Zoo143 Clinical Parasitology Topic: Parasites of Clinical Significance

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Zoo143 Clinical Parasitology Topic: Parasites of Clinical Significance

Bongco, Natalie Gail T. Feb. 2,2013 Prof: Dr. Veloso

Giardia lamblia

Organism: Giardia lamblia


Scientific name: Giardia intestinalis, Lamblia intestinalis, Giardia duodenale

Common name: Beaver fever

Giardia lamblia
It is a flagellated protozoan parasite that colonizes and reproduces in the small intestine
The parasite attaches to the epithelium by a ventral adhesive disc and reproduces via binary fission. It does not spread through the bloodstream or other parts of the G.I. tract but remains confined to the lumen of the small intestine. Its trophozoites absorb their nutrients from the lumen of the small intestine, and are anaerobes.

Lifecycle

Host

Mode of transmission: Pathology


Faecal-oral route
Occur in city reservoirs and persist after water treatment since cysts are chlorine-resistant.

Zoonitic transmission: can be transmitted by means of swimming in contaminated streams or lakes or camping in the wilderness.

Signs and Symptoms


Diarrhea Abdominal pain, particularly cramping Common manifestation include bloating, nausea with or without vomiting, malaise, and fatigue.

Complications
Malabsorption syndrome
Cramping diarrhea Weight loss

Diagnosis
Antigen testing
Stool microscopy String test

Management
Preventive

Therapeutic

Pharmacologic
Metronidazole
Tinidazole Nitrazoxanide

References
http://www.medicinenet.com/giardia_lamblia/page2.ht m
http://www.medicinenet.com/giardia_lamblia/page3.ht m http://microbewiki.kenyon.edu/index.php/Giardia_lamb lia

http://en.wikipedia.org/wiki/Giardia_lamblia

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