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Background: The skin score, a subjective assessment of skin elasticity, is widely used in patients with systemic sclerosis. Although this scoring method is regarded as a validated and accepted tool, the interobserver and intraobserver... more
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      DermatologyLinear modelsElasticitySystemic sclerosis
Tympanosclerosis is a sequel of chronic otitis media characterized by the deposition of calcareous plaques following hyaline degeneration in the fibrous layer of the tympanic membrane and inside middle ear mucosa. It usually results from... more
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      SurgeryAdolescentChildChronic Disease
OBJECTIVE Meyer's loop, the most vulnerable part of the optic radiations during approaches to the temporomedial region, extends to the tip of the temporal horn and is often encountered in epilepsy surgery. The risk of damaging... more
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      SurgeryNeurosurgeryRadiationEpilepsy
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      Portal hypertensionYoung AdultClinical SciencesIntestinal Obstruction
Schnitzler's syndrome is a rare combination of chronic urticaria, fever of unknown origin, disabling bone pain, and monoclonal gammopathy. We report a case with an unusual radiological manifestation as a solitary sclerotic lesion of the... more
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      Computed TomographyPainMagnetic Resonance ImagingTreatment Outcome
To critically assess the value of material-specific memory deficits in lateralizing temporal lobe dysfunction preoperatively, we compared the neuropsychological data of 50 consecutive patients with unilateral mesial temporal lobe epilepsy... more
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      ElectroencephalographyAdolescentHippocampusTemporal Lobe Epilepsy
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      PsychologyMagnetic Resonance ImagingMRIElectroencephalography
clerosing adenosis is a benign proliferative disease of the breast that may present a broad spectrum of imaging findings, from minimal lobular changes to macroscopic mass lesions. The main histopathological alterations of the terminal... more
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      BreastMammographyRetrospective StudiesDiagnostic and Interventional Radiology
Theories of rhetoric and architecture suggest that buildings designed to be high ranking according to the Western architectural decorum have more impact on the minds of their beholders than low-ranking buildings. Here, we used... more
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      ArchitectureVisual perceptionElectroencephalographyAdolescent
Bone islands are usually considered benign, stable, nonprogressive lesions, radiographically characterized by an ovoid, round, or oblong homogeneously dense and sclerotic focus in the spongiosa, with a preference for the long bones and... more
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      ChildFemurOrthopedicsHamartoma
Fibrosing mediastinitis due to Aspergillus with dominant cardiac involvement: report of two autopsy cases with review of literature
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      MyocarditisAspergillus flavusAutopsyCardiovascular Pathology
Calcific aortic valve disease (CAVD) is the most common acquired valvular disorder in developed countries. CAVD ranges from mild thickening of the valve, known as aortic valve sclerosis (AVSc), to severe impairment of the valve motion,... more
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      MedicineCalcinosisPrognosisBiological markers
Mesial ternDora1 sclerosis and A. 0. investigations Cook MJ. Mesial temporal sclerosis and volumetric investigations. Acta Neurol Scand 1994: Suppl. 152: 109-1 14. Volumetric MRI data acquisition permits reliable and accurate measurement... more
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      Magnetic Resonance ImagingHippocampusBrainTemporal Lobe Epilepsy
This article summarizes the current hypotheses that link visceral obesity and kidney malfunction and provides information on the epidemiology and renal pathology resulting from visceral obesity.
