DRUG NAME ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING

RESPONSIBILITY

Gentamicin Interferes with Treatment on serious History of CNS: neuromuscular  Assess for
protein synthesis in infections hypersensitivity to or blockade: skeletal previous
Drug Class.: bacterial cell by toxic reaction with muscle weakness, sensitivity
Antiinfective, binding to ribosomal any aminoglycoside apnea, respiratory reaction
aminoglycoside subunit, causing antibiotic. paralysis (high doses);  Assess signs and
antibiotic misreading of genetic arachnoiditis symptoms of
code; inaccurate (intrathecal use). infection:
Dosage: peptide sequence sputum, urine,
15mg OD, IV forms in protein CV: hypotension or stool, WBC
chain, causing cell hypertension. >10,000, fever
death.  Assess for allergic
GI: Nausea, vomiting, reactions
transient increase in  Identify urine
AST, ALT, and serum output, if
LDH and bilirubin; decrease, may
hepatomegaly, indicate
splenomegaly. nephrotoxicity.
 Monitor VS
Hematologic: during treatment,
thrombocytopenic watch for
purpura, anemia. hypotension,
change in pulse
Body as a Whole:  Assess for
Hypersensitivity overgrowth of
(rash, pruritus, infection
urticaria, exfoliative
dermatitis,
eosinophilia, burning
sensation of skin,
drug fever, joint
pains).
 DRUG NAME ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING
RESPONSIBILITY

Salbutamol Causes To relieve Hypersensitivty to  CNS: tremor,  Assess respiratory

bronchodilatation by bronchospasm sympathomimetics, nervousness, function, vital
Drug Class.: action on β2 associated with acute tachydysrythmias, dizziness, capacity, forced
bronchodilator (pulmonary or chronic asthma, severe cardiac insomnia, expiratory
(respiratory smooth receptors) by bronchitis, or other disease. headache, volume, ABGs,
muscle relaxant), increasing levels of reversible obstructive weakness, lung sounds,
beta-agonists cyclic adenosine airway diseases. Also malaise. heart rate,
monophosphate used to prevent  CV: tachycardia, rhythm (baseline
Dosage: 9cAMP), which exercise-induced palpitations, during therapy)
Neb q4 relaxes smooth bronchospasm. hypertension.
muscle; produces  EENT: dry and  Monitor for
bronchodilatation. irritated nose evidence of
and throat with allergic reactions,
inhaled form, paradoxic
nasal congestion, bronchospasm;
epistaxis, withhold doses;
hoarseness. notify prescriber
 GI: heartburn,
nausea,
vomiting,
anorexia, altered
taste, increased
appetite.
 Respiratory:
bronchospasm,
cough, wheezing,
dyspnea,
bronchitis,
increased
sputum.
 DRUG NAME ACTION INDICATION CONTRAINDICATION ADVERSE EFFECTS NURSING
RESPONSIBILITY

Ampicillin Interferes with cell For infections, Hypersensitivity to  CNS: lethargy,  Assess for
wall replication of septicemia penicillins hallucinations, previous
Drug Class.: susceptible anxiety, sensitivity
Broad-spectrum organisms; the cell depressions, reaction to
antibiotic wall, rendered twitching, coma, penicillins or
osmotically unstable, convulsions cephalosporins
Dosage: swells, bursts from  Assess signs and
1 vial 150mg q12, IV osmotic pressure.  GI: Nausea, symptoms of
vomiting, infection:
diarrhea sputum, urine,
stool, WBC
 HEMA: anemia, >10,000, fever
increased  Assess for allergic
bleeding time, reactions
bone marrow  Identify urine
depression, output, if
granulocytopenia decrease, may
indicate
 INTEG: rash, nephrotoxicity.
urticuria  Assess bowel
pattern qd; if
 SYST: severe diarrhea
Anaphylaxis occurs, d/c drugs;
may indicate
pseudomembran
ous colitis
 Assess for
overgrowth of
infection