Ethylene oxide

Safety Data Sheet P-4798

This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

SECTION: 1. Product and company identification

1.1. Product identifier
Name : Ethylene oxide
CAS No : 75-21-8
Other means of identification : Dihydrooxirine, dimethylene oxide, ethene oxide, epoxyethane, oxane, oxacyclopropane,
oxidoethane, oxiran, oxirane, 1,2 epoxyethane
1.2. Relevant identified uses of the substance or mixture and uses advised against
Use of the substance/mixture : Industrial use. Use as directed.
1.3. Details of the supplier of the safety data sheet
Praxair, Inc.
39 Old Ridgebury Road
Danbury, CT 06810-5113 - USA
T 1-800-772-9247 (1-800-PRAXAIR) - F 1-716-879-2146
www.praxair.com
1.4. Emergency telephone number
Emergency number : Onsite Emergency: 1-800-645-4633

CHEMTREC, 24hr/day 7days/week

— Within USA: 1-800-424-9300, Outside USA: 001-703-527-3887
(collect calls accepted, Contract 17729)

SECTION 2: Hazard identification

2.1. Classification of the substance or mixture
GHS-US classification
Flam. Gas 1 H220
Liquefied gas H280
Acute Tox. 3 (Inhalation:gas) H331
Skin Irrit. 2 H315
Eye Irrit. 2A H319
Skin Sens. 1B H317
Muta. 1B H340
Carc. 1A H350
Repr. 1A H360
STOT SE 3 H335
STOT RE 1 H372

2.2. Label elements

GHS-US labeling
Hazard pictograms (GHS-US) :

GHS02 GHS04 GHS06 GHS07 GHS08

Signal word (GHS-US) : DANGER
Hazard statements (GHS-US) : H220 - EXTREMELY FLAMMABLE GAS
H280 - CONTAINS GAS UNDER PRESSURE; MAY EXPLODE IF HEATED
H315+H320 - CAUSES SKIN AND EYE IRRITATION
H317 - MAY CAUSE AN ALLERGIC SKIN REACTION
H331 - TOXIC IF INHALED
H335 - MAY CAUSE RESPIRATORY IRRITATION
H340 - MAY CAUSE GENETIC DEFECTS
H350 - MAY CAUSE CANCER
H360 - MAY DAMAGE FERTILITY OR THE UNBORN CHILD
EN (English US) SDS ID: P-4798 1/10

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 Ethylene oxide
Safety Data Sheet P-4798
This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

H372 - CAUSES DAMAGE TO ORGANS (NERVOUS SYSTEM, KIDNEYS) THROUGH

PROLONGED OR REPEATED EXPOSURE
CGA-HG04 - MAY FORM EXPLOSIVE MIXTURES WITH AIR
CGA-HG11 - SYMPTOMS MAY BE DELAYED
Precautionary statements (GHS-US) : P201 - Obtain special instructions before use
P202 - Do not handle until all safety precautions have been read and understood
P210 - Keep away from Heat/Open flames/Sparks/Hot surfaces. - No smoking
P260 - Do not breathe gas
P262 - Do not get in eyes, on skin, or on clothing.
P271+P403 - Use and store only outdoors or in a well-ventilated place.
P280+P284 - Wear protective gloves, protective clothing, eye protection, respiratory protection,
and/or face protection.
P377 - Leaking gas fire: Do not extinguish, unless leak can be stopped safely
P381 - Eliminate all ignition sources if safe to do so
P405 - Store locked up
P501 - Dispose of contents/container in accordance with container supplier/owner instructions.
CGA-PG05 - Use a back flow preventive device in the piping.
CGA-PG20+CGA-PG10 - Use only with equipment of compatible materials of construction and
rated for cylinder pressure.
CGA-PG12 - Do not open valve until connected to equipment prepared for use.
CGA-PG06 - Close valve after each use and when empty.
CGA-PG02 - Protect from sunlight when ambient temperature exceeds 52°C (125°F).

