1994.routine thyroid function tests in infertie.tif

Academia Biology, 2024

Spices and Mediterranean medicinal plants provide a rich resource for novel antiviral drug development. The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to a pandemic with devastating outcomes, and hence, there is a global need to search for small-molecule inhibitors that can act against this viral pathogen. This review highlights studies that have investigated the antiviral activities of spices and Mediterranean herbs, as well as their mechanism of action against SARS-CoV-2. Potential therapeutic target mechanisms addressed in this review comprise both host-directed and virus-directed therapies. Host-directed therapies include the inhibition of angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2). Virus-directed therapies include inhibition of papain-like protease (PLpro) and the main protease, 3-chymotrypsin-like protease (3CLpro). Though numerous studies have been conducted on natural products, many of these studies have been performed in silico and require further research to verify the suggested therapeutic properties. 3CLpro has been identified as the target with the largest number of proven in vitro results, with compounds from different classes of molecules shown to inhibit this essential viral protease. In silico studies have confirmed the in vitro results, while providing additional mechanistic insights. Phytocompounds can serve as a foundation for designing new antiviral therapies.

ترجیحات سستمر ۲۰۲۴, 2024

مہجری ادب : مفہوم و معنی مہجری ادب کی جہات اور اردو

Esta dissertação é uma leitura do livro O código das águas (1984) de Lindolf Bell (1938-1998). A pergunta que norteia este texto é: o que é isto, a palavra ?origem?? Para respondê-la, dispõe-se de epistemologia e metodologia provenientes das Ninety-Five Theses on Philology (?Noventa e cinco teses sobre a filologia?) de Werner Hamacher (2015). O caráter ontológico (do questionar sobre o ser do objeto em análise) permanece em segundo plano. Confere-se maior atenção ao percurso que a palavra ?origem? faz ao longo da obra de Lindolf Bell, do que à sua tentativa de construção conceitual. No primeiro livro de Lindolf Bell, Os póstumos e as profecias (1962), a palavra ?origem? não ocorre, vislumbrando-se apenas sua aparição por sinonímia nas palavras ?herança?, ?legado? e na ação de nascer. Por isso, mapeia-se a palavra ?origem?, seus sinônimos e aproximações semânticas, de maneira geral, desde o primeiro livro até O código das águas (1984), demonstrando as tensões e oscilações históricas, intelectuais, semânticas e semióticas no que é pertinente a Lindolf Bell. Em seguida, discuto as possibilidades da palavra ?origem?, e tudo que ela engendra, ser como que a fundamentação do seu fazer poético, em comparação com o que inicialmente se compreendeu, pela crítica, como sendo alicerçado na voz e na performance/mitificação de si. Consequentemente, evidencia-se como no livro se pode ler o estilhaçamento e a renegação de uma concepção de sujeito indivisível. Compreendido, então, como marcas consumidas pelo tempo, e como afirmação de um ausente que não se torna completamente presente mesmo quando empiricamente verificado. Conclui-se que a concepção da palavra ?origem? em O código das águas foi uma tentativa de se tomar a origem como questão, assim como ter a questão basilar como sendo a de um entendimento da palavra origem. Desafiou-se as acepções sincrônicas de ?proveniência?, ?herança? e ?legado?, subvertendo-as como construtos que dizem respeito não apenas à filiação genealógica e ao pertencimento à nação (nas dimensões teológico-políticas), mas à livre invenção do sujeito.

2012

2023

This paper deals with some aspects of Lucan's syntax.

Neotropical Ichthyology, 2019

This paper explores the effects of two run-of-river dams (Jirau and Santo Antônio) built in cascade in the middle Madeira River (Brazil) on the interruption of long-distance migration routes of the gilded catfish (Brachyplatystoma rousseauxii). A participative monitoring system was set up to compare capture by commercial fishers approximately 1500 km upstream of the dams in Bolivia, before (1998-2007) and after (2015-2017) dam closure. A significant decrease in gilded catfish catches and in catch per unit effort was observed after dam closure, whereas no significant difference in mean weight was found. Back-estimation of age suggests that the few individuals remaining after dam closure in 2009 are a mixture of old homers that returned upstream before dam closure, and residents hatched after dam closure and trapped in the upper Madeira. Unless fishways in the Madeira River dams improve their efficiency, the gilded catfish might become rare and in danger of regional extinction in the ...

Montreal Architecture Review, 2019

The Chapelle Notre-Dame-du-Haut in Ronchamp designed by Charles-Edouard Jeanneret, also known as Le Corbusier, has been studied, analyzed and explored by architects, theorists and historians ever since it was completed. Despite these studies, scholars have paid little attention to the east wall of the chapel as a unique architectural element. An important and iconic element within this project, it is distinguished by the turning statue of the Virgin Mary set in a cabinet within the wall and surrounded by small openings allowing light into the chapel. While the moving statue had always been part of the original design, the small openings-the stars-were not. Somehow and sometime the eastern wall became a sky when, at the beginning of construction, it was a wall. The story began with Le Corbusier's slow design process, which allowed him to develop an evolving vision even after a design was finalized. His creative process allowed him to envision the building as a full scale model, which provided him with freedom to take advantage of new opportunities of designing during construction. This occurred with the east wall. A serendipitous * This essay was initially conceived in the late 1990s but developed for and presented at the AHRA conference on models and buildings at Nottingham in November 2005. I wish to thank Lisa Landrum and Margarita McGrath for their recent suggestions, as well as Peter Carl for his generous and extensive comments on the initial paper.

Please feel free contact either or both us if you have any queries: [email protected] [email protected] Proposals open on the 31st January 2017, please go to the following page for this: http://www.eaa2017maastricht.nl/. On the day a link will be available for people to submit their proposals. The variety of standing stone forms and their geographical locations hint that their uses also differed widely. But is this true? How do the associations of megaliths, menhirs and miniliths differ? What material cultural elements do they share and where are they placed? What of circular and linear monuments? Apart from form, in what other ways do these differ, if at all, and what does the difference in form actually mean? Is it really about tectonics and stereotomics (Ingold 2012, 2015)? Or are these forms part of notions of circularity versus rectangularity (Bradley 2012)? What happens when they exist together? In this session, we invite papers that can help answer some of these questions through any kind of comparative assessment or those that use innovative approaches to discern differences in standing stone use or meaning, such as: the inclusion of natural megaliths, digital simulation methods that incorporate palaeo-environmental reconstructions around different site types, entire visualscapes at monuments above and below the horizon, or detailed dating and genetic work. Together, these comparative and innovative approaches should help us to begin to track which peoples were doing what, where, and how their interaction with their natural worlds and their monuments changed over time and possibly why. As well as the usual question time for individual speakers after their presentations, the session leaders will create an overview of the talk themes and results and engage with everyone in further discussion.