Mesfin Getachew Tadesse

The world's nations are searching for renewable and sustainable energy and fuels due to restricti... more The world's nations are searching for renewable and sustainable energy and fuels due to restrictions on carbon discharges and fossil feedstock shortage.. Biomass is a renewable and sustainable resource; and its conversion is one of the research hotspot areas. This review aims to summarize the evidence gained from different methods of converting lignocellulose materials using heterogeneous catalysts. The review summarizes heterogeneous catalysts like carbon-based sulfonated acids, polymeric acids, metal oxides, and solid and magnetic nature acids, including methods to improve functionality and recyclability. The paper also discusses the approaches for enhancing the efficiency of reactions between heterogeneous catalysts and lignocellulose substrates, like ball-milling, microwave irradiation, solid acid interaction, the effect of hydrogen bonding, and CH-pi (π) bond interaction techniques.

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Anti-inflammatory activity of phytochemicals from medicinal plants and their nanoparticles: A review

Current Research in Biotechnology

Chemical Composition and Biological Activity of Red Algae (Rhodophyta)

CRC Press eBooks, Jun 15, 2023

Synthesis, characterization, and application of nanohybrid formed by mixing carboxylated cellulose nanocrystal and zinc nitrate hexahydrate by precipitation method using Oxytenanthera abyssinica as raw material

Research Square (Research Square), Nov 4, 2022

In this study, cellulose from Oxytenanthera abyssinica was hydrolyzed to create carboxylated cell... more In this study, cellulose from Oxytenanthera abyssinica was hydrolyzed to create carboxylated cellulose nanocrystals in a solution of citric acid and sulfuric acid. Afterward, nanohybrids were synthesized using carboxylated cellulose nanocrystals, zinc nitrate hexahydrate for photocatalytic degradation, and antibacterial and antioxidant properties. The experimental results were characterized using FTIR, XRD, SEM, and UV-Vis spectroscopy. Data from SEM, XRD, DLS, and FTIR spectra showed that ZnO nanoparticles were loaded on carboxylated CNC to form a nanohybrid of CNC/ZnO with mean nanoparticles size of 164.18 nm and size distribution between 94-351 nm. The data showed CNC/ ZnO nanohybrid had higher antibacterial, photocatalytic and antioxidant activities than CNC. The higher antibacterial activity was observed against both grams positive (Klebsiella pneumonia and Escherichia coli) and gram-negative bacteria (Staphylococcus epidermidis and Staphylococcus aureus) with an inhibition zone of 26.00±1.00 to 41.33±1.15 mm in comparison with Cipro oxacin. The maximal amount of methylene blue photodegradation (about 91.52%) was seen after 75 minutes of exposure to a UV lamp. 53.151.03% DPPH radical scavenging actives with IC50 value of 117.66 µm/ml were obtained at 125 µm/ml concentration of CNC/ZnO sample. Biomedical and environmental applications of cellulose are limited by its extremely low antibacterial, photocatalytic, and antioxidant properties. Therefore, this study was done to enhance these properties by synthesizing a nanohybrid of cellulose nanocrystals from cellulose produced from Oxytenanthera abyssinica and ZnO inorganic salt.

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Optimization, Characterization, and Biological Applications of Silver Nanoparticles Synthesized Using Essential Oil of Aerial Part of Laggera tomentosa

Sustainability, 2023

This article is an open access article distributed under the terms and conditions of the Creative... more

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Medicinally Important Plant Roots and Their Role in Nanoparticles Synthesis and Applications

CRC Press eBooks, Apr 5, 2023

Flavonoids and Phenolic Acids from Aerial Part of Ajuga integrifolia (Buch.-Ham. Ex D. Don): Anti-Shigellosis Activity and In Silico Molecular Docking Studies

Molecules, Jan 22, 2023

This article is an open access article distributed under the terms and conditions of the Creative... more

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Synthesis of lignin nanoparticles from Oxytenanthera abyssinica by nanoprecipitation method followed by ultrasonication for the nanocomposite application

Journal of King Saud University - Science

Optimization, Identification, and Quantification of Selected Phenolics in Three Underutilized Exotic Edible Fruits Using HPTLC

Sustainability

This study aimed to investigate selected bioactive components in three underutilized wild edible ... more This study aimed to investigate selected bioactive components in three underutilized wild edible exotic fruits (Syzygium guineense Wild. DC, Ziziphus spina-christi L., and Citrus medica L.), using high-performance thin-layer chromatography and ultraviolet-visible spectrophotometry (HPTLC-UV-Vis), treated under three drying conditions. Ultrasound-assisted extraction was used to extract the target bioactive components under specified conditions, i.e., time of 15 min, temperature of 35 °C, methanol and water 75/25, v/v, and fruit powder-to-solvent ratio of 1:15, w/v. The mobile phase ratio for rutin, kaempferol, myricetin, and quercetin was toluene/ethylacetate/methanol/formic acid at 20:12:8:4, whereas, for phenolic acids, the ratio was 10:15:10:5, respectively. The HPTLC plates were scanned to identify and quantify selected compounds (phenolic acids, quercetin, rutin, myricetin, and kaempferol) at their maximum optimized absorption wavelengths. The contents of target bioactive compon...

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Method optimization for the determinations of selected phytochemicals and antioxidant activities of wild Ethiopian Syzygium guineense fruit and seed under different drying conditions

Heliyon

Medicinally Important Seed Extract and Seed Oil-Mediated Nanoparticles Synthesis and Their Role in Drug Delivery and Other Applications

by Megersa Bedo Megra and Mesfin Getachew Tadesse

CRC Press eBooks, Apr 5, 2023

Medicinally Important Seed Extract and Seed Oil-Mediated Nanoparticles Synthesis and Their Role in Drug Delivery and Other Applications

by meseret zebeaman, Mesfin Getachew Tadesse, and Megersa Bedo Megra

CRC Press eBooks, Apr 5, 2023

Plants and Plant-Derived Molecules as Natural Immunomodulators

BioMed Research International

Background. Nowadays, the immunomodulatory properties of plants have been studied extensively wit... more Background. Nowadays, the immunomodulatory properties of plants have been studied extensively with greater interest due to increasing awareness and combating the severity of immunomodulatory diseases. Scope and Approach. This paper highlights the efficacy of the available literature evidence on natural immunomodulators of plant origin and synthetic ones. In addition, several aspects of plants and their phytoconstituents responsible for immunomodulation have been discussed. Moreover, this review also discusses the mechanism involved in immunomodulation. Key Findings. One hundred fifty medicinal immunomodulatory plants are currently identified to find novel immunomodulatory drugs. Of these plants, the plant family Asteraceae also takes the first rank by offering 18 plant species (12%). Similarly of the plants studied so far, 40% belong to the Asteraceae family. Echinacea purpurea of this family is most known for its immunostimulating activity. The most prominent immune-active bioactiv...

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Medicinally Important Seed Extract and Seed Oil-Mediated Nanoparticles Synthesis and Their Role in Drug Delivery and Other Applications

CRC Press eBooks, Apr 5, 2023