2018 IEEE Wireless Communications and Networking Conference (WCNC)
In this paper, we propose a novel wireless-powered hybrid (downlink and uplink) NOMA system to fa... more In this paper, we propose a novel wireless-powered hybrid (downlink and uplink) NOMA system to facilitate uplink NOMA transmission on the basis of harvested energy from radio frequencies. Particularly, this scheme enables the users to maintain distinguished power levels in communicating back to the source utilising NOMA, hence allowing source to extract received messages successfully. By assuming that the two users are located at different locations, analytical expressions of the outage probabilities of the users involved in this scheme are derived. Monte Carlo simulations are performed to validate the accuracy of the developed analytical model. It is clear from the results that wireless power transfer can be used successfully in uplink NOMA transmission in case when the users are running out of power, providing successful communication between users and the source.
Zaidi et al. This is an open access article distributed under the terms of the Creative Commons A... more Zaidi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
ICC 2019 - 2019 IEEE International Conference on Communications (ICC)
In order to enhance the capacity of the Fifth Generation and beyond (5GB) cellular networks, thir... more In order to enhance the capacity of the Fifth Generation and beyond (5GB) cellular networks, third generation partnership project (3GPP) has provided guidelines for enabling device-to-device (D2D) communication. An essential requirement for successful D2D communication is the users' ability to discover each other, specially in the out-of-network scenarios. While there has been some research effort in the area of D2D discovery, most of the works assume that the devices are static. In a typical mobile environment, the constraints like time-to-discovery, etc, are more rigid and deserve investigation. This paper formulates a mathematical model for a mobile device's neighborhood discovery as it moves across an area that has other D2D users. In particular, we determine the expected number of users discovered by a mobile device while moving in a straight line between two way-points following random waypoint mobility. The model is verified using Monte-Carlo simulation and can be used for future analysis of mobile D2D-discovery.
2017 IEEE 28th Annual International Symposium on Personal, Indoor, and Mobile Radio Communications (PIMRC)
In a conventional Cooperative Non Orthogonal Multiple Access (NOMA) scheme, only one user from th... more In a conventional Cooperative Non Orthogonal Multiple Access (NOMA) scheme, only one user from the NOMA pair acts as a relay and forwards information to the other user. In this paper, we aim to introduce NOMA-based relaying to extend the coverage of the source and serve the remote devices in out-of-coverage area. This extension in coverage is supported by powering the relays wirelessly with the help of simultaneous energy transfer so that the relays can self-sustain within the network without utilising their individual power. The closed-form expressions for outage probabilities of the downlink messages from source to the remote users and downlink throughput are derived. The proposed results confirm that this scheme successfully utilises wireless-powered NOMA relays in delivering the information of the source to remotely located users.
Introduction: Psychological issues are common in patients with spinal cord injury (SCI) which neg... more Introduction: Psychological issues are common in patients with spinal cord injury (SCI) which negatively affects rehabilitation outcomes. Therefore, early psychological interventions are as important as physical rehabilitation. The aim of the study was to systematically review literature regarding the effects of psychological interventions on rehabilitation outcomes in patients with SCI. Material & Methods: A systematic review was conducted according to the PRISMA guidelines. Literature was searched in PubMed and PEDro databases. Articles published in English language from earliest record to August 2020 were searched. Observational and interventional studies which assessed effects of different psychological interventions on rehabilitation outcomes in patients with SCI were included. Review articles, editorials, short communications and conference papers were excluded. Quality assessment of the interventional studies was assessed using PEDro scale while methodological quality of the ...
This paper is based on a study that was designed to study the "Impact of Anxiety on the Acad... more This paper is based on a study that was designed to study the "Impact of Anxiety on the Academic Achievement of Students at University level in Bahawalpur, Pakistan." Being a descriptive study, survey method was adopted for data collection to find out the results. For sample size out of 200 students 97 students were selected by stratified sampling. The researcher made three groups of all the students and three groups of male and female students. In this research questionnaire (Otis selfadministering test of mental ability) and anxiety measurement scale was selected as an instrument for the purpose of data collection. Data was analyzed by using the formula of regression to see the impact of anxiety on the academic achievements of students and formula of co-relation was applied to see the relationship of anxiety and academic achievements of students in SPSS software. The in depth investigation of the findings obtained through this analyzed data reeals that anxiety had its im...
