Organism : Causitive Disease Virulence factor Isolation Treatment of

agent choice

Bacillus anthracis In animals : Anthrax Virulence factor BAP 24hrs Penicillin or

Px01 –codes B. anthracis- non doxycyclin
forsynthesis of hemolytic/ judge’s wig
exotoxin appearance.
Px02- synthesis of Antracoids- tends to be
capsule hemolytic

In man: Pulmunary
anthrax or
woolsorters disease

Paenibacillus larvae American foul

spp . Larva brood

Clostridium Botulism AKA: C. botulinum – Clostridium ISOLATION:

botulinum Lamziekte or Lame A,B,E,F – more anaerobic incubator
disease susceptible in incube into BAP.
Char by : Flaccid human
paralysis C.botulinum -C, D - For maintenance : COOK
more susceptible MEAT MEDIA, BRAIN
cattle. HEART MEDIA OR
Botulinum B,D,F and THIOGLYCOLATE
G- cleaves MEDIUM
SYNAPTOBREVIN
Botulinum A and E (
most common)-
targets or cleaves
SNAP 25
Botulinum C- cleaves
SYNTAXIN
Snare proteins-
responsible for
docking of vesicle
into axonal
membrane to release
neurotrans

1
Clostridium tetani Tetanus/continuou Synaptobrevin
s contraction prevent the docking
of the vcesicle
containing Inhibitory
neuron.
Tetanus toxin-
cleaves between the
76 glutamin and 77
phenylalanina

Clostridium chauvoei Black leg

C. Hemolyticum Bacillary
hemoglobinuria or
red water

Clostridium. Novyi Gas gangrene

type A

Clostridium novyi Black disease or

type B infections necrotic
hepatitis

Clostridium Hemorrhagic
perfringens enterotoxemia or
STRUCK. Effect is
more manifested in
the intestine

Clostridium septicum Mallignant Edema

aka: cold weather
disease in sheep
Clostridium difficle Hemorrhagic
necrotizing
enterocolitis
Staphylococcus Botryomyocis in  TSST 1  BAP + 15mg Vancomycin-
aureus equine  Exofoliatin nalidixic remaining
Bumbe foot in fowl (epidermolytic acid/10mg useful
toxin) causes collistin antibiotic.
‘SSSS”  MSA
 Staphylokinase  Baird parker
caises lysis of agar
clot
 Staphyloferrib
B – resp for iron
acquisition rom
extracellular
sour
 Coagulase-
clumping
factor,
identifies
pathogenis
species
 Protein A
2
Staph aureus sp. CATALASE
Anerobius and S. NEGATIVE staph
saccharolyticus
Staphylococcus Exudative
hyicus epidermitis in
porcine
S. intermedius Pyoderma – canine
Staphylococcu. Purulent skin lx
Delphini
S. schleiferi ssp Canine – otitis
coagulans externa
Streptococcus Pharyngotonsilitis, M-protein- they can Examination: Gram
Pyogens pyoderma, mask the C3b stain and milk smear by
erysipelas, component of the newmans staining.
purpureal fever, complement. Cultivation: NA, blood
rheumatic fever, *weakest point of agar, Edwards medium.
mastitis the organism. Most pyogenic bacteria
Pneumolysin – the produce Beta hemolysis.
target is respiratory.
Erythrogenic toxin
will have the effect
on the permeability
of the Blood vessels.
Also responsible for
rash in scarlet fever.
*Streptolysin O-It
causes deep
hemolysis on BAP
*Streptolysin S- It
cause beta
hemolysis on
surface of BAP

Causitive agent Disease Virulence factor Isolation Treatment of

choice
S. Agalactiae Mastitis
S. equi ssp equi Strangles in horses
S. dysgalactiae Lamb polyarthritis
S. bovis Lactic acidosis
S. porcinus Jowl abscess
S. canis Pyogenic conditions,
lymphadenitis
S. suis Neonatal
infections,
septicemia
S. uberis Mastitis
S.pneumoniae Pneumonia,
septicemia
Erysipelothrix Polyarthritis in Neuraminidase Direct exam: Gram stain Penicillin for 5
rhusiopathiae lambs and calves Hyaluronidase Culture: days in acute
 5 to 10% form.
growth is best
on media
supplemented
with glucose or
enriched with
blood or serum
 Selective media
containing
aminoglycoside
and
3
 vancomycin
Gelatin medium 3-5 days
will produce pipe
cleaner/test tube brush
browth
TSI – A/A or acid over
acid
E. rhusiopathiae Erysipeloid in
humans
E. rhusiopathiae Erysipelas Pigs,
turkeys, marine,
mammals, dogs and
cats
Corynebacterium Skin scalding Facultatively Tinsdale agar, Cystine-
minitissimum syndrome intracellular parasite tellurite blood agar
Leukotoxic
C. renale Pizzle rot
C.pseudotuberculosis Ulcerative
lymphangitis
Caseous
lymphandenitis in
sheep and goat/
breast bone fever or
pigeon fever

