c- Lansoprazole d- Acipimox

i4- Which of the following H2 receptors antagonist has the highest affinity for ? cytochrome p450
a- Nizatidine b- Ranitidine c- Cimetidine d- Famotidine

i5- Which of the following side effects will be caused by antacids containing NAHCO3?i
a- Belching b- Constipation c- Diarrhea d- Blurred vision

i6- Which of the following is a dopamine antagonist?i

a- Granisetron b- Domperidone c- Cisapride d- Loperamide

i7- Which of the following drugs is a systemic amoebicide?i

a- Diloxamide furoate b- Pyrimethamine c- Emetin d- Sodium Stibogluconate

i8- Which of the following drugs is the drug may cause discolouration of nail beds and mucus membranes?i
a- Tetracycline b- Chloroquine c- Doxycycline d- Rifampicin

i9- Which of following drugs is the drug of choice for the treatment of all forms of Schistosomiasis?i
a- Praziquantel b- Mebendazole c- Niclosamide d- Thiabendazole

i10- Which of the following drugs can be used for the treatment of influenza A infection ?i
a- Zidovudine(AZT)i b- Amantadine c- Ribavarin d- Vidarabine

Which of the following drugs is used in the treatment of Leishmaniasis?i -11

a- Pyrimethamine b- Diloxamide

c- Sodium Stibogluconate d- Emetin

i12- Which one of the following statements about tetracycline is not correct?i
a- It is useful for the treatment of resistant strains b- It is contraindicated in pregnancy c- It is safe in infections caused by Chlamydia d- It can lead to discolouration of teeth if given to children

i13- Which of the following drug will antagonize Methotrexate?i

a- Thiamine b- Folic acid c- Biotin d- Cyanocobalamin

i14- lodine is found in all of the following except:i

a- Cod liver oil b- Sea food c- Kelp d- Iodized salt

i15- Match the statements (1- 4) to the trace elements (A-D) listed below.each answer may be used more than once
a- Zinc b- Copper c- Chromium d- Selenium i1. i2. i3. i4. Formation of red and white blood cells Protects cells against damage during cellular m etabolism Promotes wound healing and normal growth Helps maintain normal glucose m etabolism

i16- Match the drug characteristics (1- 4) with the drug listed below (a-d). each answer may be used more than once
a- Auranofin b- Pencillamine c- Aspirin d- Corticosteroids

i1- Platelet function effect i2- Oral form of gold i3- Given on an empty stomach i4- May be given intra articularly

i17- for each side effect (1- 4) list the most likely cause (a-d). each answer may be used more than onces
a- Sodium Bicarbonate b- Aluminium Hydroxide c- Amitriptyline d- Magnesium Hydroxide i1i2i3i4May cause diarrhea Should not be used by patient of heart failure May cause dry mouth Can be incorporated with an antacids mixture to control diarhoea

i18- Pyridoxine requirements may increase during administration of all the following except:i
a- Isoniazid b- Cycloserine c- Oral contraceptives d- Levodopa

i19- All of the following preparations contain alcohol except:i

a- Syrup simplex b- Aromatic ammonia spirit USP c- Terpin hydrate elixir USP d- Belladona tincture B.P

i20- Wich of the following solutions is used as an astringent?i

a- Strong iodine soluotin USP b- Aluminium acetate topical solution USP c- Acetic acid NF d- Benzalkonium chloride solution NF

anextrapyramidal adverse effects is caused by the blocking of:i -21

a- Serotonin receptors in the brain b- Acetylcholine receptors in the brain c- Dopamine receptors in the brain d- Dopamine receptors outside the brain

i22-A rare side effect of some anticonvulsants is Stevens-Johnson syndrome.this is a severe:i

a- Skin reaction b- Bone marrow toxicity c- Renal failure d- CNS suppression

i23-If a women,receiving carbamazepine becomes pregnant,it is important that she receives daily supplements of :i
a- Vit A b- Vit B6 c- Folic acid d- Riboflavin

i 24-Which of the following are side effects of phenytoin treatment?i

a- Acne b- Hirsuitism c- Gingival hyperplasia d- a,b,and c

i25-Which drug is considered as Alpha-1- Adrenergic blocker : i

a- Hydralazine b- Minoxidil c- Prazosin d- Guanethidine

i26-Nitroglycerin-all the following are true except :i

a- Can be dispensed in hospital pack of 500 and 1000 tabs b- Containers must be made of glass and be covered with a tight-fitting ----l c- Close tightly after use

d- Tablets must be stored at controlled R.T e- Tablets not to be refrigerated

i27-The most important adverse reaction to terbutaline is :i

a- Tachycardia b- CNS stimulation c- Fine muscle tremor d- Gastric irritation e- All of the above