Extending from our first two studies examining the IGF profile (IGF-1, IGFBP-3 and the ratio of I... more Extending from our first two studies examining the IGF profile (IGF-1, IGFBP-3 and the ratio of IGFBP-3/ IGF-1) in women presenting for assisted reproductive technologies (ART), this study examines its relevance to the testing of human growth hormone (hGH) levels on the same blood sample. These were taken in the morning during the early follicular phase of the woman’s menstrual cycle and included 408 women who were ART-naïve, undertaking the tests as part of an assessment cycle prior to any ART treatment. The growth hormone levels were also tested on a further 945 women classified as ART-interval cases. It was shown that the vast majority of hGH levels (73%) were very low at <1.0 ng/mL and 22% are extremely low <0.1 ng/mL, close to the detection level of the chemiluminescent immunoassay (0.03 ng/mL). Only 12% of hGH levels were recorded in the range ≥3.0 ng/mL, levels which exclude adult growth hormone deficiency (AGHD). Although IGF-1 levels are regarded as a screening test f...
Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering
Broadband availability is an important asset for deriving change in the societal and economic dev... more Broadband availability is an important asset for deriving change in the societal and economic development of a country. New Zealand’s rural areas have limited broadband connectivity and there are some beautiful tourist destinations which do not have broadband availability on site. In this paper, we aim to provide a broadband connectivity model for basic and high speed data services for the area of Makaraka in the Gisborne region of New Zealand. The model proposes the placement of the access points, their channel selection scheme, transmit power requirements and appropriate installation height in detail for different frequency bands and data rate requirements. It is evident from the simulated results that outdoor area of Makaraka is able to get broadband connectivity which will help NZ to drive towards the theme of highly-connected society.
Patient: Female, 26-year-old Final Diagnosis: Intussusception Symptoms: Abdominal pain • nausea M... more Patient: Female, 26-year-old Final Diagnosis: Intussusception Symptoms: Abdominal pain • nausea Medication: — Clinical Procedure: CT scan • surgery Specialty: Gastroenterology and Hepatology • General and Internal Medicine • Surgery Objective: Unusual clinical course Background: Intussusception is a common phenomenon in children, but it is rare in adults. In the pediatric population, the presentation is commonly primary, without a lead point. However, up to 90% of intussusception cases arise due to a secondary cause – a pathological lead point – which the most common etiology in adults being malignancy. Herein, we present a case report of adult intussusception without a known cause. Case Report: A 26-year-old woman presented to the hospital with severe abdominal pain. She admitted to not passing stool or gas for 2 days. The patient’s social history was significant for chronic marijuana use. A computed tomography (CT) scan of the abdomen revealed a 6-cm in length intussuscepted segment of bowel in the descending colon distal to the splenic flexure with no obvious inciting mass. The patient was sent for emergent open abdominal surgery. Upon surgical exploration, the surgeons discovered that the intussusception had self-resolved. Aside from a small ball of stool, an intraoperative colonoscopy revealed no masses or polyps. Conclusions: Marijuana use is known to disrupt gastrointestinal (GI) mobility through receptors in the GI tract nerve plexuses. The incidence of chronic marijuana use and adult intussusception is documented in the literature. Conservative management with bowel rest is confirmed to be a suitable treatment option with a favorable outcome. Therefore, we present this case to increase awareness of the potential adverse effects of chronic marijuana use, and to prevent invasive treatment.
2018 Eleventh International Conference on Mobile Computing and Ubiquitous Network (ICMU)
Simultaneous Wireless Information and Power transfer (SWIPT) is a technique that allows energy ha... more Simultaneous Wireless Information and Power transfer (SWIPT) is a technique that allows energy harvesting and processing of the received data at the same time. If these two tasks are done one-by-one, SWIPT is said to be using time switching (TS) mechanism. TS is a unique way of mutually scavenging energy and transferring information by slicing the time into two slots for achieving the energy harvesting and information transmission goals together. This paper examines the performance of TS-based SWIPT in a wireless network, where an out-of-coverage user is served utilising Non-Orthogonal Multiple Access (NOMA) technique. NOMA is an evolving power domain multiplexing scheme which combines signals within same frequency/time band by varying power levels for transmission. We consider a relaying environment, where a NOMA based near user is incentivised with energy for transferring the data to a remote user. The performance of our proposed system is evaluated by deriving the expressions for the outage probabilities of all users and the system throughput. The results which are also validated by Monte Carlo simulations, show that the proposed system performs well along and provides additional coverage to a far-located user.