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      Nutrition and DieteticsObesityKidney diseasesMalnutrition
The term hippocampal sclerosis was originally used to describe a shrunken and hardened hippocampus, which histologically displayed neuronal loss and glial proliferation. These alterations are mainly located in the hilus of the dentate... more
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      Magnetic Resonance ImagingHippocampusTemporal LobeTemporal Lobe Epilepsy
A diaphyseal, intramedullary, highly sclerotic lesion presenting as a pathological fracture, without a periosteal reaction or an appreciable soft tissue component on radiographs was investigated. A discrepancy between the MRI and... more
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      AdolescentMedicineOsteosarcomaDifferential Diagnosis
Cranio-cerebral erosion is a well-known complication of calvarian fracture with underlying dural tear and cerebral injury in infancy and early childhood. The anatomy, pathogenesis and natural evolution of these lesions remain obscure. The... more
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      AdolescentEarly ChildhoodInfantParietal Bone
The severity index is a new echocardiographic measure that is thought to be an accurate indicator of aortic leaflet pathology in patients with AS. However, it has not been validated against cardiac catheterization or Doppler... more
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      CardiovascularClinical SciencesCardiac CatheterizationSpectrum
improved in 95.6% of the SAH patients and 89.8% of the STL patients. These differences were not statistically significant. Left-sided TLE patients had a significantly worse verbal memory outcome irrespective of the surgical method.... more
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      EpilepsyTreatment OutcomeHippocampusTemporal Lobe
Some variants of the brain derived neurotrophic factors (BDNF) gene, namely the Val66Met (rs6265), may contribute the risk for epilepsy development. We aimed to investigate if this polymorphism was associated with the risk for epilepsy... more
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      PsychologyBrazilComorbiditySeizure
Our aim is to assess the subfield-specific histopathological correlates of hippocampal volume and intensity changes (T1, T2) as well as diffusion MRI markers in TLE, and investigate the efficacy of quantitative MRI measures in predicting... more
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      Cognitive ScienceMagnetic Resonance ImagingDiffusion Tensor ImagingLinear models
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      Nonparametric StatisticsEpilepsySemantic MemoryEpisodic Memory
Recent observations suggest that neurocysticercosis (NCC) might act as an initial precipitating injury (IPI) causing mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE-HS). A total of 191 patients from Brazil, a... more
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      PsychologyMagnetic Resonance ImagingEpilepsyBrazil
Magnetic resonance imaging-positive temporal lobe atrophy with temporo-polar grey/white matter abnormalities (usually called 'blurring') has been frequently reported in patients with temporal lobe epilepsy associated with hippocampal... more
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      Magnetic Resonance ImagingMedicineHippocampusTemporal Lobe
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      PsychologyDepressionMedicineSeizure
Viral infection of the CNS can result in encephalitis and acute seizures, increasing the risk for later-life epilepsy. We have previously characterized a novel animal model of temporal lobe epilepsy that recapitulates key sequela in the... more
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      PsychologyAnxiety DisordersNeurobiology Of DiseaseAnimal Behavior
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      Magnetic Resonance ImagingAdolescentMedicineEndoscopy
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      Magnetic Resonance ImagingAgingElectroencephalographyMedicine
The Southern blot hybridization technique has been applied to study the configuration of immunoglobulin and T-cell receptor genes in 6 cases of the so called mediastinal large cell lymphoma with sclerosis. This lymphoma has been recently... more
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      ImmunohistochemistryT cell receptorLymphomaNucleic acid hybridization
Objectives To investigate whether bone erosions in patients with rheumatoid arthritis (RA) show evidence of repair. Methods 127 erosions were identifi ed in metacarpophalangeal joints 2-4 of the right hands of 30 RA patients treated with... more
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      ImmunologyRheumatoid ArthritisFollow-up studiesBone marrow
California sea lions (Zalophus californianus) are abundant human-sized carnivores with large gyrencephalic brains. They develop epilepsy after experiencing status epilepticus when naturally exposed to domoic acid. We tested whether sea... more
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      EpilepsySomatostatinHippocampusChronic Disease
Objectives-To examine the degree of hippocampal atrophy in patients with temporal lobe epilepsy and proved hippocampal sclerosis to determine whether or not patients with febrile seizures have more severe hippocampal atrophy. To determine... more
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      NeurologyMagnetic Resonance ImagingHippocampusTemporal Lobe Epilepsy
We aimed to identify the brain areas involved in verbal and visual memory processing in normal controls and patients with unilateral mesial temporal lobe epilepsy (MTLE) associated with unilateral hippocampal sclerosis (HS) by means of... more