Arcano bacterium Summer mastitis

pyogens
Rhodococcus equi Foal pneumonia
Leptospira Weil’s disease
interrogans serotype
icterohemorrhagiae
Leptospirosis in Moon blindness or
horses is known as periodic opthalmia
Leptospirosis in Suttgart disease
humian
Borellia anserine Fowl spirochetes Alwasys arthrioid Barbour stonner Kelly Penicillin, tetra,
borne usually thicks medium tylosine
Borellia burgdorferi Lyme disease
Borellia garinaii Lyme disease in
Europe
Borellia afzelii and Lyme disease in asia
japonica
Borellia thelleri Fever, septicemia
Borellia recurrentis Relapsing fever in
man
Brachyspira Swine dysentery Metronidazole
hyodysenteriae as preventive
Treponema Vent disease
paraluiscuniculi
T. pallidum spp Syphilis- manifested
pallidum by foul smell of
discharge and
vesicles in the
genital area
T. pallidum spp Yaws in man
pertenue
Pasteurella multocida Hemorrhagic Leukotoxin Media for isolation Management
Type B septicemia in Asia RTX toxin- glycin rich Casein sucrose yeast and vaccination
Dermonecrotoxin agar containing 5%
AKA osteolytic toxin- blood or serum
responsible for the
damage on the
4
 turbinates of pigs
being infected by
P.multocida
P. multocida Type E Hemorrhagic
septicemia in Africa
Pateurella multocida Fowl cholera and
type A snuffles in rabbit
P. multocida type D Atrophic rhinitis
and Bordetella
bronchiseptica
Mannheimia Blue bag in Ewe
hemolytica
Riemerella New duck disease
anatipestifer or aka Duck plague or
Pasteurella Infectious serositis
anatipestifer of ducks
Hemophilus parasuis Glasser’s disease Chocolate agar in 5-10%
C02 at 35-37 deg for 16-
47 hrs for X and V factor
of V factor alone
Blood agar inc in 5-10%
co2 at 35-37 deg C for
16-48 hrs if only
requiring X factor.
Avibacterium Infectious coryza-
paragallinarum severe respiratory
disorder
characterized by
swelling of the face
and almond shape
eyes.
Histophilus somnus Thromboembolic
meningoencephaliti
s
Actinobacillus Contagious Grows well on chocolate Penicillin, tetra,
pleuropneumoniae pleuropneumonia- agar and is V factor ceftiofur,
manifested by aute dependent genta,kana,
respiratory infection 5% horse tryptose agar- tmps
with high borbidity umbonate with
and mortality. transparent periphery
and grayish center
Actinobacilllus Wooden tongue
lignieresii
A. salpingitidis Salpingitis
Hemolytic in sheep
BAP
A. equuli Sleep foal or Navel
join
A. equuli ssp equuli Sleepy foal disease
A. equuli spp. Navel ill or joint ill
Hemolyticus

A. suis, A. equuli, A Posses genes

lignieresii encoding an RTX
membrane active
toxin
A. suis Alpha hemolysis in
HORSE BAP and
beta hemolysis in
SHEEP BAP
Causes fatal acute
septicemia in piglets
1-8
5
A. seminis Non-hemolytic and
no growth on MCA
Taylorella. Contagious equine
Equigenitalis metritis

Pseudomonas of VET Pyocyanin Centrimide agar

Impt Phosphorylase C Any media containing
Rhamnolipid glycerol

P. aeruginosa Suppurative
infection/ Fleece
rot
Burkholderia mallei Ganders or Equine
Farcy
B. pseudomallei aka Melioidosis
Bacillus of whitmore
Pseudimonas Tail/ Fin rot
fluorescens
Brucella of vet imp Sulfohydryl protease Tryptose CV agar
Erythritol- growth Potato dextrose agar
stimulant for B. Albimi agar
abortus, B. suis, B.
melitensis
B. abortus Fistulous withers,
poll evil
Melitensis,suis, canis, Abortion
ovis, neotomae
Bacteroides of vet
impt
B. nodosus Contagious foot root
Bacteroides. Osteomyelitis
Asaccharolyticus
B. levii Sumer mastitis
Dichelobacter Foot rot
nodosus
Fusobacterium Thrush – in horses Pili Schaelder-wilkin
necrophorum ssp Bull nose – in Endotoxin anaerobic broth
necrophorum or porcine Neuraminidase BHI + Vit K for the
biotype A ( most Avian diphtheria- in isolation of B.
virulent) fowl melaninogenicus
Port A cul medium
Fusobacterium Non pathogenic
necrophorum ssp
fundiliforme or
biotype B
Fusobacterium Avirulent
pseudonecrophorum
or type C
Salmonella O antigen: somatic SS-agar
H antigen: flagellar XLD
Vi-virulence: found
only in S. typhi
Salmonella typhi Typhoid fever Shiga like cytotoxin
Salmonella invasion
protein gene
Plasmid encoded
fimbria
Salmonella Button ulcers
cholerasuis Enteritis
pneumonia
Salmonella pullorum Bacillary white
diarrhea

