Ultrasound Guided Interventional Procedures In.5
Ultrasound Guided Interventional Procedures In.5
Ultrasound Guided Interventional Procedures In.5
DISCUSSION
Anatomy
ip pain can be a manifestation of a broad range of intraarticular or extra-articular pathologies.1,2 Of those, osteoarthritis of the hip and greater trochanteric pain syndrome (GTPS)
are the 2 conditions commonly referred to an anesthesiologist or
pain specialist for injections. Osteoarthritis is the most common
joint disorder in the United States and is the leading cause of
disability in the elderly. Radiographic evidence of osteoarthritis
of the hip is present in about 5% of the population older than
65 years.3,4 However, not all patients with radiographic evidence
of osteoarthritis have symptoms. According to the National Center
for Health Statistics, the Healthcare Cost and Utilization Project
estimated that nearly 368,000 total hip replacements were performed in 2004, costing the nation approximately $5.3 billion.5
Greater trochanteric pain syndrome affects approximately 18%
of the adults in community settings6 and 0.2% of the patient
population in the primary care setting.7 The prevalence increases
in patients with musculoskeletal low-back pain and in women.69
This review focuses only on these 2 causes of hip pain, as
they reect the common reasons for the referral to anesthesiologists. The rst objective of this review was to describe and
summarize the anatomy and sonoanatomy of hip structures relevant to these hip pain conditions. The second objective was to
examine the feasibility, accuracy, and effectiveness of the injections to these structures as well as the injection techniques.
METHODS
A literature search of the MEDLINE database was performed from January 1980 to December 2012 using the search
From the Department of Anesthesia and Pain Management, University
Health Network, University of Toronto, Toronto, Ontario, Canada.
Accepted for publication March 10, 2013.
Address correspondence to: Philip W. H. Peng, MBBS, FRCPC, Founder
(Pain Medicine), Department of Anesthesia and Pain Management,
University Health Network, University of Toronto, 399 Bathurst St,
Toronto, Ontario, Canada M5T 2S8 (e-mail: [email protected]).
Source of funding: Institutional.
The author received equipment support from SonoSite Canada.
Supplemental digital content is available for this article. Direct URL citations
appear in the printed text and are provided in the HTML and PDF
versions of this article on the journals Web site (www.rapm.org).
Copyright 2013 by American Society of Regional Anesthesia and Pain
Medicine
ISSN: 1098-7339
DOI: 10.1097/AAP.0b013e318291c8ed
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FIGURE 1. Front view of hip joint, the labrum (left), and the hip
ligaments. Ischiofemoral ligament cannot be seen from this view
because of the posterior location. Reproduced with permission
from Ultrasound for Regional Anesthesia, www.usra.ca.
lateral, superoposterior, and posterior (Fig. 4 and Video, Supplemental Digital Content 2, http://links.lww.com/AAP/A73,
which shows the 4 facets in the GT in a 3-dimensional view
[reproduced with permission from Ultrasound for Regional Anesthesia, www.usra.ca]).13 The tendons of the gluteus minimus
and anterior and posterior tendons of the gluteus medius insert
into the anterior, lateral, and superoposterior facets, respectively. There is no tendon attached to the posterior facet. Between the posterior facet and gluteus maximus muscle, the
subgluteal maximus bursa (SMaB) can be found.
The muscles in the lateral region are divided into 2 layers.
The origins and the insertions of those muscles are summarized
in Table 1.
The supercial layer, from anterior to posterior, is formed
by the tensor fascia lata and gluteus maximus muscle. The triangular interval between these 2 muscles is lled with fascia lata
overlying the gluteus medius muscle (Fig. 5). This supercial
layer is also called deltoid of the hip joint, reminiscent of
FIGURE 3. Muscles (M) around hip joint. The femoral head and
neck (in dotted line) and the schematic of femoral neurovascular
bundle are shown here for reference. V indicates femoral vein;
A, femoral artery; N, femoral nerve. Reproduced with permission
from Ultrasound for Regional Anesthesia, www.usra.ca.
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Regional Anesthesia and Pain Medicine Volume 38, Number 4, July-August 2013
Peng
FIGURE 4. Figure shows the 4 facets of great trochanter. Reproduced with permission from Ultrasound for Regional Anesthesia,
www.usra.ca.
insertion of the hip joint capsule into the base of the femoral
neck (Fig. 6E; Video 3).
Patient Selection
Intra-articular hip injection is considered for the management of a wide variety of hip disorders, including osteoarthritis,
rheumatoid arthritis, and acetabular labral tears.22,23 Osteoarthritis is the most common joint disorder. Not all patients with
TABLE 1. Origin and Insertion of the Muscles in the Lateral Hip Region
Muscle
Gluteus maximus
Origin
Insertion
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FIGURE 5. Figure shows the muscles and fascia in the lateral hip
region. Reproduced with permission from USRA.
Shoulder
Hip
Supraspinatus
Greater tuberosity
Coracoacromial arch
Subdeltoid, subacromial bursa
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FIGURE 6. Figures show the bursae in the lateral hip region layer by layer. Panel B is a close up of panel A. A indicates supercial
SMaB; B, deep SMaB; C, secondary deep SMaB; D, gluteofemoral bursa; M, muscle. Reproduced with permission from Ultrasound
for Regional Anesthesia, www.usra.ca.
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FIGURE 7. A, Sonoanatomy of the infrainguinal hip region. The position of the transducer is shown in the insert. A indicates femoral
artery; V, femoral vein. B, Sonoanatomy of the anterior hip region when the transducer is placed in the long axis of the femoral
neck. The arrowheads indicate the anterior recess. The position of the transducer is shown in the insert. Reproduced with permission
from Ultrasound for Regional Anesthesia, www.usra.ca.
