U2

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The development of polio vaccines by Jonas Salk and Albert Sabin led to a dramatic reduction in polio outbreaks worldwide. Salk created an inactive vaccine given via injection while Sabin developed a live oral vaccine. Both vaccines have helped nearly eliminate the disease in the United States and many other countries.

The development of polio vaccines by Drs. Jonas Salk and Albert Sabin in the 1950s and 1960s led to a huge decline in polio outbreaks. Salk created the first successful inactivated poliovirus vaccine given via injection in 1954. Then in 1963 Sabin implemented the live oral poliovirus vaccine which was easier to administer.

The Salk vaccine uses an inactivated poliovirus given via injection, while the Sabin vaccine uses a live attenuated virus taken orally. The Sabin vaccine is preferred now because it is easier to administer but it carries a slight risk of infection for those with weak immune systems.

Unit 2 Test Instructor's Edition

Use the following to answer questions 1-6: Read this passage carefully and answer the questions that follow. Polio Vaccinations Poliomyelitis, commonly referred to as polio, may become the second disease, after smallpox, to be eradicated by modern medicine. The disease is intense and debilitating. Its most famous victim was U.S. President Franklin Delano Roosevelt. At one time, people lived in fear of contracting polio, but because of two famous medical researchers and their development of vaccines, outbreaks have declined dramatically. The disease is caused by a virus that enters the body and incubates in the intestines. The virus then enters the bloodstream and attacks the nerves. There are two kinds of polio that can occur. One kind affects the spine and can cause paralysis in the limbs as it did with President Roosevelt. The other kind affects the lungs and makes it difficult, if not impossible, for victims to breathe. Each person with polio will suffer the effects to different degrees. In the early and mid-1900s the disease was widespread. Several unsuccessful attempts at a vaccine were made during this time, but in 1954, testing of a promising vaccine began. The vaccine was developed by Dr. Jonas Salk and utilized inactive strands of the virus. The testing was extremely successful, and soon, the vaccine was being given to children around the world. By 1963, another vaccine procedure was implemented. It was an oral vaccine that was developed by Mr. Albert Sabin. Today, Sabin's vaccine is preferred by some because it is simpler to administer (it is taken orally rather than by injection), but it is slightly more dangerous, especially if recipients have weak immune systems. The vaccine may actually infect those individuals with the disease instead of making them immune to it. With access to these two options for vaccination, instances of the disease today are nearly nonexistent in the United States and have decreased considerably all over the world. In the next few years, it is expected that the disease will be gone altogether. 1. Distribution of the two polio vaccinations has eliminated the disease. A) True B) False 2. Currently there are two choices for polio vaccinations. A) True B) False

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3. President Roosevelt is mentioned in the reading as an example of ___. A) a famous proponent of medical research B) a president of the United States C) the President at the time of the creation of the vaccinations D) a famous sufferer of the disease polio 4. Polio can do all of the following except ___. A) cause paralysis of the limbs B) destroy the intestines C) attack the lungs, making it difficult or impossible to breathe D) attack the spinal cord 5. Sabin's oral vaccine is preferred by some because ___. A) administrators like the low cost B) it is more effective C) it can be administered through syringes D) it is simpler to administer 6. If recipients of the oral vaccination have weak immune systems ___. A) they are at risk of getting polio from the vaccination B) the vaccination will not protect them throughout their lives C) the vaccination will be painful D) the vaccination will definitely infect them with the disease 7. They were asked to ____ their needs and make a list of the items they must have. A) priorities B) prioritize C) priority 8. The visiting nurses found that some things they considered ____ at home, were not important at all in this poor country. A) priorities B) prioritize C) priority 9. The doctors hoped that they could count on the ____ of the board members when they proposed their ideas for the new clinic. A) cooperation B) cooperate C) cooperating

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10. Local nurses, ____ with the visiting doctors, were able to assist in a variety of new procedures. A) cooperation B) cooperate C) cooperating 11. Sophia hoped the psychiatrist would ____ her mother and admit her to the hospital. A) medication B) medicate C) medicated 12. They found that the patient was on an experimental ____ when the symptoms began. A) medication B) medicate C) medicated 13. The virus is known to ___ in the membranes. A) conflict B) occur C) reside D) accompany 14. Once the vaccine became available to children around the globe, outbreaks of the disease ___. A) intensified B) declined C) occurred D) accessed 15. Once ___ to the vaccination was expanded into rural areas, the spread of the disease was contained. A) access B) prioritize C) reside D) implement 16. Cancer research was made (a)n ___ when celebrities began to advertise the need for it. A) conflict B) priority C) occurrence D) residence

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17. With the ___ of the local businesses, advertisements were put up in shop windows and thousands of event tickets were sold. A) cooperation B) conflict C) medication D) practice 18. To stop the outbreak from ___ again, the researchers kept several vials of the antivirus on hand just in case more cases arose. A) intensifying B) accompanying C) occurring D) cooperating 19. In order for the college student to prepare for his studies in the ___ field, he was required to take several chemistry, anatomy, and physiology courses. A) intense B) conflicting C) declining D) medical Use the following to answer questions 20-27: Use the words in the box to complete the sentences. Use each word one time. intense ministry labored cooperate implementation conflict practitioner accompany

20. The internship programs at most hospitals are very ______________: participants work long hours and have a lot of responsibility from the very first day. 21. In the past, most people ______________ on farms or in other outdoor environments to make a living. 22. The rules for child vaccination at the public school ______________ with her religious beliefs, so she decided to teach her children at home. 23. Tiredness and muscle aches are side effects that are known to ______________ this blood-pressure medication.

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24. ______________ of a vaccination program across many countries would require a lot of governmental cooperation. 25. The children were asked to ______________ with the nurses and step forward as their names were called. 26. People blamed the ______________ for the spread of the disease because they did not provide the vaccine quickly. 27. As a medical ______________, Jonathan was dedicated to helping people become, and stay, healthy. 28. What effect do you feel publicity has in aiding research to cure a disease? Can you think of any modern-day examples of a celebrity bringing attention to a certain disease? What effect do you think that attention will have? 29. What medical advancement of the 1900's has had the greatest effect on our society? Give examples to show how this advancement has improved lives.

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Answer Key
1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. B B D B D A B A A C B A C B A B A C D intense labored conflict accompany implementation cooperate ministry practitioner

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