2.3. Other hazards

Other hazards not contributing to the : Asphyxiant in high concentrations.
classification
2.4. Unknown acute toxicity (GHS US)
No data available

SECTION 3: Composition/Information on ingredients

3.1. Substance
Name Product identifier %
Ethylene oxide (CAS No) 75-21-8 100
(Main constituent)

3.2. Mixture
Not applicable

SECTION 4: First aid measures

4.1. Description of first aid measures
First-aid measures general : IMPORTANT In all cases of exposure, get or summon medical treatment immediately. Take the
victim to a doctor or medical facility at once.
First-aid measures after inhalation : Remove to fresh air and keep at rest in a position comfortable for breathing. If breathing is
difficult, trained personnel should give oxygen.Call a physician.If not breathing, give artificial
respiration.
First-aid measures after skin contact : In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes
while removing contaminated clothing and shoes. Wash with plenty of soap and water.

The liquid may cause frostbite. For exposure to liquid, immediately warm frostbite area with
warm water not to exceed 105°F (41°C). Water temperature should be tolerable to normal skin.
Maintain skin warming for at least 15 minutes or until normal coloring and sensation have
returned to the affected area. In case of massive exposure, remove clothing while showering
with warm water. Seek medical evaluation and treatment as soon as possible.

.
First-aid measures after eye contact : Immediately flush eyes thoroughly with water for at least 15 minutes. Hold the eyelids open and
away from the eyeballs to ensure that all surfaces are flushed thoroughly. Contact an
ophthalmologist immediately.
First-aid measures after ingestion : Not expected to be a primary route of exposure. . Give water to drink if victim completely
conscious/alert. Do not induce vomiting. Call a physician. Never give anything by mouth to an
unconscious person.

EN (English US) SDS ID: P-4798 2/10

This document is only controlled while on the Praxair, Inc. website and a copy of this controlled version is available for download.
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 Ethylene oxide
Safety Data Sheet P-4798
This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

4.2. Most important symptoms and effects, both acute and delayed
No additional information available
4.3. Indication of any immediate medical attention and special treatment needed
No additional information available

SECTION 5: Firefighting measures

5.1. Extinguishing media
Suitable extinguishing media : Carbon dioxide, Dry chemical, Water spray or fog.
5.2. Special hazards arising from the substance or mixture
Fire hazard : EXTREMELY FLAMMABLE GAS.
Explosion hazard : EXTREMELY FLAMMABLE GAS. Forms explosive mixtures with air and oxidizing agents.
Reactivity : Exothermic polymerization is possible (see incompaitible materials).
5.3. Advice for firefighters
Firefighting instructions : DANGER! Cancer and reproductive hazard.

DANGER! Toxic, flammable liquefied gas

FORMS EXPLOSIVE MIXTURES WITH AIR

Evacuate all personnel from the danger area. Use self-contained breathing apparatus (SCBA)
and protective clothing. Immediately cool containers with water from maximum distance.
Remove ignition sources if safe to do so. Remove containers from area of fire if safe to do so.
On-site fire brigades must comply with OSHA 29 CFR 1910.156 and applicable standards
under 29 CFR 1910 Subpart L—Fire Protection.
Special protective equipment for fire fighters : Standard protective clothing and equipment (Self Contained Breathing Apparatus) for fire
fighters.
Other information : Containers are equipped with a pressure relief device. (Exceptions may exist where authorized
by DOT.).

