Mitosisnotes 170209212950 2

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Mitosis Notes

Mitosis
 Remember that mitosis is
the name of the cell division
that eukaryotic cells go
through to create a new cell.
 Mitosis is all about the
division of the nucleus and
there are names for each
step that you will need to
learn.
Cell Division

 Mitosis- process of
making new
somatic (nonsex)
cells like skin cells
(clones)
Cell Cycle
 The Cell Cycle –
a repeating set of
events that make
up the life of a
cell.
 Mitosis is actually
a name of one of
the cell cycle
steps usually
referred to as the
M phase.
Cell Cycle
 But most people call
the whole process
Mitosis instead of
the cell cycle,
because it is a very
important step.
Cell Division
 Where do new cells
come from?
 All cells came from
preexisting cells.
Steps of the Cell Cycle

 1. Interphase – the longest phase,


80% of cells life is in this phase.
 Steps of Interphase:
 G1 phase – growth of cell
 G0 phase – inactive stage.
 S phase – DNA is replicated (“S”
synthesis of DNA)
 G2 phase – growth of cell; prepares
for cell division
Steps of the Cell Cycle
 G0 phase – non dividing
state after the G1 phase;
 This is the only time a cell can
be stopped from dividing, and
is why a cell spends the
majority of its life in
interphase.
 Some cells in the human body
like spinal cord cells get stuck
in the G0 phase and never
divides again, which is why
spinal cord injuries don’t heal.
Cell Cycle
 2. Mitosis – division of the nucleus; a continuous
process divided into 4 phases
 A. Prophase
 B. Metaphase
 C. Anaphase
 D. Telophase
G1 phase

M phase

S phase

G2 phase
Mitosis
 The following is what
happens during each phase
of mitosis.

 A. Prophase
 Chromosomes appear
 The nucleus begins to break
down
 Centrioles appear and
produce spindle fibers
Mitosis
 B. Metaphase
 Chromosomes align
along the equator of the
cell
 Spindles Fibers move
chromosomes to the
equator.
 Spindle Fibers are
attached to the centrioles
(at poles) and connect to
the centromeres on
chromosomes.
Mitosis
 C. Anaphase
 Chromosomes are pulled
to the pole by the
contraction of the spindle
fibers
 So, the sister chromatids
are separated at the
centromere
Mitosis
 D. Telophase
 The chromosomes begin to form a new nucleus.
 A new cell membrane/wall begins to form so the two cells can
separate
 If there is a cell wall what type of cell are we looking at?
Cell Cycle
 3. Cytokinesis – division of the cytoplasm
 The chromosomes start to uncoil and become less dense
 You now have two new genetically identical cells.
 Cytokinesis actually happens during Telophase, so you would
actually say Telophase/Cytokinesis.
Telophase/Cytokenisis

 See cleavage in
animal cells

 See Cell plate form


in plant cells.

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