B SC Chemistry

Semester-wise Titles of the Papers in B.Sc.
Chemistry
Year Sem. Course Code Paper Title Theory/Practical Credits
Certificate in Bioorganic and Medicinal Chemistry
1 I B020101T Fundamentals of Chemistry Theory 4
B020102P Quantitative Analysis Practical 2
II B020201T Bioorganic and Medicinal Chemistry Theory 4
B020202P Biochemical Analysis Practical 2
Diploma in Chemical Dynamics and Analytical Techniques
2 III B020301T Chemical Dynamics & Coordination Theory 4
Chemistry
B020302P Physical Analysis Practical 2
IV B020401T Quantum Mechanics and Analytical Theory 4
Techniques
B020402P Instrumental Analysis Practical 2
Degree in Bachelor of Science
3 V B020501T Organic Synthesis-A Theory 4
B020502T Rearrangements and Chemistry of Group Theory 4
Elements
B020503P Qualitative Analysis Practical 2
B020504R Research Project Project 3
VI B020601T Organic Synthesis-B Theory 4
B020602T Chemical Energetics and Theory 4
Radiochemistry
B020603P Analytical Methods Practical 2
Purpose of the Program

The purpose of the undergraduate chemistry program at the university and college level is to provide the key
knowledge base and laboratory resources to prepare students for careers as professionals in various industries and
research institutions.
Program’s Outcomes
1. Students will have a firm foundation in the fundamentals and application of current chemical and scientific
theories including those in analytical, Inorganic, Organic and Physical Chemistries.
2. Students will be able to design and carry out scientific experiments as well as accurately record and
analyze the results of such experiments.
3. Students will be skilled in problem solving, critical thinking and analytical reasoning as applied to
scientific problems.
4. Students will be able to explore new areas of research in both chemistry and allied fields of science and
technology.
5. Students will appreciate the central role of chemistry in our society and use this as a basis for ethical
behavior in issues facing chemists including an understanding of safe handling of chemicals,
environmental issues and key issues facing our society in energy, health and medicine.
6. Students will be able to explain why chemistry is an integral activity for addressing social, economic, and
environmental problems.
7. Students will be able to function as a member of an interdisciplinary problem solving team.
3
PROGRAM SPECIFIC OUTCOMES (PSOS)
CERTIFICATE IN BIOORGANIC AND MEDICINAL CHEMISTRY

First Certificate in Bioorganic and Medicinal Chemistry will give the student a basic knowledge of all the
Year fundamental principles of chemistry like molecular polarity , bonding theories of molecules, Periodic
properties of more than 111 elements, mechanism of organic Reactions, Stereochemistry, basic
mathematical concepts and computer knowledge, chemistry of carbohydrates, proteins and nucleic acids:
medicinal chemistry, synthetic polymers, synthetic dyes, Student will be able to do to qualitative quantitative
and bio chemical analysis of the compounds in the laboratory. This certificate course is definitely going to
prepare the students for various fields of chemistry and will give an insight into all the branches of chemistry
and enable our students to join the knowledge and available opportunities related to chemistry in the
government and private sector services particularly in the field of food safety, health inspector, pharmacist
etc. Have a broad foundation in chemistry that stresses scientific reasoning and analytical problem solving
with a molecular perspective.
Second DIPLOMA IN CHEMICAL DYNAMICS AND ANALYTICAL TECHNIQUES
Year
Diploma in Chemical Dynamics and Analytical Techniques will provide the theoretical as well as practical
knowledge of handling chemicals, apparatus, equipment and instruments. The knowledge about feasibility
and velocity of chemical reactions through chemical kinetics, chemical equilibrium ,phase equilibrium,
kinetic theories of Gases ,solid and liquid states, coordination chemistry, metal carbonyls and bioinorganic
will enable the students to work as chemists in pharmaceutical industries.
The knowledge about atomic structure, quantum mechanics, various spectroscopic tools and separation
technique will make the students skilled to work in industries: Achieved the skills required to succeed in the
chemical industry like cement industries, agro product, paint industries, rubber industries, petrochemical
industries, food processing industries, Fertilizer industries, pollution monitoring and control agencies etc. Got
exposures of a breadth of experimental techniques using modern instrumentation
Learn the laboratory skills and safely measurements to transfer and interpret knowledge entirely in the working
environment. monitoring of environment issues: monitoring of environmental pollution problems of
atmospheric sciences, water chemistry and soil chemistry and design processes that meet the specified needs
with appropriate consideration for the public health and safety, and the cultural, societal, and environmental
considerations
Third DEGREE IN BACHELOR OF SCIENCE