Gentamicin (GM) is a generally utilized as an antibiotic against dangerous and life threatening c... more Gentamicin (GM) is a generally utilized as an antibiotic against dangerous and life threatening contaminations, yet its value is restricted by the development of nephrotoxicity. The present investigation was intended to decide the defensive impact of salicylic acid (SA) in gentamicin-induced nephrotoxicity in rabbits. Quantitative assessment of gentamicin-induced structural changes and level of functional modifications in the kidneys were performed by biochemical examinations keeping in mind the end goal is to decide the potential protective impacts of SA co-administration with gentamicin. Gentamicin was seen to cause a serious nephrotoxicity which was proved by a plasma urea, plasmacreatinine, plasma uric acid, plasma Na+, plasma K+, intra-erythrocyte Na+ and intra-erythrocyte K+ levels. On the other hand, simultaneous SA administration protected kidney tissue against the oxidative damage and the nephrotoxic effect caused by GM treatment. The outcomes from our investigation show th...
2019 29th International Telecommunication Networks and Applications Conference (ITNAC)
Unmanned aerial vehicles (UAVs) are gaining recognition as aerial base station and as relays to p... more Unmanned aerial vehicles (UAVs) are gaining recognition as aerial base station and as relays to provide coverage in fifth-generation and beyond networks. With a multitude of devices present in future wireless networks, a ground or an aerial device, both can act as a relay for coverage extension. We propose to utilise either ground or aerial device as a relay based on the channel characteristics of the device with transmit source. Non-orthogonal multiple access (NOMA) is enforced to pair the ground and aerial device. In our scheme, a device which establishes strong communication link with transmit source is selected as a relay. The relay communication is further fuelled by harvesting energy from the radio signals of transmit source using power-splitting energy harvesting protocol. It is shown that the channel fading characteristics and path-loss environment of a ground and aerial user which are different in nature, contribute towards the relay selection. The results indicate that the proposed scheme achieves improved signal reception at the end user with the use of this dynamic relaying scheme.
Availability of economical quality medicines is always required for chronic disease management. P... more Availability of economical quality medicines is always required for chronic disease management. Price differences among multiple brands of a product do not essentially displays low quality for the more affordable brand, however in a few occurrences it appears. Glimepiride, an oral anti-diabetic drug, is produced by several national and multinational industries in Pakistan with considerable cost variation. The study aimed to evaluate the quality and economy of various Glimepiride brands available in Karachi, specifically of public sector hospitals. For this, eight glimepiride brands were collected and analyzed for the pharmaceutical quality using physical parameters, disintegration test, dissolution profile, spectrophotometric assay and content uniformity. Pharmacoeconomic assessment was also carried out such as availability, affordability and price variation. A profound discrepancy was observed among the prices of selected brands. All of the products found to be equivalent to the re...
Stevens-Johnson syndrome (SJS) is an immune mediated hypersensitivity reaction. Significant invol... more Stevens-Johnson syndrome (SJS) is an immune mediated hypersensitivity reaction. Significant involvement of oral, nasal, eye, vaginal, urethral, GI and lower respiratory tract mucous membrane may develop. It is usually a reaction due to a medication or due to an infection. In 95 % of case reports, drugs were found to be an important cause for the development of SJS. In this case report, a 32 year old female reported chief complaint of itch skin eruptions all over the body along with erosive lesions on tongue, lips, buccal mucosa and genital mucosa. The reaction occurred after administration of augmentin (containing amoxycillin and clavulanic acid). She was treated with antimicrobials, antiallergics and conservative management. The patient improved and was discharged from the hospital. Causality assessment using Naranjo Adverse Drug Reaction Probability Scale revealed that amoxycillin and clavulanic acid combination was a possible cause for the adverse reaction with a score of 4.
The present research work was designed to evaluate the effects of curcumin supplementation on var... more The present research work was designed to evaluate the effects of curcumin supplementation on various biochemical parameters in rats with thioacetamide (TAA) induced liver cirrhosis. For this purpose 24 male Albino Wistar rats were randomly distributed into four groups (n=6).Group I served as control, Group II and Group III received thioacetamide 200mg/kg b.w, i.p, twice a week for 12 weeks in first phase. In second phase Group II received saline and Group III received curcumin 50mg/kg b.w/day, i.p for 12 weeks, in second phase, Group IV received curcumin 50mg/kg b.w/day, i.p, for 12 weeks, in first phase and saline in second phase. Evaluation of histopathological and biochemical parameters was carried out by liver histopathology and estimation of total and direct bilirubin, liver specific enzymes, antioxidant enzymes, MDA level, plasma and intraerythrocyte sodium and potassium respectively. Histopathology of liver showed highest degree of fibrosis and nodule formation, significant ...
