any
malfunction or any other information the electronic device must communicate to the
user. The electronic device may contain several analog and digital circuits to record
and process the physiological signals as shown on Figure 16. The electronic device
can further implement all the normal functions of a computing device as shown on
Figure 18. The device can be connected to other computing and networking
devices using a wired or wireless protocol as shown on Figure 17, and can use
another computing or networking device to communicate with a remote server, a
distance storage system, or a distance computing system, which can provide
automatic physiological data analysis services and help with the interpretation of
physiological signals. For example, such an automatic physiological data analysis
can be constructed using a stack of simple processing units to achieve a high-level
understanding of the original physiological signal, such as detailed cardiac activity
shown on Figure 19, symptoms, and pathologies.

[0044] Although the present interconnection patch, male-female connector


and washable intelligent garment have been described in the foregoing description
by way of illustrative embodiments thereof, these embodiments can be modified at
will, within the scope of the appended claims without departing from the spirit and
nature of the appended claims.
What is claimed is:

1. A washable interconnection patch for receiving and interconnecting wires to


a cable, the patch comprising:
two matching pieces interlocking together so as to define therebetween two
opposite apertures, one of the apertures being adapted to receive and hold the
wires and the other aperture being adapted to receive and hold the cable, one of
the two matching pieces defining on an interior face a channel to interconnect the
wires to the cables.

2. The patch of claim 1, wherein one of the two matching pieces further
comprises a fastening member for fastening the interlocked matching pieces to a
fabric.

3. The patch of claim 1, wherein the two matching pieces are further adapted
to be filled with a sealant.

4. A connection assembly comprising:


a male connector, the male connector defining a series of independent
connection points along a length thereof; and
a female connector adapted to receive the male connector, the female
connector defining along a length of an inner surface thereof a series of contact
points,
whereby when the male connector is inserted within the female connector, the
connection points and the contact points are aligned and in contact together.

5. The assembly of claim 4 , wherein:


the male connector's cross section is shaped like a C and the connection points
are located in a concave section thereof; and
an entry of the female connector is C-shaped.

6 . The assembly of claim 4 wherein:


The male connector comprises electrical contacts plated with gold or another
conductive material.

7. The assembly of claim 5 , wherein the series of independent connection


points of the male connector are part of a printed circuit board.

8. The assembly of claim 6 , wherein the male connector further comprises a


resilient means to press the connection points of the male connector against the
contact points of the female connector when the male connector is inserted into the
female connector.

9 . The assembly of claim 4 , wherein the connection points and contact points are

electrical points.

10. The assembly of claim 4 , wherein the male connector is adapted for use in a
washable garment.

11. An intelligent washable garment, the garment comprising:


a plurality of sensors, each of the sensors having a corresponding cable;
an electronic device for receiving signals generated by the plurality of
sensors, the electronic device comprising:
a casing;
a connection assembly comprising a male connector and a female
connector, the male connector defining a series of independent connection
points along a length thereof, each of the connection points being electrically
connected to one of the cables of the sensors, the female connector being
adapted to receive the male connector, the female connector defining along
a length of an inner surface thereof a series of contact points, wherein when
the male connector is inserted within the female connector, the connection
points and the contact points are aligned and in contact together and the
signals received by the male connector from the sensors are transferred to
the female connector; and
a processing unit in electrical communication with the female
connector for processing the signals received by the female connector.

12. The processing unit of claiml 1 capable of recording physiological signals


automatically.

13. The processing unite of claim 12 wherein the device starts recording the
physiological signals automatically from the sensors upon complete connection of
the male connector within the female connector, and stops recording when the
male connector is removed from the female connector.
INTERNATIONAL SEARCH REPORT International application No.
PCT/CA20 13/000221

A. CLASSIFICATION OF SUBJECT MATTER


IPC: HOIR 13/52 (2006.01) . A4W 13/00 (2006.01) . HOIR 11/16 (2006.01) . H01R 13/514 (2006.01) .
H01R 13/703 (2006.01) . H02G 15/013 (2006.01)
According to International Patent Classification (IPC) or to both national classification and IPC

B . FIELDS SEARCHED
Minimum documentation seaixhed (classification system followed by classification symbols)
H01R 13/52 (2006.01) . A41D 13/00 (2006.01) . H01R 11/16 (2006.01) . H01R 13/514 (2006.01) .
H01R 13/703 (2006.01) . H02G 15/013 (2006.01)

Documentation searched other than minimum documentation to the extent that such documents are included n the fields searched

Electronic database(s) consulted during the international search (name of database(s) and, where practicable, search terms used)
Databases: Epoque (English full text database), Canadian Patents Database
Search terms: connector, sensor, seal, male, female, inline, c-shaped, garment, washable

C . DOCUMENTS CONSIDERED TO BE RELEVANT


Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.