Year
Degree in Bachelor of Science programme aims to introduce very important aspects of modern day course
curriculum, namely, chemistry of hydrocarbons, alcohols, carbonyl compounds, carboxylic acids, phenols,
amines, heterocyclic compounds, natural products main group elements, qualitative analysis, separation
techniques and analytical techniques. It will enable the students to understand the importance of the elements
in the periodic table including their physical and chemical nature and role in the daily life and also to
understand the concept of chemistry to inter relate and interact to the other subject like mathematics, physics,
biological science etc.
 Upon completion of a degree, chemistry students are able to employ critical thinking and scientific
inquiry in the performance, design, interpretation and documentation of laboratory experiments, at a
level suitable to succeed at an entry-level position in chemical industry or a chemistry graduate
program
 Various research institutions and industry people in the pharmaceuticals, polymers, and food industry
sectors will surely value this course.
4
Subject: Chemistry Total Credits
of the
Year Sem. Theory Units Practical Units Research subject
Paper Paper Project
1 1. Molecular polarity and Weak Chemical Forces 1. Water Quality analysis Nil
2. Simple Bonding theories of Molecules 2. Estimation of Metals ions
3. Periodic properties of Atoms Quantitative 3. Estimation of acids and alkali contents
I Fundamentals of 4. Recapitulation of basics of Organic Chemistry Analysis
4. Estimation of inorganic salts and hydrated water 4+2 = 6
Chemistry 5. Mechanism of Organic Reactions
6. Stereochemistry
7. Basic Computer system (in brief)
8. Mathematical Concepts for Chemistry
1. Chemistry of Carbohydrates 1. Qualitative and quantitative analysis of Nil
2. Chemistry of Proteins Biochemical carbohydrates
3. Chemistry of Nucleic Acids (Basic Concept) Analysis 2. Qualitative and quantitative analysis of Proteins,
Bioorganic and 4. Introductory Medicinal Chemistry amino acids and Fats
II Medicinal 5. Solid state 3. Determination and identification of Nucleic Acids 4+2 = 6
Chemistry 6. Introduction to Polymer 4. Synthesis of simple drug molecules.
7. Kinetics and Mechanism of Polymerization
8. Synthetic Dyes
2 1. Chemical kinetics Nil

2. Chemical Equilibrium Physical 1. Strengths of Solution
Chemical 3. Phase Equilibrium Analysis 2. Surface tension and viscosity of pure liquids
Dynamics & 4. Kinetic theories of Gases 3. Boiling point and Transition temperature
III 4+2 = 6
Coordination 5. Liquid states 4. Phase Equilibrium
Chemistry 6. Coordination Chemistry
7. Theories of Coordination Chemistry
8. Inorganic Spectroscopy and Magnetism
1. Atomic Structure Instrumental 1. Molecular Weight Determination Nil
2. Elementary Quantum Mechanics Analysis 2. Spectrophotometry
Quantum 3. Molecular Spectroscopy 3. Spectroscopy
IV Mechanics and 4. UV-Visible Spectroscopy
4. Chromatographic Separations 4+2 = 6
Analytical 5. Infrared Spectroscopy
1
Techniques 6. H-NMR Spectroscopy
7. Introduction to Mass Spectrometry
8. Separation Techniques
1. Alkane and Cycloalkanes Qualitative 1. Inorganic Qualitative Analysis Research
2. Alkenes Analysis 2. Elemental analysis and identification of Project
V Organic 4+4+2 +3
3. Alkynes functional groups
Synthesis-A =13
4. Arenes and Aromaticity 3. Separation of organic Mixture
5. Alcohols 4. Identification of organic compounds
5
6. Phenols
7. Ethers and Epoxides
8. Organic Halides
1. Rearrangements
2. Catalysis
Rearrangements 3. Chemistry of the Main Group Elements
and Chemistry 4. Chemistry of Transition Elements
of Group 5. Chemistry of Lanthanides
Elements 6. Chemistry of Actinides
7. Metal Carbonyls
8. Bioinorganic Chemistry
1. Reagents in Organic synthesis 1. Gravimetric Analysis