i28-Which of the following is true about Penicillin V ?i

a- It is inactivated by gastric acid b- It is acid stable c- It is more active than Benzylpencillin d- It is absorbed better after foods

i29- Which of the following is a quinolone antibiotic ?i

a- Clindamycin b- Chlortetracycline c- Ciprofloxacin d- Clarithromycin

i30-Tuberculosis is caused by a :i
a- Mycoplasma b- Mycobacterium c- Micrococcus d- Microbacter

pertussis is another name for :i-31

a- Cough b- Diphtheria c- Whooping cough d- Scarlet fever

i32-in the treatment of pulmonary tuberculosis,antibiotic treatment must be continued for at least :i
a- 6 months b- 4 months c- 2 months d- 1 month

i33-all of the following are prodrugs except :i

a- Sulindac b- Diazepam c- Enalapril d- Sulfasalazine

i34-which route of drug administration is likely to subject a drug to first pass effect ?i
a- Intravenous b- Inhalation c- Oral d- Sublingual

i35-which of the following statements is/are correct?i

a- Ketamine is used in the treatment of migraine

b- Acute systemic anaphylaxis should be treated immediately by IV injection of adrenaline c- Sulphonylureas are oral anticoagulants d- None of the above

i36-verapamil exerts its effects through which of the following actions?i

a- Preventing entry of calcium channels through slow channels b- Increasing sodium entry c- Antagonizing the opening of the fast sodium channel d- None of the above

i37-cardiac glycoside may be useful in treating all of the following except :i

a- Atrial flutter b- Congestive heart failure c- Ventricular tachycardia d- Atrial fibrillation

i38-streptokinase is indicated for the treatment of :i

a- Impaired fat absorption b- Pulmonary emboli c- Tuberculosis d- Psoriasis

i39-tretinoin is used therapeutically :i

a- As a urinary acidifier b- As an antifungal agent c- In the treatment of tuberculosis d- In the treatment of acne

i40-a calcium channel blocker that is used parenterally for cardiac arrythmias is :i
a- Verapamil hcl b- Nefedipine c- Captopril d- Minoxidil

Wich of the following has not been used for the treatment of -41 Parkinsonism ?i
a- Cogentin b- Artane c- Tofranil d- Kemadrin

i42-The drug that is most likely to induce bronchospasm is :i

a- Pindolol b- Pentoxyfylline c- Omeprazole d- Lisinopril

i43-The anti-inflammatory effect of aspirin is due to :i

a- An anticoagulant effect b- Inhibition of the synthesis of prostaglandins c- An antigen-antibody reaction d- All of the above

i44-The most useful drug in the treatment of diabetes insipidus is :i

a- Glibenclamide b- Insulin c- Metoclopramide d- Desmopressin acetate

i45-The tricyclic antidepressant Iimipramine (Tofranil) has been approved by FDA for use in :i
a- Parkinson's disease b- Hypertension c- Eneuresis d- Peptic ulcer e- None of the above

i46-Regular use of sublingual doses of Nitroglycerin is likely to result in :i

a- Hepatotoxicity b- Nephrotoxicity c- Peptic ulcer d- Tolerance

i47-All of the following are beta blockers except :i

a- Metoprolol (Lopressor)i b- Nadolol (Corgard)i c- Enalapril (Renitec)i d- Propranolol (Inderal)i

i48-Bisacodyl frequently can cause :i

a- Abdominal cramps b- Constipation c- Skin rashes d- Dizziness

i49-An example of a pure opioid antagonist :i

a- Naloxone hcl (Narcan)i b- Pentazocine (Sosegon)i c- Nalbuphine(Nubain)i d- Morphine

i50-Carbamazepine (tegretol) is used for treatment of :i

a- Eneuresis b- Trigeminal neuralgia c- Attention of defict disorder d- Psoriasis