SECTION 6: Accidental release measures

6.1. Personal precautions, protective equipment and emergency procedures
General measures : DANGER! Cancer and reproductive hazard. . DANGER! Toxic, flammable liquefied gas .
FORMS EXPLOSIVE MIXTURES WITH AIR. If involved in a fire, this product may emit irritating
and potentially toxic fumes. Fumes and vapors may spread from leak. Vapors are heavier than
air and may collect in low spots. Evacuate personnel to a safe area. Appropriate self-contained
breathing apparatus may be required. Approach suspected leak area with caution. Remove all
sources of ignition. if safe to do so. Reverse flow into cylinder may cause rupture. Reduce gas
with fog or fine water spray. Stop flow of product if safe to do so. Ventilate area or move
container to a well-ventilated area. Flammable gas may spread from leak. Before entering the
area, especially a confined area, check the atmosphere with an appropriate device.
6.1.1. For non-emergency personnel
No additional information available
6.1.2. For emergency responders
No additional information available
6.2. Environmental precautions
Try to stop release. Reduce vapor with fog or fine water spray. Prevent waste from contaminating
the surrounding environment. Prevent soil and water pollution. Dispose of contents/container in
accordance with local/regional/national/international regulations. Contact supplier for any special
requirements.
6.3. Methods and material for containment and cleaning up
No additional information available
6.4. Reference to other sections
See also sections 8 and 13.

EN (English US) SDS ID: P-4798 3/10

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 Ethylene oxide
Safety Data Sheet P-4798
This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

SECTION 7: Handling and storage

7.1. Precautions for safe handling
Precautions for safe handling : Prevent product contamination

Water or organic contamination may cause a violent reaction.

Do not breathe gas/vapor. Avoid all contact with skin, eyes, or clothing. Emergency eye wash
fountains and safety showers should be available in the immediate vicinity of any potential
exposure.

Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No
smoking. Use only non-sparking tools. Use only explosion-proof equipment.

Wear leather safety gloves and safety shoes when handling cylinders. Protect cylinders from
physical damage; do not drag, roll, slide or drop. While moving cylinder, always keep in place
removable valve cover. Never attempt to lift a cylinder by its cap; the cap is intended solely to
protect the valve. When moving cylinders, even for short distances, use a cart (trolley, hand
truck, etc.) designed to transport cylinders. Never insert an object (e.g., wrench, screwdriver,
pry bar) into cap openings; doing so may damage the valve and cause a leak. Use an
adjustable strap wrench to remove over-tight or rusted caps. Slowly open the valve. If the
valve is hard to open, discontinue use and contact your supplier. Close the container valve
after each use; keep closed even when empty. Never apply flame or localized heat directly to
any part of the container. High temperatures may damage the container and could cause the
pressure relief device to fail prematurely, venting the container contents. For other precautions
in using this product, see section 16.
7.2. Conditions for safe storage, including any incompatibilities
Storage conditions : Because of the potential for violent decomposition, containers of ethylene oxide must be
properly blanketed with an inert gas and given extraordinary protection against fire exposure.

Store only where temperature will not exceed 125°F (52°C). Post “No Smoking or Open
Flames” signs in storage and use areas. There must be no sources of ignition. Separate
packages and protect against potential fire and/or explosion damage following appropriate
codes and requirements (e.g., NFPA 30, NFPA 55, NFPA 70, and/or NFPA 221 in the U.S.) or
according to requirements determined by the Authority Having Jurisdiction (AHJ). Always
secure containers upright to keep them from falling or being knocked over. Install valve
protection cap, if provided, firmly in place by hand when the container is not in use. Store full
and empty containers separately. Use a first-in, first-out inventory system to prevent storing full
containers for long periods. For other precautions in using this product, see section 16.

All equipment in storage areas must be explosion-proof. Electric installation in storage areas
must meet the requirements of National Electric Code (NEC) Article 500. This material is a
static accumulator. To avoid ignition of vapors by static discharge, all metal parts and
equipment must be grounded. Follow NFPA 77, Recommended Practice on Static Electricity
(www.nfpa.org), and API Recommended Practice 2003, Protection Against Ignitions Arising Out
of Static, Lightning, and Stray Currents.

OTHER PRECAUTIONS FOR HANDLING, STORAGE, AND USE: When handling product
under pressure, use piping and equipment adequately designed to withstand the pressures to
be encountered. Never work on a pressurized system. Use a back flow preventive device in the
piping. Gases can cause rapid suffocation because of oxygen deficiency; store and use with
adequate ventilation. If a leak occurs, close the container valve and blow down the system in a
safe and environmentally correct manner in compliance with all international, federal/national,
state/provincial, and local laws; then repair the leak. Never place a container where it may
become part of an electrical circuit.
7.3. Specific end use(s)
None.

