Generic Name Indication Mechanism of Action Classification Side Effects/Adverse Drug Reactions Nursing Responsibilities

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Generic Name Indication Mechanism of Action Classification Side Effects/Adverse Nursing Responsibilities

Drug Reactions
GENERIC NAME: Serious susceptible kills bacteria by Anti-infective; Hypersensitivity to Before:
Piperacillin / infections, inhibiting the Beta-lactam penicillins, -check the doctor’s order
Tazobactam including lower synthesis of bacterial antibiotic; Anti- cephalosphorins, or -assess for history: hepatic and renal
Brand name: Zosyn respiratory tract, cell walls. It binds pseudomonal other drugs. Safety in impairment, lactation, pregnancy
intraabdominal, preferentially to penicillin children < 12 years old, -assess for physical cues: skin status,
septicemia, skin specific penicillin- pregnancy, lactation. LFTs, renal function tests, culture of
and skin structure, binding proteins affected area
bone and joint, (PBPs) located inside -Obtain specimen for culture and
UTIs, gynecological bacterial cell walls. sensitivity prior to first dose of the
infections, and drug; start drug pending results.
uncomplicated Periodic CBC with differential,
gonococcal platelet count, Hgb & Hgt, and
urethritis. serum electrolytes.

During:
-administer the right drug
-explain to the patient about the
importance and purpose of the drug
-administer at the right time and
right dosage
-avoid alcohol while taking this drug
and for 3 days after because severe
reactions often occur
-discontinue if hypersensitivity
reaction occurs

After:
-Document and record.
-Monitor for hypersensitivity
response; discontinue drug and
notify physician if allergic response
noted.
-Monitor for hemorrhagic
manifestations because high dose
may induce coagulation
abnormalities.
-Instruct family/significant others to
report significant, unexplained
diarrhea.

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