Buspirone (Buspar) is classified pharmacologically as :i-51

a- Antidepressant b- Anxiolytic agent

c- Narcotic analgesic d- Hypnotic

i52-Dilitiazem is used primarily for its ability to produce :i

a- Cough depreaaion b- Analgesia c- Calcium channel blockade d- Emesis

i53-Carbocysteine is an agent used clinically as :i

a- Laxative b- Cough suppressant c- Diagnostic agent d- Mucolytic

i54-The following drugs may be given by sublingual route except :i

a- Digoxin b- Nifedipine c- Nitroglycerin d- Isoprenaline

i55-Match the following antibiotics to the best description given below (a-d)i
a- Betalactam antibiotic active against pseudomonas b- Pencillinase resistant betalactam c- Contraindicated in children d- Inhibits renal metabolism i1- Piperacillin i2- Tetracycline i3- Flucloxacillin i4- Cilastin

i56-Disinfectants are expected to destroy or inhibit the growth of microbes which are in :i
a- The vegetative stage b- The sporing stage c- Both a and b d- None of the above

i57-Which of the following is not a storage area for iron:i

a- Reticuloendothelial system b- Kidney c- Hepatocytes d- Muscle

i58-Which of the following is a sulphonylurea antidiabetic drugs?i

a- Chlorpropamide b- Bum etanide c- Acetazolamide d- Frusemide

i59-One drop has a volume of :i

a- 0.5 ml

b- 0.1 ml c- 0.15 ml d- Variable, depending on the liquid and the dropper

: i60-Ketorolac is used in eye preparations as a/an

a- Anti-inflammatory b- Antihistamine c- Astringent d- Corticosteroid

i61-Which of the following drugs is a vasodilator?i

a- Methyldopa b- Mexitilline c- Prazocin d- Propranolol

i62-Which of the following drugs is not associated with haemolytic aneamia?i

a- Mefenamic acid b- Methyldopa c- Methadone d- Methyl testosterone

i63-Which of the following Vitamins is essential in the formation of Prothrombin?i

a- Vitamin A b- Vitamin B complex c- Vitamin E d- Vitamin K

i64-Which of the following is not used as an antitussive ?i

a- Noscapine b- Pethidine c- Codeine d- Diphenhydramine

i65-Which of the following Local Anaesthetics is useful for topical administration only?i
a- Lidocaine b- Bupivacaine c- Benzocaine d- Procaine

i66-The iron preparation given by the intravenous route is:i

a- Ferrous sulphate b- Iron-dextran c- Ferrous gluconate d- Iron-sorbitol citric acid

i67-Carotenoids are precursors for which vitamin?i

a- Vitamine E b- Vitamine D c- Vitamine A d- Vitamine K

i68-Which of the following is recommended for dyspepsia in pregnancy? i

a- Gaviscon b- Pylorid c- De-nol d- Zantac

i69-Which of the following drug interactions is not used therapeutically? i

a- Epinephrine / Lidocaine b- Probenicid / Penicillin c- Pseudoephedrine / Salbutamol d- Trimethoprim / Sulphamethoxazole

i70-The maximum daily dose of Glibenclamide is

a- 2.5 mg/day b- 5 mg/day c- 20 mg/day d- 30 mg/day

i71-Which of the following is not used to treat psychosis?i

a- Aluoxetine b- Haloperidol c- Perphenazine d- Resperidone

i72-A sympathomimetic often present in OTC appetite suppressant is:i

a- Ephedrine b- Phenylephedrine c- Phenylpropanolamine (PPA)i d- Caffeine

i73-Opioids have the following uses except:i

a- Anti tussive b- Anti-inflammatory c- Analgesics d- Pre anaestetics

i74-Levocabastine is a/an:i
a- Antihistamine b- Anti microbial c- Anti inflammatory d- Corticosteroid

i75-Which of the following is not used as aprophylaxis for migraine?i

a- Pizotifin b- Metoprolol c- Prazocin d- Propranolol

i76-The most common side effect of sublingual glyceryl trinitrate is:i

a- Nausea b- Throbbing headache c- Hypertension d- Skin rash

i77-All of the following are common iodine deficiency symptoms except:i

a- Goitre b- Intellectual disability c- Growth retardation d- Decreased early and late pregnancy miscarriage

i78-Which of the following insulins has the shortest duration of action?i

a- Isophane insulin b- Soluble insulin c- Insulin zinc suspension d- Protamine zinc insulin

i79-Vasopressin (ADH) is used therapeutically for:i

a- Treatment of polyuria caused by hypercalceamia b- Treatment of pituitary diabetes insipidus c- Decrease chest pain in refractory unstable angina d- Increasing uterine contractivity

i80-oral sympathomimetic decongestants should be avoided in patients who have:i

a- Asthma b- Cough c- Hypertension d- Throat infections

Percentage of total body iodine in thyroid glands is :i-81

a- 50% b- 75% c- 90% d- 95%

i82-Daily saliva secretion is :i

a- 1 litres b- 1.5 litres c- 1.8 litres d- 2 litres

i83-Normal serum bilirubin is :i

a- 0.5 - 1 mg %i b- 1 - 3 mg %i c- 3 - 4 mg %i d- 4 - 5.5 mg %i

i84-Ovary secretes :i
a- FSH and LH only b- Oestrogen and Progestrogen only c- Oestrogen, Progestrogen and Androgen d- All of these