Background: Methotrexate is used in several heterogenic inflammatory and malignant disorders but ... more Background: Methotrexate is used in several heterogenic inflammatory and malignant disorders but life-sustaining liver organ is inevitably predisposed to damage by it. Carvedilol demonstrates anti-oxidant characteristic. The objective of this study was to explore the probable hepatic benefit it might provide when used concomitantly with methotrexate in rats. Methods: It was a laboratory-based randomized control trial done with collaborated effort of Pharmacology and Pathology Department, Army Medical College Rawalpindi along with National Institute of Health Islamabad, from March to July 2018. A total of 18 Sprague Dawley rats were randomly divided into 3 groups with 6 rats each. Untreated Group-I served as standard. On 7th and 14th day, 20 mg/Kg intraperitoneal methotrexate injection was given to rats in Group-II, while Group-III received carvedilol (10 mg/Kg/day) per-orally throughout with methotrexate intervention in-between. Blood was drawn for evaluation of liver function tests...
Glucocorticoid excess is an under-recognised cause of cardiovascular adverse effects. The sources... more Glucocorticoid excess is an under-recognised cause of cardiovascular adverse effects. The sources can be either endogenous (Cushing’s syndrome) or exogenous (Anabolic steroid abuse). Cardiovascular complications due to excess glucocorticoid includes hypertension, left ventricular hypertrophy, myocardial infarction, and heart failure. Although anabolic steroid-induced cardiomyopathy is a well-recognised phenomenon, endogenous corticosteroid-induced cardiomyopathy and heart failure are rarely reported sequelae of glucocorticoid excess in the body. We report a glucocorticoid-induced dilated cardiomyopathy in a 26-year-old African–American man with cushingoid features and symptomatic heart failure.
2018 IEEE Wireless Communications and Networking Conference (WCNC)
In this paper, we propose a novel wireless-powered hybrid (downlink and uplink) NOMA system to fa... more In this paper, we propose a novel wireless-powered hybrid (downlink and uplink) NOMA system to facilitate uplink NOMA transmission on the basis of harvested energy from radio frequencies. Particularly, this scheme enables the users to maintain distinguished power levels in communicating back to the source utilising NOMA, hence allowing source to extract received messages successfully. By assuming that the two users are located at different locations, analytical expressions of the outage probabilities of the users involved in this scheme are derived. Monte Carlo simulations are performed to validate the accuracy of the developed analytical model. It is clear from the results that wireless power transfer can be used successfully in uplink NOMA transmission in case when the users are running out of power, providing successful communication between users and the source.
Zaidi et al. This is an open access article distributed under the terms of the Creative Commons A... more Zaidi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
ICC 2019 - 2019 IEEE International Conference on Communications (ICC)
In order to enhance the capacity of the Fifth Generation and beyond (5GB) cellular networks, thir... more In order to enhance the capacity of the Fifth Generation and beyond (5GB) cellular networks, third generation partnership project (3GPP) has provided guidelines for enabling device-to-device (D2D) communication. An essential requirement for successful D2D communication is the users' ability to discover each other, specially in the out-of-network scenarios. While there has been some research effort in the area of D2D discovery, most of the works assume that the devices are static. In a typical mobile environment, the constraints like time-to-discovery, etc, are more rigid and deserve investigation. This paper formulates a mathematical model for a mobile device's neighborhood discovery as it moves across an area that has other D2D users. In particular, we determine the expected number of users discovered by a mobile device while moving in a straight line between two way-points following random waypoint mobility. The model is verified using Monte-Carlo simulation and can be used for future analysis of mobile D2D-discovery.
