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    Ribosome (Brief Summary)

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    api-19916399
    Ribosomes are organelles found in the cytoplasm and attached to the endoplasmic reticulum that synthesize proteins. They contain two subunits - a large 60S subunit and a small 40S subunit. The subunits contain ribosomal RNA and proteins. Ribosomes use mRNA as a template to link amino acids specified by the genetic code into a polypeptide chain. There are four binding sites on the ribosome that facilitate the movement and bonding of amino acids during protein synthesis.

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    Ribosome (Brief Summary)

    Uploaded by

    api-19916399
    32 views6 pages
    Ribosomes are organelles found in the cytoplasm and attached to the endoplasmic reticulum that synthesize proteins. They contain two subunits - a large 60S subunit and a small 40S subunit. The subunits contain ribosomal RNA and proteins. Ribosomes use mRNA as a template to link amino acids specified by the genetic code into a polypeptide chain. There are four binding sites on the ribosome that facilitate the movement and bonding of amino acids during protein synthesis.

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    ribosome(brief summary)

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    Ribosomes are organelles found in the cytoplasm and attached to the endoplasmic reticulum that synthesize proteins. They contain two subunits - a large 60S subunit and a small 40S subunit. The subunits contain ribosomal RNA and proteins. Ribosomes use mRNA as a template to link amino acids specified by the genetic code into a polypeptide chain. There are four binding sites on the ribosome that facilitate the movement and bonding of amino acids during protein synthesis.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    32 views6 pages

    Ribosome (Brief Summary)

    Uploaded by

    api-19916399
    Ribosomes are organelles found in the cytoplasm and attached to the endoplasmic reticulum that synthesize proteins. They contain two subunits - a large 60S subunit and a small 40S subunit. The subunits contain ribosomal RNA and proteins. Ribosomes use mRNA as a template to link amino acids specified by the genetic code into a polypeptide chain. There are four binding sites on the ribosome that facilitate the movement and bonding of amino acids during protein synthesis.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
    Download as ppt, pdf, or txt
    of 6

    Ribosome

    A brief summary
    Classification
    • According to The relation with ER:

    • Free ribosome ： dissociate in the


    cytoplasm
    • Fixed ribosome: ： bind to
    endoplasmic reticulum
    Four positive site of ribosome
    The place for 2 amino Provide the energy for the
    acid form a bond aminoacyl-tRNA movement
    from A site to P site

    G site
    T factor

    A
    P 3
    ，
    ， site
    5 site

    mRNA
    The organization of ribosome

    28S
    RNA

    5.8S
    RNA +~45 kinds protein

    60S 5S
    RNA

    80S 18S RNA + ~33 kinds protein


    40S
    Genetic code
    • Start codon (AUG)
    • Stop codon ( UGA, UAA, UAG)
    • Degenerate: Since there are only 20 amino
    acids and 64 possible codons , most amino
    acids are specified by more than one codon;
    hence the code is said to be degenerate.
    Signal theory for
    the translocation of protein
    mRNA
    1.Translation complex formed
    ribosome

    signal sequence SRP (signal recognition particle)


    of emerging protein
    2. Recognition between SRP
    and signal sequence

    translocon SRP
    receptor
    3.The recognition 5.Proteins
    4.Protein channel
    between SRP and SRP-R fall into
    formed
    ER

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