Vaccine Classification Derived from Schedule Interval Dose Dosage Route Site Adverse effects Contraindications Notes

BCG Live attenuated Mycobacterium Birth (within first - 1 0.05 newborn ID Deltoid Normal: Scarring Impaired immunity PPD recommended prior if:
bacteria bovis 2 months) 0.1 school Immunosuppressive 1. Suspected congenital TB
entrance Non-healing ulcers therapy 2. Hx of close contact to
Hypertrophy/suppuration Pregnant women infectious TB
of lymph nodes 3. Clinical findings
suggestive of TB and/or CXR
of TB
Hepatitis B Inactivated Inserting Birth 3 0.5 mL IM Upper outer Pain at site Anaphylaxis to yeast If (+) mother: give HBV and
plasmid that portion of Fatigue, headache, HBIG (0.5) within 12 hours
contains the 0- 1to 2- 6 to 18 thigh irritability Ok for pregnant and of life. HBIG should be
gene for HBsAg months immunodeficient. administered not later than
into the 7 days of age, if not
common Dose at birth is immediately available. Last
baker’s yeast not counted dose given at 6 months old.
(Saccharomyces
cerevisiae), If (-) mother: give HBV at 30
which then days, regardless of weight.
produce HBsAg.
DPT Inactivated 6-10-14 1 month 3-5 0.5 mL IM Upper outer Erythema, induration Anaphylaxis Delay in children with
4th: 12 months 6 months from portion of Palpable nodes Encephalopathy not due neurologic condition until
(minimum) or on 3rd dose thigh Abscess at site to other causes within 7 stable
4th birthday (best) Fever days after vaccination
5th dose: 4-6 years Needed if 4th Arthus-type reaction (no Family history of seizures,
old dose given more booster for less than Precaution for DTaP: neuro disorders are NOT
before 4th 10 years apart) 40.5⁰C or higher contraindications
birthday Brain damage Hypotonic,
Encephalopathy hyporesponsive episode NOT a
Convulsions Persistent, inconsolable precaution/contraindication
crying for 3 hours or for Tdap:
Severe: anaphylaxis, longer 40.5⁰C or higher
urticaria Convulsions within 3 days Hypotonic, hyporesponsive
episode, persistent,
Precaution for Tdap: inconsolable crying for 3
Moderate or severe acute hours or longer, convulsions
illness during childhood
History of GBS within 6 immunization
weeks after dose of TT within 3 days
Progressive neurologic Stable neurologic disorder
disorder Pregnancy
Breastfeeding
Immunosuppression
Measles/ MMR Live attenuated Chick embryo Measles: 1 month 2-3 Fever (7-12 days after) Anaphylaxis MAY BE GIVEN to children
fibroblast 9-12 months Transient rashes (7-10 Immunosuppressed allergic to eggs
culture Outbreak: 6 days after) Pregnant
months Wheal, flare at site

If 1st dose was at

12 months, 2nd
dose is at 4-6
years old

If 1st dose was

before 12 months,
revaccinate with 2
additional doses
(at 12 months and
4-6 years old)

MMR: 3 months
12 months to 12
years
1st dose: 12-47
months
2nd: 4-6 years

OPV Live attenuated 6-10-14 weeks 4 weeks 3-4 2-3 drops PO Mouth Vaccine associated Anaphylaxis Replicate in the intestinal
paralytic poliomyelitis Immunodeficiency mucosa, lymphoid cells and
4th dose: given if nodes that drain into the
3rd dose of OPV Vaccine-derived poliovirus Avoided unless outbreak: intestine.
was before 4th Pregnant
birthday. At 4-6 Shed in the stool for up to 6
years old weeks after. Maximum
shedding at 2 weeks

Not used to vaccinate

household contacts of
immunodeficient patients.
IPV Inactivated 6-10-14 4 weeks 4 IM Pain, redness Anaphylaxis Less protection to
Pregnant unimmunized persons
4th dose: given if Risk for wild polio through herd immunity
3rd dose of IPV Lower intestinal immunity
was before 4th Costs more than OPV
birthday. At 4-6 Requires injection
years old
Only vaccine recommended
for vaccination of
 immunodeficient persons
and household contacts.
Haemophilus Inactivated 6-10-14 4 weeks 3 IM Swelling, redness, pain Anaphylaxis NOT GIVEN AFTER 59
Influenzae Type Younger than 6 weeks MONTHS unless high risk
B Vaccine Booster: 12-15 6 months from Fever, irritability (immunologic tolerance)
months of age 3rd dose (infrequent)

Delayed in moderate or
severe acute illness

Rotavirus Live attenuated RV1: 6-10 4 weeks 2 PO Anaphylaxis (latex for

Max age: 24 monovalent)
weeks
Do not vaccinate if at
RV5: 6-10-14 4 weeks 3 hospital. SHEDDING
Max age: 32 occurs.
weeks

Rabies:

Yellow fever: allergy to eggs

Japanese encephalitis: allergy to rodents