X US6305962 (Maher, T. et al.) 23 October 2001 (23-10-2001 ) 4-9


*Figs. 9A-9C, col. 11, lines 25-53*
Y 10-13

Y US20080 15454 (Gal, Y.) 17 January 2008 (17-01-2008) 10-13


*Fig. 1A*

A US6645008 (Massey, P . et al. ) 11 July 2002 ( 11-07-2002) 1-3


*Figs. 3-10*

A US2005054941 Ting, J . et al.) 10 March 2005 ( 10-03-2005) 4-13


*Figs. 6 and 18*

A WO2012160123 (Broedsgaard, D.) 29 November 2012 (29-1 1-2012) 4-13


*Figs. 16-18*

A US2008064964 (Nagata, S . et al.) 13 March 2008 ( 13-03-2008) 4-13


*Fiss. 5A and 5B*

Further documents are listed in the continuation of Box C . [X ] See patent family annex.
Special categories of cited documents : Ύ" later document published after the international filing date or priority
date and not m conflict with the application but citecTto understand
document defining the general state of the art which is not considered the principle or theorv underlying the invention
to be of particular relevance
X" document of particular relevance the claimed invention cannot be
earlier application or patent but published on or after the international considered novel or cannot be considered to involve an inventive
filing date step when the document is taken alone
document which may t r n doubts on priority clami(s) or which is "Y document of particular relevance the claimed invention cannot be
cited to establish the publication date of another citation or other considered to involve an inventive step when the document is
special reason (as specified) combined rath one or more other such documents such combination
being obvious to a person skilled m the art
document referring to an oral disclosure, use, exhibition or other means
document member of the same patent family
document published prior to the international filing date but later than
the priority date claimed

Date of the actual completion of the international search Date of mailing of the international search report

29 May 2013 (29-05-2013) 3 1 May 2013 (3 1-05-2013)


Name and mailing address of the ISA CA Authorized officer
Canadian Intellectual Property Office
Place du Portage I, C I 14 - 1st Floor, Box PCT Jim Triantafillou (819) 934-4268
50 Victoria Street
Gatineau, Quebec K1A 0C9
Facsimile No.: 001-819-953-2476

Form PCT/ISA/210 (second sheet ) (July 2009) Page 3 of 4


INTERNATIONAL SEARCH REPORT International application No.
PCT/CA20 13/000221

Box No. II Observations where certain claims were found unsearchable (Continuation of item 2 of the first sheet)
This international search report has not been established in respect of certain claims under Article 17(2)(a) for the following
reasons :

1. [ ] Claim Nos. :
because they relate to subject matter not required to be searched by this Authority, namely :

2. [ ] Claim Nos. :
because they relate to parts of the international application that do not comply with the prescribed requirements to such an extent
that no meaningful international search can be carried out, specifically :

3. [ ] Claim Nos. :
because they are dependent claims and are not drafted in accordance with the second and third sentences of Rule 6 .4( a).

Box No. Ill Observations where unity of invention is lacking (Continuation of item 3 of first sheet)

This International Searching Authority found multiple inventions in this international application, as follow s :

Group A (Claims 1-3): A washable interconnection patch for interconnecting wires to a cable.

Group B (Claims 4-13): A washable garment including a connection assembly with male and female connectors.

1. [ ] As all required additional search fees were timely paid by the applicant, this international search report covers all
searchable claims.

2. [X] As all searchable claims could be searched without effort justifying additional fees, this Authority did not invite
payment of additional fees.