2. Organometallic Compounds Analytical
2. Paper Chromatography
3. Aldehydes and Ketones Methods
4. Carboxylic acids and their Functional 3. Thin Layer Chromatography
Organic
Derivatives
Synthesis-B 4. Thermochemistry
5. Organic Synthesis via Enolates
6. Organic Compounds of Nitrogen
7. Heterocyclic Compounds
8. Natural Products Research
4+4+2 +3
VI Project
=13
1. Thermodynamics-I
2. Thermodynamics-II
3. Electrochemistry
Chemical 4. Ionic Equilibrium
Energetics and 5. Photo Chemistry
Radiochemistry 6. Colligative Properties of Solutions
7. Surface Chemistry
8. Radiochemistry
6
COURSE SUBJECT: CHEMISTRY Total
Credits of
Year Sem. Prerequisite for Elective the
Paper Title Hours per
paper For Major Subject subject
Semester
Certificate in Yes
Fundamentals of Chemistry
Bioorganic and Theory-1 Chemistry in Open to all 60 4
I 12th
Medicinal
Chemistry Practical- Quantitative Analysis Chemistry in Yes
12th Open to all 60 2
1
Bioorganic and Medicinal Passed Sem-I, Yes
Theoty-1 Chemistry Theory paper-1 Zoo/Bot./Physics/Math/Comp Sci 60 4
II
Opted Sem-II, Yes
Biochemical Analysis
Pracical-2 Theory Ppaer-1 Zoo/Bot./Physics/Math/Comp Sci. 60 2
Diploma in Yes
Chemical Chemical Dynamics & Chemistry in Zoo/Bot./Physics/Math/Comp Sci.
Dynamics and Theoty-1 Coordination Chemistry 12th 60 4
III Physics in 12th
Analytical
Techniques Opted Sem-III, Yes
Physical Analysis
Pracical-2 Theory Ppaer-1 Zoo/Bot./Physics/Math/Comp Sci. 60 2
Quantum Mechanics and Chemistry in Yes
Theoty-1 Analytical Techniques 12th Zoo/Bot./Physics/Math/Comp Sci. 60 4
IV
Instrumental Chemistry in Yes
Practical-
Analysis 12th Zoo/Bot./Physics/Math/Comp Sci. 60 2
2
Passed Sem-I, Yes 60
Theory-1 Organic Synthesis-A 4
Degree in Theory paper- Zoo/Bot./Physics/Math/Comp Sci.
Bachelor of Rearrangements and Chemistry Passed Sem-I, Yes 60
Theory-1 4
V of Group Elements Theory paper- Zoo/Bot./Physics/Math/Comp Sci.
Science
Opted Sem-V Yes 60
Practical- Qualitative analysis
Theory Ppaer-1 Zoo/Bot./Physics/Math. 2
3
&2
7
Research ……….. …………………… 45
………… 3
Project
Passed Sem-V Yes
Theory-1 Organic Synthesis-B 60 4
Theory paper-1 Zoo/Bot./Physics/Math
Chemical Energetics and Chemistry in Yes
Theory-1 Radiochemistry 12th Zoo/Bot./Physics/Math/Comp Sci. 60 4
Physics in 12th
VI
Chemistry in Yes
Practical- Analytical Methods
12th Zoo/Bot./Physics/Math/Comp Sci. 60 2
3
Research ……………………
……………… ……………… 45 3
Project
8
Certificate in Bioorganic and Medicinal Chemistry
1 I B020101T Fundamentals of Chemistry Theory 4
B020102P Quantitative Analysis Practical 2
1 II B020201T Bioorganic and Medicinal Chemistry Theory 4
B020202P Biochemical Analysis Practical 2
9
Semester-1,
Paper-1 (Theory)
Course Title: Fundamentals of Chemistry
Programme/Class: Certificate in Semester: First
Bioorganic and Medicinal Year: First
Chemistry
Paper-1 Theory Subject: Chemistry
Course Code:B020101T Course Title: Fundamentals of Chemistry

