Skip to main content
Background: In the nervous system, NG2, an integral membrane chondroitin sulfate proteoglycan, is expressed by macrophages and progenitor glia. Results: Both NG2 shedding and axonal growth depend on the pericellular remodeling executed by... more
    • by  and +2
    •   15  
      MacrophagesBiological ChemistryBiological SciencesNerve Regeneration
Matrix metalloproteinase-9 (MMP-9) is an extracellular protease that is induced hours after injury to peripheral nerve. This study shows that MMP-9 gene deletion and neutralization with MMP-9 antibody reduce macrophage content in injured... more
    • by  and +1
    •   9  
      Cognitive ScienceReal-time RT-PCRTumor necrosis factor-alphaPeripheral Nerve
Background: Myelinating Schwann cells (mSCs) form myelin in the peripheral nervous system. Because of the works by us and others, matrix metalloproteinase-9 (MMP-9) has recently emerged as an essential component of the Schwann cell... more
    • by  and +3
    •   19  
      Comparative StudyMultidisciplinaryCell DifferentiationMice
Background: In the nervous system, NG2, an integral membrane chondroitin sulfate proteoglycan, is expressed by macrophages and progenitor glia. Results: Both NG2 shedding and axonal growth depend on the pericellular remodeling executed by... more
    • by  and +2
    •   15  
      MacrophagesBiological ChemistryBiological SciencesNerve Regeneration
Following peripheral nerve injury, Schwann cells (SCs) vigorously divide to survive and produce a sufficient number of cells to accompany regenerating axons. Matrix metalloproteinases (MMPs) have emerged as modulators of SC signaling and... more
    • by  and +1
    •   17  
      RegenerationGrowthMitosisCell Differentiation
    • by  and +1
    •   21  
      Cognitive ScienceAnimal BehaviorPainApoptosis
To shed light on the early immune response processes in severed peripheral nerve, we performed genome-wide transcriptional profiling and bioinformatics analyses of the proximal (P; regenerating) and distal (D; degenerating) nerve stumps... more
    • by  and +1
    •   12  
      InflammationBiological ChemistryBiological SciencesProtein Kinases
    • by  and +1
A S the world has become more interconnected, the need for coordinated responses to shared global public health threats has increased. A small but growing cadre of diplomats known as health attachés is key among the practitioners of... more
    • by  and +3
    •   5  
      Health SciencesGlobal HealthDiplomacyPublic Health
    • by 
    •   7  
      International RelationsPublic HealthHealth PolicyHarm Reduction
    • by 
    •   20  
      Global HealthInternational CooperationPublic HealthPublic sector
US health care reform includes an abbreviated pathway for follow-on biologics, also known as biosimilars, in an effort to speed up access to these complex therapeutics. However, a key patient safety challenge emerges from such an... more
    • by 
    • Public health systems and services research
Background: Neglected tropical diseases impact over 1 billion of the world's poorest populations and require special attention. However, within the NTDs recognized by the World Health Organization, some are also dually categorized as... more
    • by 
    • by 
    •   7  
      Global HealthPolicyDeveloping CountriesInternational Cooperation
Objective: The threat of non-communicable diseases (''NCDs'') is increasingly becoming a global health crisis and are pervasive in high, middle, and low-income populations resulting in an estimated 36 million deaths per year. There is a... more
    • by 
    •   8  
      EngineeringPhysicsChemistryBiology
Corruption is a serious threat to global health outcomes, leading to financial waste and adverse health consequences. Yet, forms of corruption impacting global health are endemic worldwide in public and private sectors, and in developed... more
    • by 
    • Public health systems and services research
    • by 
    •   6  
      MarketingHealth Care reformMedical OncologyUnited States
    • by 
    •   5  
      Global HealthUnited NationsHealth PolicyWorld Health Organization
Background: Corruption in the health sector can hurt health outcomes. Improving good governance can in turn help prevent health-related corruption. We understand good governance as having the following characteristics: it is... more
    • by  and +1
    •   6  
      Global HealthUnited NationsPublic health systems and services researchHealthy People Programs
    • by 
    •   8  
      Intellectual PropertyHealth PromotionGlobal HealthDeveloping Countries