SECTION 8: Exposure controls/personal protection

8.1. Control parameters
No additional information available

EN (English US) SDS ID: P-4798 4/10

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 Ethylene oxide
Safety Data Sheet P-4798
This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

8.2. Exposure controls

Appropriate engineering controls : Use an explosion-proof local exhaust system. Local exhaust and general ventilation must be
adequate to meet exposure standards. MECHANICAL (GENERAL): Inadequate - Use only in
a closed system. Use explosion proof equipment and lighting.
Hand protection : Butyl rubber (IIR) /.
Eye protection : Select eye protection in accordance with OSHA 29 CFR 1910.133. Safety glasses with face
shield. Contact lenses should not be worn.
Skin and body protection : Wear metatarsal shoes and work gloves for cylinder handling, and protective clothing where
needed. Wear appropriate chemical gloves during cylinder changeout or wherever contact with
product is possible. Select per OSHA 29 CFR 1910.132, 1910.136, and 1910.138.

Rubber shoes and apron where risk of liquid spill exists. Select in accordance with OSHA 29
CFR 1910.132 and 1910.133.

.
Respiratory protection : When workplace conditions warrant respirator use, follow a respiratory protection program that
meets OSHA 29 CFR 1910.134, ANSI Z88.2, or MSHA 30 CFR 72.710 (where applicable).
Use an air-supplied or air-purifying cartridge if the action level is exceeded. Ensure that the
respirator has the appropriate protection factor for the exposure level. If cartridge type
respirators are used, the cartridge must be appropriate for the chemical exposure (e.g., an
organic vapor cartridge). For emergencies or instances with unknown exposure levels, use a
self-contained breathing apparatus (SCBA).
Thermal hazard protection : Wear cold insulating gloves when transfilling or breaking transfer connections.

SECTION 9: Physical and chemical properties

9.1. Information on basic physical and chemical properties
Physical state : Gas
Color : Colorless
Odor : ether-like
Odor threshold : 420 - 490 ppm
pH : Not applicable.
Relative evaporation rate (butyl acetate=1) : No data available
Relative evaporation rate (ether=1) : Not applicable.
Melting point : No data available
Freezing point : No data available
Boiling point : 10.5 °C (51.26 °F)
Flash point : -20 °C (-4 °F)
Critical temperature : 195.8 °C
Auto-ignition temperature : 429 °C (804 °F)
Decomposition temperature : No data available
Flammability (solid, gas) : 3 - 100 vol %
Vapor pressure : 1.5 bar (22 psia) (at 20°C (68°F))
Relative vapor density at 20 °C : No data available
Relative density : 0.87 (Water = 1) (at 4°C (39.2°F))
Density : 1.824 kg/m³ (0.1139 lb/ft3) (at 21.1 °C (70 °F))
Relative gas density : 1.52 (Air = 1) (at 21.1 °C (70 °F))
Solubility : Water: No data available
Log Pow : Not applicable.
Log Kow : Not applicable.
Viscosity, kinematic : Not applicable.
Viscosity, dynamic : Not applicable.
Explosive properties : Forms explosive mixtures with air and oxidizing agents.
Oxidizing properties : None.

EN (English US) SDS ID: P-4798 5/10

This document is only controlled while on the Praxair, Inc. website and a copy of this controlled version is available for download.
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 Ethylene oxide
Safety Data Sheet P-4798
This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

Explosion limits : No data available

9.2. Other information
No additional information available

SECTION 10: Stability and reactivity

10.1. Reactivity
Exothermic polymerization is possible (see incompaitible materials).
10.2. Chemical stability
Stable under normal conditions.
10.3. Possibility of hazardous reactions
May occur.
10.4. Conditions to avoid
Contamination, especially by incompatible materials (see 10.5). Heat. Sparks. Ignition sources.

