Ciprobay is an antibiotic in the quinolone class used to treat various bacterial infections. It works by inhibiting DNA gyrase in bacteria. It comes as tablets from 125-750mg and intravenous infusions from 100-400mg. Common side effects include central nervous system issues, gastrointestinal problems, and tendon damage. It should be used with caution in patients with epilepsy or central nervous system disorders due to risk of seizures.
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Ciprobay is an antibiotic in the quinolone class used to treat various bacterial infections. It works by inhibiting DNA gyrase in bacteria. It comes as tablets from 125-750mg and intravenous infusions from 100-400mg. Common side effects include central nervous system issues, gastrointestinal problems, and tendon damage. It should be used with caution in patients with epilepsy or central nervous system disorders due to risk of seizures.
Ciprobay is an antibiotic in the quinolone class used to treat various bacterial infections. It works by inhibiting DNA gyrase in bacteria. It comes as tablets from 125-750mg and intravenous infusions from 100-400mg. Common side effects include central nervous system issues, gastrointestinal problems, and tendon damage. It should be used with caution in patients with epilepsy or central nervous system disorders due to risk of seizures.
Copyright:
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Download as DOC, PDF, TXT or read online from Scribd
Ciprobay is an antibiotic in the quinolone class used to treat various bacterial infections. It works by inhibiting DNA gyrase in bacteria. It comes as tablets from 125-750mg and intravenous infusions from 100-400mg. Common side effects include central nervous system issues, gastrointestinal problems, and tendon damage. It should be used with caution in patients with epilepsy or central nervous system disorders due to risk of seizures.
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Brand name: Ciprobay
Generic name: Ciprofloxacin
Drug Classification: Antibiotics (Quinolones) Indications: Infections of the respiratory tract, middle ear, sinuses, eyes, kidneys and urinary tract, genital organs, abdomen, skin and soft tissues, bones and joints; further, septicemia, infections in patients with reduced host defense and for selective intestinal decontamination in immuno suppressed patients. Mechanism of action: Inhibits DNA-gyrase in susceptible organism; inhibits relaxation of supercoiled DNA and promotes breakage of double-stranded DNA. Dose: Tab 125-750 mg orally bid. Respiratory tract infections 500 mg bid. Acute gonorrhea 250 mg orally as single dose. The normal dose must be reduced if creatinine clearance is < 20 ml/min. 500 XR tab acute uncomplicated UTI (acute cystitis) 1 tab/day for 3 days IV infusion 100-200 mg bid. Resp tract infections 200-400 mg bid. Acute, uncomplicated UTI and extra genital gonorrhea 100 mg bid. Pre-menopausal cystitis and acute, uncomplicated gonorrhea single dose 100 mg. Complicated cystitis and diarrhea 200 mg bid. Severe infections 400 mg tid. Contraindication: hypersensitivity to ciprofloxacin or other quinolones. Children, adolescents, pregnancy and lactation. Special Precautions: Epilepsy, CNS damage. Photosensitivity. May affect ability to drive or operate machinery. Adverse Reactions: CNS: seizures, dizziness, drowsiness, headache, insomnia, acute psychosis, agitation, confusion, hallucination, increased intracranial pressure, light-headedness, tremors CV: arrythmias, QT prolongation, vasodilation GI: hepatotoxicity, pseudomembranous colitis, abdominal pain, diarrhea, nausea, altered taste. GU: interstitial cystitis, vaginitis. Derm: photosensitivity, phototoxicity Endo: hyperglycemia, hypoglycemia. Local: phlebitis at IV site MS: tendonitis, tendon rupture Misc: hypersensitivity reactions including anaphylaxis, Stevens - Johnson syndrome, lymphadenopathy. Form: Tablet (Film- coated) - 250mg, 500mg, 750mg; IV infusion- 100mg/ 50mL, 200mg/ 100mL, 400mg/ 200mL Pregnancy Risk Category: C Nursing Responsibilities: Assess patient for infection prior to and during therapy. Obtain specimens for culture and sensitivity before initiating therapy Observe patient for signs and symptoms of anaphylaxis (rash, pruritus, laryngeal edema, wheezing) Monitor prothrombin time closely in patients receiving fluoroquinolones and warafarin