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TABLE 3. Risk of Injection Following Hip Arthroplasty With Previous Intra-articular Steroid Injection
Authors
Kaspar and de V de Beer41
Sreekumar et al42
McIntosh et al43
Chitre et al44
Sankar et al45
Study Period
Matching
Cohort
THR With
Previous Injection
Location of
Procedure
Infection
19951998
19972004
19982002
19962000
20022009
Yes
Yes
Yes
No
No
40
66
217
36
40
XR
XR
XR
OR
OR
THR indicates total hip arthroplasty; XR, radiological suite; OR, operating room; NS, no signicant difference.
to conrm the location of contrast in the subacromial bursa suggested that x-ray was unreliable in locating a bursa when the
result was validated with cadaver dissection.49 Not surprisingly,
a subsequent multicenter randomized controlled study comparing
the uoroscopy-guided and blind steroid injection for the GTPS
did not show any analgesia advantage of the image-guided technique over the blind technique.50 In contrast, ultrasound is a valuable tool in dening the anatomy and pathology of the gluteal
muscles and tendons in the trochanteric region.46,51,52 At present, literature on the ultrasound-guided injection for GTPS is
FIGURE 9. A, Ultrasonography shows the junction (*) between the anterior and lateral facets of the GT (dotted line). The position of
the transducer is shown in the insert. B, Ultrasonography shows the gluteus medius tendon in short axis. The position of the transducer
shown in the insert is posterior to that shown in A. C, Ultrasonography shows the SMaB. Note that the axis of the transducer is aligned
with the long axis of the IT band as shown in the insert. D, Ultrasonography shows the gluteus minimus tendon. Note that the position
of the transducer is anterior to that shown in A. Reproduced with permission from Ultrasound for Regional Anesthesia, www.usra.ca.
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Regional Anesthesia and Pain Medicine Volume 38, Number 4, July-August 2013
published.9,53 Most of them are case series, and only 3 are randomized trials.50,54,55 In those case series, most of the patients
received only a single injection, and the visual analog pain scale
was not even used as the outcome measure. The case series
showed favorable short-term outcome (3 months) with symptom resolution, and the ability to return to activity ranged from
49% to 100% with steroid injection as the primary treatment
modality.53
One randomized trial examined a uoroscopy guided
against blind injection without any placebo or nontreatment
control.50 By dening success with a positive categorical outcome (50% pain relief and satisfaction with the results), the
outcomes at 3-month assessment were comparable in both
groups (41% vs 47% in x-ray and blind group, respectively).
Complication is rare and minor.
Another large quasi-RCT recruited 229 patients with refractory unilateral GTPS sequentially assigned to 1 of the following groups: a home training program (group A), a single
local corticosteroid injection (group B), or a repetitive lowenergy radial shock wave treatment (group C).54 The response
2013 American Society of Regional Anesthesia and Pain Medicine
was measured on a 6-point Likert scale, and the treatment success was dened as either completely recovered or much improved. Subjects underwent outcome assessments at baseline
and at 1, 4, and 15 months. At 1 month, corticosteroid injection (group B) resulted in the best improvement (success rates
were 7%, 75%, and 13% for groups A, B, and C, respectively).
However, the success rate of the injection group declined with
time and was subsequently superseded by the other 2 groups at
4 and 15 months (success rates were 41%, 51%, and 68% at
4 months and 80%, 48%, and 74% at 15 months for groups A,
B, and C, respectively). Although this study conrmed the shortterm analgesic effectiveness of steroid injection, treating physicians should be aware of the other conservative measures that
could be of benet to those with refractory symptoms from GTPS.
Finally, a recent pragmatic, multicenter, open-label randomized clinical trial evaluated the effect of corticosteroid
injections compared with expectant treatment (usual care, ie,
physiotherapy and analgesic) in patients with GTPS in a primary care setting.55 One hundred twenty patients were randomly allocated to receive either local corticosteroid injections
(n = 60) or usual care (n = 60). All patients were followed
up for 12 months. At the 3-month follow-up, 34% of the patients in the usual care group had recovered (dened as totally
or strongly recovered) compared with 55% in the injection
group (adjusted odds ratio = 2.38; 95% condence interval
[CI], 1.145.00; number needed to treat = 5). Reduction in pain
severity at rest and on activity was greater in the injection
group, with the adjusted difference in pain at rest of 1.18
(95% CI, 0.312.05) and in pain with activity of 1.30 (95%
CI, 0.322.29). The secondary outcomes (Western Ontario and
McMaster Universities Arthritis Index pain and function measures) showed a greater decrease in pain in the injection group
as well. At the 12-month follow-up, differences in outcome
were no longer present. Aside from a short period with supercial pain at the site of the injection, no differences in adverse events were found.
In conclusion, both the case series and randomized trials
supported the safety and short-term analgesic efcacy (3 months)
of steroid injection for GTPS.
CONCLUSIONS
Intra-articular injection of the hip can be reliably performed with ultrasound guidance, targeting the anterior synovial recess. In contrast, the landmark-based technique is
unreliable and subjects the patient to risk of soft-tissue or nerve
injury. The evidence supporting the short-term analgesic efcacy of intra-articular steroid injection is strong. However, controlled trials did not support the use of VS for hip osteoarthritis.
Because current evidence suggests that GTPS is associated
with pathology of gluteus medius and minimus tendons, it is
rational to direct the steroid injection to the tendons involved.
Although the current landmark-based technique is at most modestly accurate, it offers an easy bedside method. Ultrasoundguided technique emerges as a rational technique allowing the
denition of the soft tissue involved. However, more studies
evaluating the feasibility and efcacy are required.
ACKNOWLEDGMENTS
The author would like to thank Lucy Zhang and Bonnie
Tang for their work on the illustrations.
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