1 Cinchona
1 Cinchona
1 Cinchona
Source
• Known as
ledger bark
• From various
species of
Cinchona
• C.officinalis
• C.succirubra
• C.ledgeriana
• C.calisaya
• Rubiaceae
family
Cultivation
• Requires acidic soil
• Seeds sorted & sown in boxes
• Germinate in 3 wks
• When 5cm ht planted in nurseries
covered by rough roofs & shade
gradually removed as they grow
• When 20 – 30 cm ht planted in clearing
• Planted in cloudy weather during rainy
season 1mt apart
• When 4 yrs old plants thinned out to
the extent of 25% & again next year
• Finally only 50% of plants remain
• Collected when 6yrs old
• Coppicing method used
• In Java uprooting method used when
plants are 12yrs old
Collection
• Alkaloids
• Present in combination with
quinic acid & cinchotannic acid
3. Quinine
4. Quinidine
5. Cinchonine
6. Cinchonidine
7. Quinovin glycoside
Uses
• Bitter stomachic
• Source of quinine
• Astringent
• Antimalarial
• Used in Cardiac arrythmias &
atrial fibrillation