The Effect of Ankle-Foot Orthoses On Community-Based Walking in Cerebral Palsy: A Clinical Pilot Study
The Effect of Ankle-Foot Orthoses On Community-Based Walking in Cerebral Palsy: A Clinical Pilot Study
The Effect of Ankle-Foot Orthoses On Community-Based Walking in Cerebral Palsy: A Clinical Pilot Study
Purpose: To examine the effect of ankle-foot orthoses (AFO) on walking activity in children with cerebral
palsy (CP). Methods: We used a randomized cross-over design with 11 children with bilateral CP, mean age
4.3 years. Subjects were randomized to current AFO-ON or AFO-OFF for 2 weeks and then crossed over.
Walking activity (average total steps/day), intensity, and stride rate curves were collected via an ankle ac-
celerometer. Group effects were examined with the Wilcoxon signed-rank test and within-subject effects
examined for more than 1 standard deviation change. Results: No significant group difference was found
in average total daily step count between treatment conditions (P = .48). For the AFO-ON condition, 2 sub-
jects (18%) increased total steps/day; 4 (36%) increased walking time; 2 (18%) had more strides at a rate
of more than 30 strides/min; and 2 (18%) reached higher peak intensity. Conclusions: Clinically prescribed
AFO/footwear did not consistently enhance walking activity levels or intensity. Larger studies are warranted.
(Pediatr Phys Ther 2016;28:179–186) Key words: ambulation, ankle-foot orthoses, cerebral palsy, child, gait
Abbreviations: AFO, ankle-foot orthosis; DF, dorsiflexion; GMFCS, Gross Motor Function Classification System; PF, plantar flexion; SVA, shank-to-
vertical angle.
a Positive number in degrees from vertical = inclined shank, negative number in degrees from vertical = reclined shank.
b SVA optimized.15
percent time walking) and intensity (number of strides/day and moderate rates (30-60 strides/min), whereas the day-
>30 strides/min, peak activity index) with AFO-ON. to-day walking of youth with CP is predominately at low
rates.21 Recent work has documented a positive association
between daily walking levels and intensity with mobility-
DISCUSSION based participation in daily life for youth with CP.21,23
We did not find consistently favorable community- Also, from a public health perspective, youth with CP
based walking activity outcomes for the AFO-ON regardless of GMFCS level demonstrate maximal walk-
condition compared with the AFO-OFF condition. ing activity levels that are far below those recommended
The within-subject analysis showed large variability in for overall health (60 min/day of moderately vigorous
outcomes between the 2 conditions. This variability may activity).21,24
be a function of a general lack of consistency in orthotic The orthoses worn by the children in this study were
prescription on the basis of gait pattern and biomechanical not in accord with previously published algorithms match-
impairments. This includes multiple orthoses employed ing orthoses to gait pattern.14 Our data suggest that several
for the same gait pattern, heterogeneity of the study subjects were currently wearing prescriptions that did not
sample, and/or the general population of children with CP address the segmental biomechanical limitations of their
that are ambulatory, and the lack of individualization of presenting gait pattern (S2, S6, S9, and S10). For example,
shoes and SVAs. The results of this pilot study suggest that subjects 2 and 10 with crouch gait patterns were wearing
the majority of participants were not currently wearing hinged AFOs that would be unable to limit excessive tib-
orthoses and/or footwear prescriptions that positively in- ial progression during stance. A child with a crouch gait
fluenced their daily walking activity levels or the secondary pattern, per published algorithms, should be prescribed a
outcomes of walking intensity. The 2 subjects for whom device that limits shank inclination during midstance (eg,
the SVA was explicitly optimized (1 with a shoe modified to a SAFO). Assuming that the remaining subjects (S1, S3,
have a point loading rocker) demonstrated a positive effect S4, S5, S7, S8, and S11) were wearing orthoses that had
of AFO/footwear use on daily walking levels. This positive potential to address their individual gait impairments, only
effect was also documented for the secondary outcomes of 2 participants (S3 and S11) had a greater than 1 standard
walking time and walking intensity for these 2 subjects. deviation change in walking activity levels and intensity
AFO management in CP must positively influence during the AFO-ON versus the AFO-OFF condition.
day-to-day walking activity. As compared with children Numerous authors have proposed theoretical guide-
who are TD, youth with CP take significantly fewer strides lines for the optimal SVA for standing and walking in
each day and spend less time walking.21 Relative to inten- SAFOs.25-27 These proposed recommendations range from
sity or patterns of walking, youth that are TD spend a simi- “slight incline” and “knee cap over metatarsophalangeal
lar number of strides and/or time at low (1-30 strides/min) joints” to specific ranges (eg, 7◦ -10◦ incline). In 1972,
Glancy and Lindseth,28 on the basis of visual gait analy- tional outcomes of an individualized prescription. If future
sis, proposed 3◦ to 5◦ of incline. In 1992, Hullin et al29 work confirms the influence of footwear on walking out-
proposed 0◦ with a rocker sole and 10◦ incline without a comes, fiscal and policy implications will follow because
rocker sole. Owen reported SVA tuned to optimum align- footwear is not traditionally reimbursed in some countries
ment using a video vector analysis of approximately 7◦ to (eg, the United States).
15◦ (mean 11.4◦ ).30 Most recently, Jagadamma et al31,32 Study limitations should guide the interpretation of
proposed an average SVA of 10.8◦ incline on the basis of these pilot data. First, the sample size was small and maybe
gait analysis in youth with CP. The individual SVA data under powered to find true differences between treatment
for the 4 subjects in this study wearing SAFOs (S3, S7, S8, conditions. Although the randomized cross-over design
and S11) were broader than the values reported in the lit- does somewhat mitigate this issue, a larger sample size
erature, which may have contributed to our observation of is needed to corroborate these findings. Clinical hetero-
an inconsistent positive group effect on walking activity. geneity of this study sample and the broader population
These results support the need for further research of children with CP who are ambulatory could confound
on the effect of AFO/footwear prescription relative to the the effect of AFO use on walking activity outcomes. More
gait pattern and physical and neuromotor impairments of work is needed to understand the influence of the SVA
each limb for each client. This concurs with emerging rec- and shoe modifications within orthotic management. Such
ommendations that the SVA needs to be individualized for studies would be enhanced by use of full kinetic and
each leg within each patient depending on their gait pat- kinematic analyses in addition to step activity monitor-
tern and diagnosis.33 Orthotic management also needs to ing. A key strength of this project was that the type of
account for footwear as an influencing factor in the func- monitoring used, which can be feasibly implemented in