Pathophysiology: Decrease Bile Acid Synthesis

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PATHOPHYSIOLOGY

Decrease bile acid synthesis

Increased cholesterol synthesis in the liver

Supersaturation of bile with cholesterol

Formation of precipitates

Gallstones (Cholelithiasis)

Pressure Obstruction

Bile Stasis

Dec Fat Emulsification Inflammation Dec. Bile to colon Inc. S. Bilirubin Infection
Fat Intolerance Pain (RUQ) Alcoholic stool Jaudice Cholecyctitis
Weight Loss Fever Dec. Vit. K absorp Pruritus Pacreatitis
Gaseous Eructation Leukocytosis Tea-colored urine
Flatulence
Steatorrhea

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