i85- The absence of anti-A and anti-RH agglutinin plasma means that the subject is :i
a- A+ve or AB+ve b- A-ve or AB-ve c- B+ve or AB+ve d- Type O

i86-The most important buffer in extracellular fluids is:i

a- Acetate b- Bicarbonate c- Phosphate d- Protein

i87- Reticulocytosis indicate :i

a- Increased RBC formation b- Decreased WBC formation c- Decreased RBC formation d- Increased WBC formation

i88-Ketosteroids in urine include :i

a- Adrenal and testicular function b- Pituitary function c- Hypothalamic function d- Pancreatic function

i89-Which blood can be safely given to a patient of blood group AB positive?i

a- AB negative b- A positive c- B positive d- O positive

i90- Function of gall bladder is :i

a- Increase alkalinity of bile b- Increase concentration of bile c- Increase intrabiliary presence d- Increase phosphate level

Insulin causes :i-91

a- Increase glucose m etabolism b- Increase gluconeogenesis c- Increase lipolysis d- Increase glycogenolysis

i92- Major pathway of excretion of Calcium is :i

a- Kidney b- Gut c- Kidney and Gut d- None of the above

i93- The secretion of aldosterone is controlled by :i

a- Angiotensin b- ACTH c- Epinephrine d- Insulin

i94- First relay station of pain is :i

a- spinal cord b- Medulla c-pons d- thalamus

i95- Testosterone is secreted by :i

a- sertoli cells b- leydig cells c- germ cells d- adrenal medulla

i96- Which neurotransmitter controls secretion of prolactin?i

a- Dopamine b- Serotonin c- Somatostatin d- GABA

i97- Nucleus of a atom contains :i

a- Electrons b- Only Protons c- Electrons and Protons d- Protons and Neutrons

i98- Which of the following is the fastest to be absorbed from the stomach?i
a- Carbonhydrate b- Proteins c- Fats d- Water

i99- Function of calcitonin is to :i

a- Decrease level of Calcium b- Increase level of Calcium c- Increase level of Mg d- Increase level of Potassium

i100- The following are true of insulin except :i

a- Glycopeptide b- Secreted by beta cells c- Causes lipogenesis d- Promotes glycogenesis

i1-----------------------D i2-----------------------D i3-----------------------D i4-----------------------C i5-----------------------A i6-----------------------B i7-----------------------A i8-----------------------D i9-----------------------A i10----------------------B ----------------------------------------------------------------

i11----------------------C i12----------------------A i13----------------------B i14----------------------A i15 i1------------------B i2------------------D i3------------------A i4------------------C i16 i1------------------C i2------------------A i3------------------B i4------------------D i17 i1------------------D i2------------------A i3------------------C i4------------------B i18-----------------D i19-----------------A i20-----------------B ----------------------------------------------------------------

i21-----------------------C i22-----------------------A i23-----------------------C i24-----------------------D i25-----------------------C i26-----------------------A i27-----------------------E i28-----------------------B i29-----------------------C i30-----------------------B ----------------------------------------------------------------

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i41-----------------------C i42-----------------------A i43-----------------------B i44-----------------------D i45-----------------------C i46-----------------------D i47-----------------------C i48-----------------------A i49-----------------------A i50-----------------------B ----------------------------------------------------------------

i51-----------------------B i52-----------------------C i53-----------------------D i54-----------------------A i55 i1------------------A i2------------------C i3------------------B i4------------------D i5------------------C i56-----------------------A i57-----------------------B i58-----------------------A

i59-----------------------D i60-----------------------A ----------------------------------------------------------------

i61-----------------------C i62-----------------------D i63-----------------------D i64-----------------------B i65-----------------------C i66-----------------------B i67-----------------------C i68-----------------------A i69-----------------------C i70-----------------------C ----------------------------------------------------------------

i71-----------------------A i72-----------------------C i73-----------------------B i74-----------------------A i75-----------------------B i76-----------------------B i77-----------------------D i78-----------------------B i79-----------------------B i80-----------------------C ----------------------------------------------------------------

i81-----------------------C i82-----------------------D i83-----------------------A i84-----------------------C i85-----------------------A i86-----------------------B i87-----------------------A

i88-----------------------A i89-----------------------A i90-----------------------B ----------------------------------------------------------------

i91-----------------------A i92-----------------------B i93-----------------------A i94-----------------------A i95-----------------------B i96-----------------------A i97-----------------------D i98-----------------------D i99-----------------------A i100----------------------A