Pure ethylene oxide decomposes violently if exposed to a high enough temperature. The temperature required for decomposition can vary depending on
time, pressure, and conditions within the system and is reduced as pressure and volume-to-surface ratios are increased. Decomposition temperatures
ranging from 842ºF-1040ºF (450ºC-560ºC) have been observed in experimental apparatus.

.
10.5. Incompatible materials
Oxidizing agents. Mercaptans. Alcohols. Alkali metals, Alkaline earth metals, Acetylide forming metals, Chromium, Titanium > 1022°F (550°C), Uranium
(U) > 1382°F (750°C), Magnesium > 1427°F (775°C). . Will polymerize violently if contaminated with:. Amines. alkalis. Acids. Mineral acids. Metal
chlorides. Metal oxides. Water. Organic materials.
10.6. Hazardous decomposition products
Carbon dioxide. Carbon monoxide.

SECTION 11: Toxicological information

11.1. Information on toxicological effects

Acute toxicity : Inhalation:gas: TOXIC IF INHALED.

Ethylene oxide ( \f )75-21-8
LC50 inhalation rat (ppm) 2920 ppm/1h
ATE US (gases) 1460.000 ppmV/4h

Skin corrosion/irritation : CAUSES SKIN IRRITATION.

pH: Not applicable.
Serious eye damage/irritation : CAUSES SERIOUS EYE IRRITATION.
pH: Not applicable.
Respiratory or skin sensitization : MAY CAUSE AN ALLERGIC SKIN REACTION.
Germ cell mutagenicity : MAY CAUSE GENETIC DEFECTS.
Carcinogenicity : MAY CAUSE CANCER.
Ethylene oxide (75-21-8)
IARC group 1 - Carcinogenic to humans
National Toxicology Program (NTP) Status 2 - Known Human Carcinogens
Reproductive toxicity : MAY DAMAGE FERTILITY OR THE UNBORN CHILD.
Specific target organ toxicity (single exposure) : MAY CAUSE RESPIRATORY IRRITATION.
Specific target organ toxicity (repeated : CAUSES DAMAGE TO ORGANS (NERVOUS SYSTEM, KIDNEYS) THROUGH PROLONGED
exposure) OR REPEATED EXPOSURE.
Aspiration hazard : Not classified

EN (English US) SDS ID: P-4798 6/10

This document is only controlled while on the Praxair, Inc. website and a copy of this controlled version is available for download.
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 Ethylene oxide
Safety Data Sheet P-4798
This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

SECTION 12: Ecological information

12.1. Toxicity
No additional information available
12.2. Persistence and degradability
Ethylene oxide (75-21-8)
Persistence and degradability No ecological damage caused by this product.

12.3. Bioaccumulative potential

Ethylene oxide (75-21-8)
Log Pow Not applicable.
Log Kow Not applicable.
Bioaccumulative potential No ecological damage caused by this product.

12.4. Mobility in soil

Ethylene oxide (75-21-8)
Mobility in soil No data available.

12.5. Other adverse effects

Effect on ozone layer : None.

SECTION 13: Disposal considerations

13.1. Waste treatment methods
Waste disposal recommendations : Do not attempt to dispose of residual or unused quantities. Return container to supplier.
Additional information : This chemical is a pesticide product registered by the United States Environmental Protection
Agency and is subject to certain labeling requirements under federal pesticide law. These
requirements differ from the classification criteria and hazard information required for safety
data sheets (SDS), and for workplace labels of non-pesticide chemicals. The hazard
information required on the pesticide label is reproduced below. The pesticide label also
includes other important information, including directions for use.

STORAGE AND DISPOSAL:

Do not contaminate water, food, or feed by storage and disposal.
Pesticide Storage: Cylinders should be stored in a well ventilated area.
Pesticide Disposal: Return cylinder with residual product to supplier.
Container Handling: Do not reuse this container for any other purpose. Do not refill this
cylinder; return to supplier.

