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    Pathophysiology Biliary Atresia

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    PATHOSHOPPE
    Biliary atresia is a condition caused by an unknown etiology that results in immune-mediated injury and fibrosis of the bile ducts in neonates. This blocks the flow of bile from the liver to the intestine, leading to jaundice, gray stool, and accumulation of bilirubin in the blood and urine. Without treatment, it can cause progressive liver damage and liver failure.

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    Pathophysiology Biliary Atresia

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    PATHOSHOPPE
    1K views1 page
    Biliary atresia is a condition caused by an unknown etiology that results in immune-mediated injury and fibrosis of the bile ducts in neonates. This blocks the flow of bile from the liver to the intestine, leading to jaundice, gray stool, and accumulation of bilirubin in the blood and urine. Without treatment, it can cause progressive liver damage and liver failure.

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    Pathophysiology Biliary Atresia

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    Biliary atresia is a condition caused by an unknown etiology that results in immune-mediated injury and fibrosis of the bile ducts in neonates. This blocks the flow of bile from the liver to the intestine, leading to jaundice, gray stool, and accumulation of bilirubin in the blood and urine. Without treatment, it can cause progressive liver damage and liver failure.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    1K views1 page

    Pathophysiology Biliary Atresia

    Uploaded by

    PATHOSHOPPE
    Biliary atresia is a condition caused by an unknown etiology that results in immune-mediated injury and fibrosis of the bile ducts in neonates. This blocks the flow of bile from the liver to the intestine, leading to jaundice, gray stool, and accumulation of bilirubin in the blood and urine. Without treatment, it can cause progressive liver damage and liver failure.

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    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 1

    PATHOPHYSIOLOGY

    BILIARY ATRESIA

    PREDISPOSING FACTORS PRECIPITATING FACTORS


     Race: Asian  maternal nutrition
     Sex: female Etiology: Unknown  maternal exposure to
     Age: neonate teratogens
     Immaturity of immune
    system
    Viral exposure Immaturity of neonatal immune
    system

    Immune-mediated bile duct injury

    Intrahepatic and extrahepatic bile duct


    fibrosis

    Ductal obstruction

    Blocks bile(conjugated bilirubin) flow Lack of bilirubin and metabolites in Gray-colored stool
    to the intestine intestine

    Bile excessively accumulate in blood

    Icteric sclera Excess amount deposits Excess amount excretes through


    to skin urine

    hyperbilirubinemia

    Yellowish skin Tea-colored urine


    (Jaundice)

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