2017 IEEE 28th Annual International Symposium on Personal, Indoor, and Mobile Radio Communications (PIMRC)
In a conventional Cooperative Non Orthogonal Multiple Access (NOMA) scheme, only one user from th... more In a conventional Cooperative Non Orthogonal Multiple Access (NOMA) scheme, only one user from the NOMA pair acts as a relay and forwards information to the other user. In this paper, we aim to introduce NOMA-based relaying to extend the coverage of the source and serve the remote devices in out-of-coverage area. This extension in coverage is supported by powering the relays wirelessly with the help of simultaneous energy transfer so that the relays can self-sustain within the network without utilising their individual power. The closed-form expressions for outage probabilities of the downlink messages from source to the remote users and downlink throughput are derived. The proposed results confirm that this scheme successfully utilises wireless-powered NOMA relays in delivering the information of the source to remotely located users.
Introduction: Psychological issues are common in patients with spinal cord injury (SCI) which neg... more Introduction: Psychological issues are common in patients with spinal cord injury (SCI) which negatively affects rehabilitation outcomes. Therefore, early psychological interventions are as important as physical rehabilitation. The aim of the study was to systematically review literature regarding the effects of psychological interventions on rehabilitation outcomes in patients with SCI. Material & Methods: A systematic review was conducted according to the PRISMA guidelines. Literature was searched in PubMed and PEDro databases. Articles published in English language from earliest record to August 2020 were searched. Observational and interventional studies which assessed effects of different psychological interventions on rehabilitation outcomes in patients with SCI were included. Review articles, editorials, short communications and conference papers were excluded. Quality assessment of the interventional studies was assessed using PEDro scale while methodological quality of the ...
This paper is based on a study that was designed to study the "Impact of Anxiety on the Acad... more This paper is based on a study that was designed to study the "Impact of Anxiety on the Academic Achievement of Students at University level in Bahawalpur, Pakistan." Being a descriptive study, survey method was adopted for data collection to find out the results. For sample size out of 200 students 97 students were selected by stratified sampling. The researcher made three groups of all the students and three groups of male and female students. In this research questionnaire (Otis selfadministering test of mental ability) and anxiety measurement scale was selected as an instrument for the purpose of data collection. Data was analyzed by using the formula of regression to see the impact of anxiety on the academic achievements of students and formula of co-relation was applied to see the relationship of anxiety and academic achievements of students in SPSS software. The in depth investigation of the findings obtained through this analyzed data reeals that anxiety had its im...
Extending from our first two studies examining the IGF profile (IGF-1, IGFBP-3 and the ratio of I... more Extending from our first two studies examining the IGF profile (IGF-1, IGFBP-3 and the ratio of IGFBP-3/ IGF-1) in women presenting for assisted reproductive technologies (ART), this study examines its relevance to the testing of human growth hormone (hGH) levels on the same blood sample. These were taken in the morning during the early follicular phase of the woman’s menstrual cycle and included 408 women who were ART-naïve, undertaking the tests as part of an assessment cycle prior to any ART treatment. The growth hormone levels were also tested on a further 945 women classified as ART-interval cases. It was shown that the vast majority of hGH levels (73%) were very low at <1.0 ng/mL and 22% are extremely low <0.1 ng/mL, close to the detection level of the chemiluminescent immunoassay (0.03 ng/mL). Only 12% of hGH levels were recorded in the range ≥3.0 ng/mL, levels which exclude adult growth hormone deficiency (AGHD). Although IGF-1 levels are regarded as a screening test f...
Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering
Broadband availability is an important asset for deriving change in the societal and economic dev... more Broadband availability is an important asset for deriving change in the societal and economic development of a country. New Zealand’s rural areas have limited broadband connectivity and there are some beautiful tourist destinations which do not have broadband availability on site. In this paper, we aim to provide a broadband connectivity model for basic and high speed data services for the area of Makaraka in the Gisborne region of New Zealand. The model proposes the placement of the access points, their channel selection scheme, transmit power requirements and appropriate installation height in detail for different frequency bands and data rate requirements. It is evident from the simulated results that outdoor area of Makaraka is able to get broadband connectivity which will help NZ to drive towards the theme of highly-connected society.