SECTION 14: Transport information

In accordance with DOT
Transport document description : UN1040 Ethylene oxide (up to a total pressure of 1MPa (10 bar) at 50 degrees C), 2.3
UN-No.(DOT) : UN1040
Proper Shipping Name (DOT) : Ethylene oxide
up to a total pressure of 1MPa (10 bar) at 50 degrees C
Transport hazard class(es) (DOT) : 2.3 - Class 2.3 - Poisonous gas 49 CFR 173.115
Hazard labels (DOT) : Poison Gas
2.3 - Poison gas
2.1 - Flammable gas

EN (English US) SDS ID: P-4798 7/10

This document is only controlled while on the Praxair, Inc. website and a copy of this controlled version is available for download.
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 Ethylene oxide
Safety Data Sheet P-4798
This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

DOT Special Provisions (49 CFR 172.102) : 4 - This material is poisonous by inhalation (see 171.8 of this subchapter) in Hazard Zone D
(see 173.116(a) of this subchapter), and must be described as an inhalation hazard under the
provisions of this subchapter.
342 - Glass inner packaging (such as ampoules or capsules) intended only for use in
sterilization devices, when containing less than 30 mL of ethylene oxide per inner packaging
with not more than 300 mL per outer packaging, may be transported in accordance with
§173.4a of this subchapter, irrespective of the restriction of §173.4a(b) provided that: a. After
filling, each glass inner packaging must be determined to be leak-tight by placing the glass
inner packaging in a hot water bath at a temperature and for a period of time sufficient to
ensure that an internal pressure equal to the vapor pressure of ethylene oxide at 55 °C is
achieved. Any glass inner packaging showing evidence of leakage, distortion or other defect
under this test must not be transported under the terms of this special provision;b. In addition to
the packaging required in §173.4a, each glass inner packaging must be placed in a sealed
plastic bag compatible with ethylene oxide and capable of containing the contents in the event
of breakage or leakage of the glass inner packaging; andc. Each glass inner packaging is
protected by a means of preventing puncture of the plastic bag (e.g., sleeves or cushioning) in
the event of damage to the packaging (e.g., by crushing).
T50 - When portable tank instruction T50 is referenced in Column (7) of the 172.101 Table, the
applicable liquefied compressed gases are authorized to be transported in portable tanks in
accordance with the requirements of 173.313 of this subchapter.
TP20 - This hazardous material must only be transported in insulated tanks under a nitrogen
blanket.
Additional information
Other information : No supplementary information available.
Special transport precautions : Avoid transport on vehicles where the load space is not separated from the driver's
compartment. Ensure vehicle driver is aware of the potential hazards of the load and knows
what to do in the event of an accident or an emergency. Before transporting product containers:
- Ensure there is adequate ventilation. - Ensure that containers are firmly secured. - Ensure
cylinder valve is closed and not leaking. - Ensure valve outlet cap nut or plug (where provided)
is correctly fitted. - Ensure valve protection device (where provided) is correctly fitted.

Transport by sea
UN-No. (IMDG) : 1040
Proper Shipping Name (IMDG) : ETHYLENE OXIDE
Class (IMDG) : 2 - Gases

Air transport
UN-No. (IATA) : 1040
Proper Shipping Name (IATA) : Ethylene oxide
Class (IATA) : 2

SECTION 15: Regulatory information

15.1. US Federal regulations
Ethylene oxide (75-21-8)
Listed on the United States TSCA (Toxic Substances Control Act) inventory

Subject to reporting requirements of United States SARA Section 313

RQ (Reportable quantity, section 304 of EPA's 10 lb
List of Lists)
SARA Section 302 Threshold Planning Quantity 1000 lb
(TPQ)
SARA Section 311/312 Hazard Classes Delayed (chronic) health hazard
Fire hazard
Immediate (acute) health hazard
Reactive hazard
Sudden release of pressure hazard

