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    Algoritma Statin

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    Agnes Irene Zagoto
    The document provides major recommendations for statin therapy for atherosclerotic cardiovascular disease prevention from the 2013 ACC/AHA guidelines. It recommends high or moderate intensity statins depending on factors like age and disease risk. It also provides dosing guidance for high and moderate intensity statins.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Algoritma Statin

    Uploaded by

    Agnes Irene Zagoto
    304 views1 page
    The document provides major recommendations for statin therapy for atherosclerotic cardiovascular disease prevention from the 2013 ACC/AHA guidelines. It recommends high or moderate intensity statins depending on factors like age and disease risk. It also provides dosing guidance for high and moderate intensity statins.

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    Algoritma statin

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    The document provides major recommendations for statin therapy for atherosclerotic cardiovascular disease prevention from the 2013 ACC/AHA guidelines. It recommends high or moderate intensity statins depending on factors like age and disease risk. It also provides dosing guidance for high and moderate intensity statins.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    304 views1 page

    Algoritma Statin

    Uploaded by

    Agnes Irene Zagoto
    The document provides major recommendations for statin therapy for atherosclerotic cardiovascular disease prevention from the 2013 ACC/AHA guidelines. It recommends high or moderate intensity statins depending on factors like age and disease risk. It also provides dosing guidance for high and moderate intensity statins.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 1

    Major Recommendations for Statin Therapy for

    Guidance for High-Intensity and


    Atherosclerotic Cardiovascular Disease Prevention Moderate Intensity Statin Dosing
    2013 ACC/AHA Blood Cholesterol Guideline
    Patients over 21 years old and High-Intensity Statins
    candidate for statin therapy • Atorvastatin 40-80 mg
    • Rosuvastatin 20-40 mg

    Moderate-Intensity Statins
    Clinical
    Yes Age ≤ 75 and Yes High-Intensity Statin • Atorvastatin 10–20 mg
    atherosclerotic
    candidate for high- Daily dose lowers LDL-C • Rosuvastatin 5–10 mg
    cardiovascular
    intensity statin by approx ≥ 50%
    disease • Simvastatin 20–40 mg
    • Pravastatin 40–80 mg
    No Moderate-Intensity Statin
    No Daily dose lowers LDL-C • Lovastatin 40 mg
    by approx 30-50% • Fluvastatin XL 80 mg
    • Fluvastatin 40 mg bid
    Yes • Pitivastatin 2–4 mg
    LDL-C ≥ 190 mg/dl High-Intensity Statin

    Yes Patients over age 75


    High-Intensity Statin
    No For patients with clinical CVD, moderate-to-high
    intensity statins if tolerated.
    For all other indications, consider comorbidities,
    Type 1 or 2 Yes Estimated 10 yr No safety, and priorities of care before initiating or
    Diabetes atherosclerotic CVD Moderate-Intensity Statin
    age 40-75 risk ≥ 7.5% continuing statin therapy.
    Calcium Scoring Considerations
    For individuals at intermediate risk (5%-7.5%) or
    No
    those who are unsure about their risk, consider
    calcium scoring.
    Age 40-75 A CAC score of zero is associated with a very low
    Estimated 10 yr Yes Moderate-to-High- CVD event rate and those individuals are unlikely to
    atherosclerotic CVD Intensity Statin benefit from statin therapy.*
    risk > 7.5%
    A CAC score ≥100 is associated with an elevated
    risk of a CVD event (> 20%) regardless of traditional
    No Algorithm adapted from Stone NJ, et. al. 2013 ACC/AHA guideline
    risk factors.*
    on the treatment of blood cholesterol to reduce atherosclerotic
    If risk is 5-7.5%, consider moderate
    cardiovascular risk in adults: a report of the American College of Online CVD Risk Calculator
    Cardiology/American Heart Association Task Force on Practice
    intensity statin if: LDL > 160 mg/dl, Guidelines. Circulation 2013; 0000437738.63853.7a
    Go to www.heart.org and search “cv risk calculator”
    family history, hs CRP > 2, CAC>300 for online web application.
    *Calcium scoring considerations are provided by Minneapolis Heart
    or 75%, ABI < .9, or high lifetime risk. Institute® and are not part of the official ACC/AHA Guidelines.

    Minneapolis Heart Institute®


    mplsheart.com Center for Preventive Cardiology
    S413160 20871 0714 ©2014 ALLINA HEALTH SYSTEM. TM A TRADEMARK
    OF ALLINA HEALTH SYSTEM. MINNEAPOLIS HEART INSTITUTE® AND
    612-863-3900
    MHI® ARE TRADEMARKS OF MINNEAPOLIS HEART INSTITUTE®, INC.

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