Papers by yilma hunde gonfa
Sustainability, Nov 27, 2022
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Journal of Chemistry, Oct 3, 2022
Cyclospermum leptophyllum is plant species known for its medicinal value and pleasant aroma. e ae... more Cyclospermum leptophyllum is plant species known for its medicinal value and pleasant aroma. e aerial part and plant seeds are traditionally used as food additives as a spice. is study aims to isolate the chemical constituents of essential oil of the aerial part of the plant and study their potential antibacterial activities against some food contaminating bacteria. e essential oil of C. leptophyllum (CSEO) was isolated from aerial parts of the plant species and studied using GC-MS and FTIR techniques. e rst four major chemical constituents determined from GC-MS analysis of CSEO (for peak area % ≥ 1.15%) were 2,5-dimethoxy-p-cymene (87.09%), 2-methoxy-1-methyl-4-(1-methylethyl) benzene (3.09%), 2-methoxy-4-methyl-1-(1-methylethyl) benzene (1.71%), and humulene (1.15%). 60%, 30%, 15%, 7.5%, and 3.75% of CSEO solutions were prepared and evaluated for their potential antibacterial activities against six food spoilage pathogenic bacterial strains. ree Gram-positive strains: Staphylococcus aureus (ATCC 25923), Staphylococcus epidermidis (ATCC 12228), Streptococcus agalactiae (ATCC 12386) and three Gram-negative strains: Escherichia coli (ATCC 25922), Proteus mirabilis (ATCC 35659), and Pseudomonas aeruginosa (ATCC 27853) were used as test microorganisms. Compared to cipro oxacin, a positive control, the promising antibacterial activity was observed for CSEO against S. aureus at minimum and maximum test solutions as the values of the zone of inhibition diameter (ZID, mm) were recorded as 14.33 ± 0.58 for 3.75% CSEO solution and 30.67 ± 0.58 for 60% CSEO solution. Tests of CSEO solutions generally showed stronger antibacterial activities against Gram-positive than Gramnegative strains. erefore, CSEO contains potent chemical constituents that might be applicable in treating pathogenic bacterial species.
Evidence-Based Complementary and Alternative Medicine
Medicinal plants have been treating various ailments and diseases since ancient times. Aquatic an... more Medicinal plants have been treating various ailments and diseases since ancient times. Aquatic and semiaquatic medicinal plants play an essential role in human welfare to fulfill their daily needs. They have shown biological, pharmacological, nutraceutical, and commercial applications. This review aims to collect and update all recent information on ethnomedicinal, phytochemistry, pharmacological activities, and nanoparticle synthesis and their uses in aquatic and semiaquatic medicinal plants. Original research papers, review papers, short communications, and book chapters on aquatic and semiaquatic plants have been retrieved from PubMed, Web of Science, Scopus, and Google Scholar. Keywords, ethnomedicinal studies, phytochemistry, pharmacological activities, and nanoparticle synthesis from aquatic and semiaquatic medicinal plants are used for the search. Different aquatic and semiaquatic medicinal plants belonging to the families Acanthaceae, Alismataceae, Amaranthaceae, Apiaceae, A...
Current Hypertension Reviews, 2012
The pathogenesis and progression of cardiovascular diseases are thought to be exacerbated by stre... more The pathogenesis and progression of cardiovascular diseases are thought to be exacerbated by stress. Basic research indicates that the Transcendental Meditation ® technique produces acute and longitudinal reductions in sympathetic tone and stress reactivity. In adolescents at risk for hypertension, the technique has been found to reduce resting and ambulatory blood pressure, left ventricular mass, cardiovascular reactivity, and to improve school behavior. Research on adults with mild or moderate essential hypertension has reported decreased blood pressure and reduced use of anti-hypertensive medication. The technique has also been reported to decrease symptoms of angina pectoris and carotid atherosclerosis, to reduce cardiovascular risk factors, including alcohol and tobacco use, to markedly reduce medical care utilization for cardiovascular diseases, and to significantly decrease cardiovascular and all-cause morbidity and mortality. These findings have important implications for inclusion of the Transcendental Meditation program in efforts to prevent and treat cardiovascular diseases and their clinical consequences. ® Transcendental Meditation and TM are trademarks registered in the US. Patent and Trademark Office, licensed to Maharishi Vedic Education Development Corporation and are used with permission.
Review article, 2021
Background: Rumex nepalensis, a widely known traditional medicinal plant and is used as the sourc... more Background: Rumex nepalensis, a widely known traditional medicinal plant and is used as the source of medicines and human diet in various communities. Currently, the phytochemical investigation and pharmacological studies of R. nepalensis are of significant research interest. Therefore, the current review is mainly focused on the phytochemical investigation and pharmacological applications of R. nepalensis Main body: Various secondary metabolites like emodin, endocrocin, chrysophanol, neopodin, physcion, torachrysone, aloesin, catechin, quercetin, resveratrol, and their derivatives were isolated from root and aerial parts of the plant. Both isolated compounds and extracts from R. nepalensis are reported to have pharmacological activities such as antiinflammatory, antioxidant, antimicrobial, wound healing, and anti-plasmodial activities Conclusions: Different parts of R. nepalensis have ethnomedicinal importance. R. nepalensis is one of the potential sources of pharmacologically active extracts and isolated compounds. In future R. nepalensis can play a vital role for the preparation of modern drugs.
Beni-Suef University Journal of Basic and Applied Sciences, 2021
Rumex nepalensis, a widely known traditional medicinal plant and is used as the source of medicin... more Rumex nepalensis, a widely known traditional medicinal plant and is used as the source of medicines and human diet in various communities. Currently, the phytochemical investigation and pharmacological studies of R. nepalensis are of significant research interest. Therefore, the current review is mainly focused on the phytochemical investigation and pharmacological applications of R. nepalensis Various secondary metabolites like emodin, endocrocin, chrysophanol, neopodin, physcion, torachrysone, aloesin, catechin, quercetin, resveratrol, and their derivatives were isolated from root and aerial parts of the plant. Both isolated compounds and extracts from R. nepalensis are reported to have pharmacological activities such as anti-inflammatory, antioxidant, antimicrobial, wound healing, and anti-plasmodial activities Different parts of R. nepalensis have ethnomedicinal importance. R. nepalensis is one of the potential sources of pharmacologically active extracts and isolated compounds....
Beni-Suef University Journal of Basic and Applied Sciences, 2021
Rumex nepalensis, a widely known traditional medicinal plant and is used as the source of medicin... more Rumex nepalensis, a widely known traditional medicinal plant and is used as the source of medicines and human diet in various communities. Currently, the phytochemical investigation and pharmacological studies of R. nepalensis are of significant research interest. Therefore, the current review is mainly focused on the phytochemical investigation and pharmacological applications of R. nepalensis Various secondary metabolites like emodin, endocrocin, chrysophanol, neopodin, physcion, torachrysone, aloesin, catechin, quercetin, resveratrol, and their derivatives were isolated from root and aerial parts of the plant. Both isolated compounds and extracts from R. nepalensis are reported to have pharmacological activities such as anti-inflammatory, antioxidant, antimicrobial, wound healing, and anti-plasmodial activities Different parts of R. nepalensis have ethnomedicinal importance. R. nepalensis is one of the potential sources of pharmacologically active extracts and isolated compounds....
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Papers by yilma hunde gonfa