Papers by Gopalakrishnan Nair
Indian journal of veterinary surgery, 2008
ISRN Veterinary Science, 2011
The present study was carried out to record the occurrence of naturally occurring granulomas in c... more The present study was carried out to record the occurrence of naturally occurring granulomas in cattle and buffaloes. Tissues grossly suspected for granulomas were collected from 336 out of 1600 (21%) abattoir cases. The gross features ranged from focal necrosis to large caseated masses, hard nodules, growths and abscesses. Histopathologically, 102 tissue samples (6.38%) were ascertained as granulomas. Majority of the granulomas were found in the liver 42 (41.18%), followed by lungs 22 (20.59%), lymph nodes 11 (10.78%), kidneys 6 (5.88%) and 14 (13.73%) as subcutaneous nodules/growths. Solitary cases were found in tongue, muscle, and urinary bladder, whereas 4 granulomas (3.92%) were found in body cavities. Based on the cellular component, the granulomas were categorized as epithelioid (53%), eosinophilic (37%) and suppurative (10%). Employing special staining techniques, the possible etiology of 75 granulomas could be identified. Among these, 70 granulomas (68.63%) were of infectio...
To standardize a commercially viable in vitro rooting procedure for banana (Musa paradisiaca L.),... more To standardize a commercially viable in vitro rooting procedure for banana (Musa paradisiaca L.), micro-shoots from three week-old cultures of variety ‘Grand Naine’ were inoculated onto four different mineral salt concentrations of MS (Murashige and Skoog) media supplemented with 2 mg l -1 NAA (�-naphthyleneacetic acid), 20 g l -1 sucrose, 100 mg l -1 activated charcoal and 8 g l -1 agar. After three weeks of incubation, the micro-shoots cultured onto ¾-strength MS media showed the best response in terms of root initiation and growth. After hardening, plantlets developed on ½- or ¾-strength MS medium could be acclimatized and grew well ex vitro. Therefore, low mineral salt concentration in the in vitro rooting media can be adopted as an effective low-cost in vitro rooting procedure for banana ‘Grand Naine’.
Thesis (Ph. D.)--University of Liverpool, 1995.
ISRN veterinary science, 2012
Steroid hormones are found to play a major role in the genesis and progression of mammary tumors.... more Steroid hormones are found to play a major role in the genesis and progression of mammary tumors. The aim of this study was to immunohistochemically detect the presence of estrogen receptor alpha (ER α ), estrogen receptor beta (ER β ), and progesterone receptor (PR) and also to study the association between these markers in 29 cases of benign (11) and malignant (18) canine mammary tumors. ER α immunostaining was noticed in only one case of carcinosarcoma specifically in the nuclei of epithelial and a few myoepithelial cells. ER β immunostaining was noticed in the nuclei and cytoplasm of epithelial cells and smooth muscles lining the blood vessels. Immunoexpression of ER β was 82% in benign tumors and 78% in malignant tumors. PR immunostaining was expressed in the nuclei of epithelial cells in both benign and malignant tumors. Among the 15 PR+ cases, 6 (55%) were of benign type, and 9 (50%) were of malignant type. The most common group of hormone receptor was the ER α -/PR+/ER β + (...
An adult guinea fowl maintained in the poultry farm of the institute died suddenly without manife... more An adult guinea fowl maintained in the poultry farm of the institute died suddenly without manifesting any premonitory clinical signs. On necropsy, highly vascular pedunculated multiple growths were seen on the ovary. The growth, which originated from the ovary, was histopathologically confirmed as adenocarcinoma with transcoelomic spread over the duodenal serosa. An incidence of ovarian adenocarcinoma in guinea fowls and
Toxin Reviews, 1989
ABSTRACT Abstract Hepatic disorders caused by ingestion of aflatoxin contaminated feed were descr... more ABSTRACT Abstract Hepatic disorders caused by ingestion of aflatoxin contaminated feed were described in pigs and ducks. Hepatosis was seen in high proportion of pigs. Experimental studies were conducted in pigs by feeding aflatoxin for a period of three months. There was reduction in feed intake, growth rate and hepatosis. As a result of immunosuppression induced by aflatoxin, pigs developed mange infection. The pathological features of hepatosis encountered in spontaneous cases and experimental cases were described. In ducks as a result of consumption of dietary aflatoxin hepatosis, hepatoma, hepatocellularcarcinoma, cholangiocellular carcinoma were recorded. Tumours in the air sac independently and concomitantly with hepatomas were seen. Detailed histological and histochemical features of the neoplasms were studied. The importance of aflatoxin contaminated feed in causing severe economic loss by way of hepatosis and reduced feed consumption and growth rate was pointed out.
The present study was carried out to record the occurrence of naturally occurring granulomas in c... more The present study was carried out to record the occurrence of naturally occurring granulomas in cattle and buffaloes. Tissues grossly suspected for granulomas were collected from 336 out of 1600 (21%) abattoir cases. The gross features ranged from focal necrosis to large caseated masses, hard nodules, growths and abscesses. Histopathologically, 102 tissue samples (6.38%) were ascertained as granulomas. Majority of the granulomas were found in the liver 42 (41.18%), followed by lungs 22 (20.59%), lymph nodes 11 (10.78%), kidneys 6 (5.88%) and 14 (13.73%) as subcutaneous nodules/growths. Solitary cases were found in tongue, muscle, and urinary bladder, whereas 4 granulomas (3.92%) were found in body cavities. Based on the cellular component, the granulomas were categorized as epithelioid (53%), eosinophilic (37%) and suppurative (10%). Employing special staining techniques, the possible etiology of 75 granulomas could be identified. Among these, 70 granulomas (68.63%) were of infectious nature (parasitic 37 (36.28%), bacterial 32 (31.37%), and fungal 1(0.98%)). Non-infectious granulomas 5 cases (4.90%) included two lipid granulomas (1.96%), two granulomas (1.96%) associated with neoplasms and one (0.31%) associated with renal calculi. In 27 (26.47%) cases, the etiology of the granuloma could not be established and were categorized as granulomas of unknown etiology.
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Papers by Gopalakrishnan Nair