15.2. International regulations

CANADA

EN (English US) SDS ID: P-4798 8/10

This document is only controlled while on the Praxair, Inc. website and a copy of this controlled version is available for download.
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 Ethylene oxide
Safety Data Sheet P-4798
This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

EU-Regulations

15.2.2. National regulations

Ethylene oxide (75-21-8)
Listed on IARC (International Agency for Research on Cancer)
Listed as carcinogen on NTP (National Toxicology Program)

15.3. US State regulations

Ethylene oxide(75-21-8)
U.S. - California - Proposition 65 - Carcinogens List Yes
U.S. - California - Proposition 65 - Developmental Yes
Toxicity
U.S. - California - Proposition 65 - Reproductive Yes
Toxicity - Female
U.S. - California - Proposition 65 - Reproductive Yes
Toxicity - Male
Non-significant risk level (NSRL) 20
State or local regulations U.S. - Massachusetts - Right To Know List
U.S. - New Jersey - Right to Know Hazardous Substance List
U.S. - Pennsylvania - RTK (Right to Know) List

SECTION 16: Other information

Other information : When you mix two or more chemicals, you can create additional, unexpected hazards. Obtain
and evaluate the safety information for each component before you produce the mixture.
Consult an industrial hygienist or other trained person when you evaluate the end product.
Before using any plastics, confirm their compatibility with this product.

Praxair asks users of this product to study this SDS and become aware of the product hazards
and safety information. To promote safe use of this product, a user should (1) notify
employees, agents, and contractors of the information in this SDS and of any other known
product hazards and safety information, (2) furnish this information to each purchaser of the
product, and (3) ask each purchaser to notify its employees and customers of the product
hazards and safety information.

The opinions expressed herein are those of qualified experts within Praxair, Inc. We believe
that the information contained herein is current as of the date of this Safety Data Sheet. Since
the use of this information and the conditions of use are not within the control of Praxair, Inc., it
is the user's obligation to determine the conditions of safe use of the product.

Praxair SDSs are furnished on sale or delivery by Praxair or the independent distributors and
suppliers who package and sell our products. To obtain current SDSs for these products,
contact your Praxair sales representative, local distributor, or supplier, or download from
www.praxair.com. If you have questions regarding Praxair SDSs, would like the document
number and date of the latest SDS, or would like the names of the Praxair suppliers in your
area, phone or write the Praxair Call Center (Phone: 1-800-PRAXAIR/1-800-772-9247;
Address: Praxair Call Center, Praxair, Inc., P.O. Box 44, Tonawanda, NY 14151-0044).

PRAXAIR and the Flowing Airstream design are trademarks or registered trademarks of Praxair
Technology, Inc. in the United States and/or other countries.

EN (English US) SDS ID: P-4798 9/10

This document is only controlled while on the Praxair, Inc. website and a copy of this controlled version is available for download.
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 Ethylene oxide
Safety Data Sheet P-4798
This SDS conforms to U.S. Code of Federal Regulations 29 CFR 1910.1200, Hazard Communication.
Date of issue: 01/01/1982 Revision date: 10/26/2015 Supersedes: 07/09/2015

NFPA health hazard : 3 - Short exposure could cause serious temporary or

residual injury even though prompt medical attention was
given.
NFPA fire hazard : 4 - Will rapidly or completely vaporize at normal pressure
and temperature, or is readily dispersed in air and will burn
readily.
NFPA reactivity : 3 - Capable of detonation or explosive reaction, but
requires a strong initiating source or must be heated under
confinement before initiation, or reacts explosively with
water.

HMIS III Rating

Health : 1 Slight Hazard - Irritation or minor reversible injury possible
Flammability : 4 Severe Hazard
Physical : 3 Serious Hazard

SDS US (GHS HazCom 2012) - Praxair

This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as
guaranteeing any specific property of the product.

EN (English US) SDS ID: P-4798 10/10

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Praxair cannot assure the integrity or accuracy of any version of this document after it has been downloaded or removed from our website.