3. [ ] As only some of the required additional search fees were timely paid by the applicant, this international search report
covers only those claims for which fees were paid, specifically claim Nos. :

4. [ ] No required additional search fees were timely paid by the applicant. Consequently, this international search report is

restricted to the invention first mentioned in the claims; it is covered bv claim Nos. :

Remark on Protest [ ] The additional search fees were accompanied by the applicant's protest and, where applicable,
the payment of a protest fee.
[ ] The additional search fees were accompanied by the applicant's protest but the applicable protest
fee was not paid within the time limit specified in the invitation.
[ ] No protest accompanied the payment of additional search fees.
Form PCT/ISA/210 (continuation of first sheet (2)) (July 2009) Page 2 of 4
INTERNATIONAL SEARCH REPORT International application No.
Information o patent family members PCT/CA20 13/000221

Patent Document Publication Patent Family Publication


Cited in Search Report Date Member(s) Date

US6305962B1 23 October 2001 (23-10-2001 ) AU3490200A 04 September 2000 (04-09-2000)


WO0049684A1 24 August 2000 (24-0S-2000)
WO0049684A9 27 September 2001 (27-09-2001 )

US2008015454A1 17 January 2008 (17-01-2008) AU2005286769A1 30 March 2006 (30-03-2006)


AU2006342788A1 08 November 2007 (08-1 1-2007)
CA2580246A1 30 March 2006 (30-03-2006)
CA2625267A1 08 November 2007 (08-1 1-2007)
EP1791467A2 06 June 2007 (06-06-2007)
EP1791467A4 2 1 April 2010 (21-04-2010)
EP1791467B1 27 March 2013 (27-03-2013)
EP1940287A2 09 July 2008 (09-07-2008)
EP1940287A4 14 April 2010 (14-04-2010)
EP1940287B1 19 September 2012 (19-09-2012)
JP2008513152A 0 1 May 2008 (01-05-2008)
JP2009518057A 07 May 2009 (07-05-2009)
US2006122528A1 08 June 2006 (08-06-2006)
US8034001 B2 11 October 201 1 ( 1 1-10-201 1)
US2012071793A1 22 March 2012 (22-03-2012)
WO2006034291A2 30 March 2006 (30-03-2006)
WO2006034291A3 12 October 2006 (12-10-2006)
WO2007126435A2 08 November 2007 (08-1 1-2007)
WO2007126435A3 20 March 2008 (20-03-2008)

US6645008B2 11 November 2003 ( 1 1-1 1-2003) EP1352452A1 15 October 2003 (15-10-2003)


GB0100774D0 2 1 February 2001 (21-02-2001)
JP2004518323A 17 June 2004 (17-06-2004)
JP3993104B2 17 October 2007 (17-10-2007)
US2002089399A1 11 July 2002 ( 1 1-07-2002)
WO02056425A1 18 July 2002 (18-07-2002)

US2005054941A1 10 March 2005 (10-03-2005) AU2004277381A1 14 April 2005 (14-04-2005)


AU2004277381 B2 24 April 2008 (24-04-2008)
AU2008203307A1 14 August 2008 (14-08-2008)
AU2008203307B2 20 May 2010 (20-05-2010)
AU2010212423A1 09 September 2010 (09-09-2010)
AU2010212423B2 20 September 2012 (20-09-2012)
CA2689267A1 18 December 2008 (18-12-2008)
EP1659940A2 3 1 May 2006 (31-05-2006)
EP1659940A4 07 March 2012 (07-03-2012)
EP2150171A1 10 February 2010 (10-02-2010)
US7559902B2 14 July 2009 (14-07-2009)
US2007299325A1 27 December 2007 (27-12-2007)
US2010041974A1 18 February 2010 (18-02-2010)
WO2005032447A2 14 April 2005 (14-04-2005)
WO2005032447A3 09 March 2006 (09-03-2006)
WO2008153786A1 1 December 2008 (18-12-2008)

WO2012160123A1 29 November 2012 (29-1 1-2012) None

US2008064964A1 13 March 2008 (13-03-2008) CN1933777A 2 1 March 2007 (21-03-2007)


CN1933777B 22 September 2010 (22-09-2010)
EP1731094A1 13 December 2006 (13-12-2006)
EP1731094A4 29 July 2009 (29-07-2009)
EP2324764A2 25 May 201 1 (25-05-201 1)
EP2324764A3 18 January 2012 (18-01-2012)
JP4698582B2 08 June 201 1 (08-06-201 1)
JP201 1098214A 19 May 201 1 (19-05-201 1)
WO2005089645A1 29 September 2005 (29-09-2005)

Form PCT/ISA/210 (patent family annex ) (July 2009) Page 4 of 4

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