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      Cognitive ScienceMagnetic Resonance ImagingBrain MappingHippocampus
Intracranial depth electrode EEG records of 478 seizures, recorded in 68 patients undergoing diagnostic monitoring with depth electrodes, were evaluated to investigate the correlates of electrographic onset patterns in patients with... more
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      Magnetic Resonance ImagingElectroencephalographyAdolescentHippocampus
Liposclerosing myxofibrous tumor is a benign fibro-osseous lesion, with distinct radiographic and clinical features and diverse histologic patterns. This lesion occurs in the fourth decade of life, with equal male and female incidence.... more
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      Incidental FindingsDifferential DiagnosisIncidenceClinical Sciences
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      PathologyMagnetic Resonance ImagingElectroencephalographyHippocampus
Sclerosing peritonitis (SP) after liver transplantation has been described in 10 cases in the literature. The etiology is still unknown; however, SP is considered a consequence of chronic irritation and inflammation. It can be classified... more
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      Case ReportLiver CirrhosisLiver TransplantationFibrosis
To evaluate whether proposed diagnostic criteria applied to magnetic resonance (MR) images of patients with laryngeal and hypopharyngeal carcinoma may be used to distinguish neoplastic from inflammatory involvement of the laryngeal... more
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      RadiologyBiomedical EngineeringMagnetic Resonance ImagingProspective studies
Background: Where neurocysticercosis (NCC) is endemic, chronic calcified neurocysticercosis (cNCC) can be observed in patients with mesial temporal lobe epilepsy associated with hippocampal sclerosis (MTLE-HS). Considering that both... more
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      EngineeringPhysicsChemistryDecision Making
Patients with intractable temporal lobe epilepsy and mesial temporal sclerosis often have histories of severe febrile convulsions as infants. Diagnostic advances made possible by magnetic resonance imaging have shown that very prolonged... more
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      Cognitive ScienceCausalityMedicineHippocampus
Epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis. Seizures in mesial temporal lobe epilepsy with hippocampal sclerosis are typically drug-resistant, and mesial... more
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      PsychologyMedicineHippocampusTemporal Lobe
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      NephrologyAdolescentClinical SciencesPeritoneal Dialysis
Objective: To perform a multicenter review of the clinical features and treatment of 31 patients with idiopathic sclerosing orbital inflammation. Methods: We included all patients with histologically confirmed idiopathic sclerosing... more
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      Early InterventionMagnetic Resonance ImagingArchivesAdolescent
We studied a group of 31 temporal lobe epilepsy patients (25 left, 6 right) with unilateral hippocampal sclerosis evident on magnetic resonance imaging. Single slice T2 relaxation times were acquired for the left and right hippocampi.... more
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      PsychologyMagnetic Resonance ImagingImagingAdolescent
In this study, we investigate the hypothesis that IgG4-related autoimmune reaction is involved in the formation of inflammatory aortic aneurysms (IAA). We obtained 23 cases of IAA and 11 cases of atherosclerotic aortic aneurysms (AAA) as... more
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      BiologyMedicineAutoimmune diseasesAged
Immunoglobulin G4-related systemic disease (IgG4-RSD) is a recently defined emerging entity characterized by a diffuse or mass forming inflammatory reaction rich in IgG4-positive plasma cells associated with fibrosclerosis and... more
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      MedicineAutoimmune diseasesChronic PancreatitisLymphatic Diseases
BACKGROUND People with epilepsy (PWE) in low- and middle-income countries may not access the health resources that are considered optimal for epilepsy diagnosis. The diagnostic yield of magnetic resonance imaging (MRI) has not been well... more
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      Magnetic Resonance ImagingEpilepsyDeveloping CountriesAdolescent
PURPOSE To assess the clinical significance of temporal pole abnormalities (temporopolar blurring, TB, and temporopolar atrophy, TA) in patients with temporal lobe epilepsy (TLE) and hippocampal sclerosis (HS) with a long post-surgical... more
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      PsychologyMagnetic Resonance ImagingTreatment OutcomeAdolescent
Temporal lobe epilepsy (TLE) is frequently associated with hippocampal sclerosis, possibly caused by a primary brain injury that occurred a long time before the appearance of neurological symptoms. This type of epilepsy is characterized... more
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      Medicinal ChemistryMedicinal chemistry and pharmaceutical chemistryHippocampusTemporal Lobe Epilepsy
Background and objectives The objective of this study was to determine the clinical significance of renal vascular lesions in lupus nephritis. Design, setting, participants, & measurements Renal vascular lesions defined as thrombotic... more
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      Multivariate AnalysisProspective studiesKidneyBlood Pressure