Patient: Female, 26-year-old Final Diagnosis: Intussusception Symptoms: Abdominal pain • nausea M... more Patient: Female, 26-year-old Final Diagnosis: Intussusception Symptoms: Abdominal pain • nausea Medication: — Clinical Procedure: CT scan • surgery Specialty: Gastroenterology and Hepatology • General and Internal Medicine • Surgery Objective: Unusual clinical course Background: Intussusception is a common phenomenon in children, but it is rare in adults. In the pediatric population, the presentation is commonly primary, without a lead point. However, up to 90% of intussusception cases arise due to a secondary cause – a pathological lead point – which the most common etiology in adults being malignancy. Herein, we present a case report of adult intussusception without a known cause. Case Report: A 26-year-old woman presented to the hospital with severe abdominal pain. She admitted to not passing stool or gas for 2 days. The patient’s social history was significant for chronic marijuana use. A computed tomography (CT) scan of the abdomen revealed a 6-cm in length intussuscepted segment of bowel in the descending colon distal to the splenic flexure with no obvious inciting mass. The patient was sent for emergent open abdominal surgery. Upon surgical exploration, the surgeons discovered that the intussusception had self-resolved. Aside from a small ball of stool, an intraoperative colonoscopy revealed no masses or polyps. Conclusions: Marijuana use is known to disrupt gastrointestinal (GI) mobility through receptors in the GI tract nerve plexuses. The incidence of chronic marijuana use and adult intussusception is documented in the literature. Conservative management with bowel rest is confirmed to be a suitable treatment option with a favorable outcome. Therefore, we present this case to increase awareness of the potential adverse effects of chronic marijuana use, and to prevent invasive treatment.
2018 Eleventh International Conference on Mobile Computing and Ubiquitous Network (ICMU)
Simultaneous Wireless Information and Power transfer (SWIPT) is a technique that allows energy ha... more Simultaneous Wireless Information and Power transfer (SWIPT) is a technique that allows energy harvesting and processing of the received data at the same time. If these two tasks are done one-by-one, SWIPT is said to be using time switching (TS) mechanism. TS is a unique way of mutually scavenging energy and transferring information by slicing the time into two slots for achieving the energy harvesting and information transmission goals together. This paper examines the performance of TS-based SWIPT in a wireless network, where an out-of-coverage user is served utilising Non-Orthogonal Multiple Access (NOMA) technique. NOMA is an evolving power domain multiplexing scheme which combines signals within same frequency/time band by varying power levels for transmission. We consider a relaying environment, where a NOMA based near user is incentivised with energy for transferring the data to a remote user. The performance of our proposed system is evaluated by deriving the expressions for the outage probabilities of all users and the system throughput. The results which are also validated by Monte Carlo simulations, show that the proposed system performs well along and provides additional coverage to a far-located user.
Gentamicin (GM) is a generally utilized as an antibiotic against dangerous and life threatening c... more Gentamicin (GM) is a generally utilized as an antibiotic against dangerous and life threatening contaminations, yet its value is restricted by the development of nephrotoxicity. The present investigation was intended to decide the defensive impact of salicylic acid (SA) in gentamicin-induced nephrotoxicity in rabbits. Quantitative assessment of gentamicin-induced structural changes and level of functional modifications in the kidneys were performed by biochemical examinations keeping in mind the end goal is to decide the potential protective impacts of SA co-administration with gentamicin. Gentamicin was seen to cause a serious nephrotoxicity which was proved by a plasma urea, plasmacreatinine, plasma uric acid, plasma Na+, plasma K+, intra-erythrocyte Na+ and intra-erythrocyte K+ levels. On the other hand, simultaneous SA administration protected kidney tissue against the oxidative damage and the nephrotoxic effect caused by GM treatment. The outcomes from our investigation show th...
2019 29th International Telecommunication Networks and Applications Conference (ITNAC)
Unmanned aerial vehicles (UAVs) are gaining recognition as aerial base station and as relays to p... more Unmanned aerial vehicles (UAVs) are gaining recognition as aerial base station and as relays to provide coverage in fifth-generation and beyond networks. With a multitude of devices present in future wireless networks, a ground or an aerial device, both can act as a relay for coverage extension. We propose to utilise either ground or aerial device as a relay based on the channel characteristics of the device with transmit source. Non-orthogonal multiple access (NOMA) is enforced to pair the ground and aerial device. In our scheme, a device which establishes strong communication link with transmit source is selected as a relay. The relay communication is further fuelled by harvesting energy from the radio signals of transmit source using power-splitting energy harvesting protocol. It is shown that the channel fading characteristics and path-loss environment of a ground and aerial user which are different in nature, contribute towards the relay selection. The results indicate that the proposed scheme achieves improved signal reception at the end user with the use of this dynamic relaying scheme.