6
Salmonella Fowl typhoid
gallinarum
Salmonella paratyphi Parathypoid fever
Salmonella anatum Keel disease
Yersinia pestis Bubonic plague or
black death in man
Y. enterocolitica Terminal ileitis with
diarrhea,
mesenteric adenitis
Colony may look like
“bulls eye”
Shigella dysenteriae Bacillary dysentery Have the same Salmonella- shigella agar
in man manifestation of the
E.coli pathotype EIEC
Dermatophilus Cutaneous
congolensis streptothricosis in
cattle,horse, sheep
and goat
Cutaneous
streptotrichosis in
horses is known as
RAIN SCALD
CS in sheep is
known as
STRAWBERRY foot
roit
Lumpy wool
Bordetella Dermonecrotoxin Bordet-gengou agar : Tetra,chloram,
Adenylate cyclase has mercury droplet erythrp,strepto
appearance ,sulfo
Bordetella pertussis Whooping cough
B. parapertussis Parapertussis
B. avium Rhinotracheitis in
poultry

Francisella Glucose-cystein blood Strep for

agar- produce minute humans, tetra
dewdrop like colonies for animals
Francisella Tularemia Shares antigen with
tularenesis Type A( biovar B. abortus
tularensis): in north
America
Type B( biovar
paleartia) –world
wide less virulent
Listeria Leucine rich repeats Collistin nallidixic acid
 Facultative agar
intracellular BHI ( medium of choice)
parasite LURIA BROTH
 Hemolysin
Increase in number
of monocytes vs
other bacteria :
neutrophils
L. monocytogenes Circiling disease
L. ivanovii Abortion
Moraxella bovis Infectious boving May dermonecrotic Any medium containing TETRACYCLINE
keratoconjunctivitis toxin din blood or serum
BAP 35 deg.

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8
 REPORTS

Actinomyces bovis Lumpy jaw

Bartonella henselae Cat scratch disease
B. Quintana Trench fever
B. bacilliformis Oraya fever
Anaplasma platys Canine cyclic *lumabas sa Most effective
erlichiosis or Canine modified. treatment of anaplasma
aerlichia ANaplasmosis : tetracycline
anaplasmosis incubation period
comprises the time
from introduction of
the agent into a
susceptible animal
until 1% of the RBC
are parasitized.
Developmental –
15% of rbc

Erlichia . ruminatium Heart water disease

E. ondiri Bovine petechial
fever
E. ewingii Primarily infects
neutrophils and
eosinophils
E. chffeensis Primarily infects
mononuclear
leukocytes
E. canis Primarily infects
MONONUCLEAR
cells
Coccidioides immitis Desert fever or San
Joaquin valley fever
Histoplasma Histoplasmosis
capsulatum
Aspergillus spp/ Aflatoxicosis caused
aflatoxins by mycotoxinds
produced by
Aspergillus spp.

Ocharatoxin Balkan endemic

nephropathy in
human.
Porcine
nephropathy in
swine.
Claviceps purpurea Ergot
Mycoplasmosis Infectious synovitis Mycoplasma agar-
synoviae fried egg
appearance.
Mycoplasmosis Contagious BOVINE
mycoides ssp PLEUROPNEUMONI
mycoides A
M. capricolum Contagious Caprine
pleuropneumonia
M.hyopneumonia Porcine enzootic 9
pneumonia
M. meleagridis Air sacculitis
Spiroplasma citri Citrus stubborn
Spiroplasma Pathogens of honey
melliferum bees
Mycoplasma suis Hemolytic anemia
(syn. Eperythrozoon Or Porcine
suis) eperythrozoonosis or
icteroanemia
Mycoplasma ovis ( Hemolytic anemia
syn. Eperythrozoon Ovine and caprine
ovis) e[erythrozoonosis
Mycoplasma Feline infectious
haemofelis anemia

Chlamydia psittaci Psittacosis:

Ornithosis

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