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    Hypothyrodism

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    kabal321
    This document discusses hypothyroidism. It defines primary hypothyroidism as high serum TSH and low serum free T4. Secondary or central hypothyroidism is characterized by low concentrations of both serum TSH and free T4. The prevalence of hypothyroidism ranges from 0.1-2% while subclinical hypothyroidism has a prevalence of 4-10% in adults, possibly higher in older women. Hypothyroidism is 8-10 times more common in women than men.

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    Hypothyrodism

    Uploaded by

    kabal321
    51 views1 page
    This document discusses hypothyroidism. It defines primary hypothyroidism as high serum TSH and low serum free T4. Secondary or central hypothyroidism is characterized by low concentrations of both serum TSH and free T4. The prevalence of hypothyroidism ranges from 0.1-2% while subclinical hypothyroidism has a prevalence of 4-10% in adults, possibly higher in older women. Hypothyroidism is 8-10 times more common in women than men.

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    This document discusses hypothyroidism. It defines primary hypothyroidism as high serum TSH and low serum free T4. Secondary or central hypothyroidism is characterized by low concentrations of both serum TSH and free T4. The prevalence of hypothyroidism ranges from 0.1-2% while subclinical hypothyroidism has a prevalence of 4-10% in adults, possibly higher in older women. Hypothyroidism is 8-10 times more common in women than men.

    Copyright:

    © All Rights Reserved
    Download as ODT, PDF, TXT or read online from Scribd
    Download as odt, pdf, or txt
    51 views1 page

    Hypothyrodism

    Uploaded by

    kabal321
    This document discusses hypothyroidism. It defines primary hypothyroidism as high serum TSH and low serum free T4. Secondary or central hypothyroidism is characterized by low concentrations of both serum TSH and free T4. The prevalence of hypothyroidism ranges from 0.1-2% while subclinical hypothyroidism has a prevalence of 4-10% in adults, possibly higher in older women. Hypothyroidism is 8-10 times more common in women than men.

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    Tatyana Beaubrun

    February 4, 2017
    Hypothyroidism
    Dr. Mizuno

    As a result of the lack of specificity of clinical symptoms seen in Hypothyroidism, the


    diagnosis is made primarily on laboratory tests. Hypothyroidism is catergorized as either Primary or
    Secondary. Primary Hypothyroidism is defined as high serum TSH and low serum free T4
    concentration. However, subclincal hypothyroidism is characterized by low to normal serum free T4 in
    the presence of high serum TSH. Nonetheless, Central or Secondary Hypothyroidism is characterized
    as low concertrations of both serum TSH and free T4; not appropriately elevated. In terms of
    epidemiology, the prevalence of hypothyroidism ranges from 0.1 2 percent, on the other hand,
    sublinical hypothyroidism has a prevalence 4-10 perent of adults, with possibly a higher frequency in
    older women. Hypothyroidism is 8-10 times more common in women than in men. According to
    study done by the NHANES II, there are significant number of people in the United States have
    laboratory results suggesting thyroid disease, portraying that routine laboratory screen could in fact be
    useful.

    The clinical features of Hypothyroidism vary greatly and depend upon both the severity
    and the duration of the deficiency. However, common signs and symptoms of the diease include,
    fatigue, cold intolerance, weight gain, constipation, dry skin, malagia, and menstrual irregularities.
    Physical exam findings may include, goiter, bradycardia, hypertension, and delayed relaxation phase of
    deep tendon reflexes. Also, a myriad of metabolic abnormalities may also be present, including,
    hypercholesteremia, macrocytic anemia, elevated creatinine kinase, and hyponatremia.

    Primary Hypothyroidism accounts for over 95% of Hypothyroid cases. In most cases, in
    those with signs and symptoms of Hypothyroidism, a serum TSH should be measured. If low, a repeat
    serum TSH should be done along a serum free T4. If TSH remains high, and free T4 is low, then a
    diagnosis of primary hypothyroidism can be made, and therefore T4 should be replaced. If TSH
    remains high, but free T4 is within normal range, this indicates a subclincal hypothyroidism and the
    decsion about replacement therapy is made on a case by case basis, which depends partly on the degree
    of elevation of TSH. If the TSH is normal, but the patient has convincing signs of hypothyroidsm, a
    repeat TSH and free T4 is done to assess for Central Hypothyroidism.

    Secondary, or even Tertiary (Central), Hypothyroidism is characaterized as insufficient


    stimulation of the thyroid gland by TSH

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