Availability of economical quality medicines is always required for chronic disease management. P... more Availability of economical quality medicines is always required for chronic disease management. Price differences among multiple brands of a product do not essentially displays low quality for the more affordable brand, however in a few occurrences it appears. Glimepiride, an oral anti-diabetic drug, is produced by several national and multinational industries in Pakistan with considerable cost variation. The study aimed to evaluate the quality and economy of various Glimepiride brands available in Karachi, specifically of public sector hospitals. For this, eight glimepiride brands were collected and analyzed for the pharmaceutical quality using physical parameters, disintegration test, dissolution profile, spectrophotometric assay and content uniformity. Pharmacoeconomic assessment was also carried out such as availability, affordability and price variation. A profound discrepancy was observed among the prices of selected brands. All of the products found to be equivalent to the re...
Stevens-Johnson syndrome (SJS) is an immune mediated hypersensitivity reaction. Significant invol... more Stevens-Johnson syndrome (SJS) is an immune mediated hypersensitivity reaction. Significant involvement of oral, nasal, eye, vaginal, urethral, GI and lower respiratory tract mucous membrane may develop. It is usually a reaction due to a medication or due to an infection. In 95 % of case reports, drugs were found to be an important cause for the development of SJS. In this case report, a 32 year old female reported chief complaint of itch skin eruptions all over the body along with erosive lesions on tongue, lips, buccal mucosa and genital mucosa. The reaction occurred after administration of augmentin (containing amoxycillin and clavulanic acid). She was treated with antimicrobials, antiallergics and conservative management. The patient improved and was discharged from the hospital. Causality assessment using Naranjo Adverse Drug Reaction Probability Scale revealed that amoxycillin and clavulanic acid combination was a possible cause for the adverse reaction with a score of 4.
The present research work was designed to evaluate the effects of curcumin supplementation on var... more The present research work was designed to evaluate the effects of curcumin supplementation on various biochemical parameters in rats with thioacetamide (TAA) induced liver cirrhosis. For this purpose 24 male Albino Wistar rats were randomly distributed into four groups (n=6).Group I served as control, Group II and Group III received thioacetamide 200mg/kg b.w, i.p, twice a week for 12 weeks in first phase. In second phase Group II received saline and Group III received curcumin 50mg/kg b.w/day, i.p for 12 weeks, in second phase, Group IV received curcumin 50mg/kg b.w/day, i.p, for 12 weeks, in first phase and saline in second phase. Evaluation of histopathological and biochemical parameters was carried out by liver histopathology and estimation of total and direct bilirubin, liver specific enzymes, antioxidant enzymes, MDA level, plasma and intraerythrocyte sodium and potassium respectively. Histopathology of liver showed highest degree of fibrosis and nodule formation, significant ...
Background: Methotrexate is used in several heterogenic inflammatory and malignant disorders but ... more Background: Methotrexate is used in several heterogenic inflammatory and malignant disorders but life-sustaining liver organ is inevitably predisposed to damage by it. Carvedilol demonstrates anti-oxidant characteristic. The objective of this study was to explore the probable hepatic benefit it might provide when used concomitantly with methotrexate in rats. Methods: It was a laboratory-based randomized control trial done with collaborated effort of Pharmacology and Pathology Department, Army Medical College Rawalpindi along with National Institute of Health Islamabad, from March to July 2018. A total of 18 Sprague Dawley rats were randomly divided into 3 groups with 6 rats each. Untreated Group-I served as standard. On 7th and 14th day, 20 mg/Kg intraperitoneal methotrexate injection was given to rats in Group-II, while Group-III received carvedilol (10 mg/Kg/day) per-orally throughout with methotrexate intervention in-between. Blood was drawn for evaluation of liver function tests...
Glucocorticoid excess is an under-recognised cause of cardiovascular adverse effects. The sources... more Glucocorticoid excess is an under-recognised cause of cardiovascular adverse effects. The sources can be either endogenous (Cushing’s syndrome) or exogenous (Anabolic steroid abuse). Cardiovascular complications due to excess glucocorticoid includes hypertension, left ventricular hypertrophy, myocardial infarction, and heart failure. Although anabolic steroid-induced cardiomyopathy is a well-recognised phenomenon, endogenous corticosteroid-induced cardiomyopathy and heart failure are rarely reported sequelae of glucocorticoid excess in the body. We report a glucocorticoid-induced dilated cardiomyopathy in a 26-year-old African–American man with cushingoid features and symptomatic heart failure.
Uploads
Papers by syeda zaidi