Course outcomes:
There is nothing more fundamental to chemistry than the chemical bond. Chemical bonding is the language of logic for
chemists. Chemical bonding enables scientists to take the 100-plus elements of the periodic table and combine them in
myriad ways to form chemical compounds and materials. Periodic trends, arising from the arrangement of the periodic
table, provide chemists with an invaluable tool to quickly predict an element's properties. These trends exist because of
the similar atomic structure of the elements within their respective group families or periods, and because of the periodic
nature of the elements. Reaction mechanism gives the fundamental knowledge of carrying out an organic reaction in a
step-by-step manner. This course will provide a broad foundation in chemistry that stresses scientific reasoning and
analytical problem solving with a molecular perspective. Students will gain an understanding of
 Molecular geometries , physical and chemical properties of the molecules.
 Current bonding models for simple inorganic and organic molecules in order to predict structures and important
bonding parameters.
 The chapter Recapitulation of basics of organic chemistry gives the most primary and utmost important
knowledge and concepts of organic Chemistry.
 This course gives a broader theoretical picture in multiple stages in an overall chemical reaction. It describes
reactive intermediates , transition states and states of all the bonds broken and formed .It enables to understand
the reactants, catalyst , steriochemistry and major and minor products of any organic reaction.
 It describes the types of reactions and the Kinetic and thermodynamic aspects one should know for carrying out
any reaction and the ways how the reaction mechanism can be determined.
 The chapters Steriochemistry gives the clear picture of two-dimensional and three-dimensional structure of the
molecules, and their role in reaction mechanism.
Credits: 4 Compulsory
Max. Marks: 25+75 Min. Passing Marks:…………
Total No. of Lectures = 60
Unit Topics No. of

Lectures
Introduction to Indian ancient Chemistry and contribution of Indian Chemists, in context to the
I holistic development of modern science and technology, should be included under Continues 10
Evaluation (CIE)
10
Molecular polarity and Weak Chemical Forces :
Resonance and resonance energy, formal charge, Van der Waals forces, ion-dipole forces, dipole-
dipole interactions, induced dipole interaction, dipole moment and molecular Structure (Diatomic
and polyatomic molecules), Percentage ionic character from dipole moment, polarizing power and
polarizability. Fajan’s rules and consequences of polarization. Hydrogen bonding, van der Waals
forces, ion-dipole forces, dipole-dipole interactions, induced dipole interaction.
Simple Bonding theories of Molecules
Atomic orbitals, Aufbau principle, multiple bonding (σ and π bond approach) and bond lengths, the
valence bond theory (VBT), Concept of hybridization, hybrid orbitals and molecular geometry,
Bent’s rule, Valence shell electron pair repulsion theory (VSEPR), shapes of the following simple
II 10
molecules and ions containing lone pairs and bond pairs of electrons: H2O, NH3, PCl5, SF6, SF4,
ClF3, I3-, and H3O+. Molecular orbital theory (MOT). Molecular orbital diagrams bond orders of
homonuclear and heteronuclear diatomic molecules and ions (N2, O2, C2, B2, F2, CO, NO, and their
ions)
Periodic properties of Atoms (with reference to s & p-block):
Brief discussion, factors affecting and variation trends of following properties in groups and periods.
III Effective nuclear charge, shielding or screening effect, Slater rules, Atomic and ionic radii, 05
Electronegativity, Pauling’s/ Allred Rochow’s scales, Ionization enthalpy, Electron gain enthalpy.
Recapitulation of basics of Organic Chemistry: Hybridization, bond lengths and bond angles,
bond energy, localized and delocalized chemical bonding, Van der Waals interactions, inclusion
IV compounds, Clatherates, Charge transfer complexes, hyperconjugation, Dipole moment; Electronic 05
Displacements: Inductive, electromeric, resonance mesomeric effects and their applications
Mechanism of Organic Reactions: Curved arrow notation, drawing electron movements with
allows, half-headed and double-headed arrows, homolytic and heterolytic bond fission, Types of
V reagents – electrophiles and nucleophiles, Types of organic reactions, Energy considerations. 10

Reactive intermediates – Carbocations, carbanions, free radicals, carbenes, arynes and nitrenes (with
examples).
Steriochemistry-Concept of isomerism, Types of isomerism; Optical isomerism – elements of
symmetry, molecular chirality, enantiomers, stereogenic center, optical activity, properties of
enantiomers, chiral and achiral molecules with two stereogenic centers, disasteromers, threo and
erythro diastereomers, meso compounds, resolution of enantionmer, inversion, retention and
VI 10
recemization. Relative and absolute configuration, sequence rules, D & L and R & S systems of
nomenclature. Geometric isomerism – determination of configuration of geometric isomers, E & Z
system of nomenclature, geometric isomerism in oximes and alicyclic compounds. Conformational
isomerism – conformational analysis of ethane and n-butane; conformations of cyclohexane, axial
11
and equatorial bonds, conformation of mono substituted cyclohexane derivatives, Newman
projection and Sawhorse formulae, Fischer and flying wedge formulae, Difference between
configuration and conformation.
Basic Computer system (in brief)-Hardware and Software; Input devices, Storage devices, Output
devices, Central Processing Unit (Control Unit and Arithmetic Logic Unit); Number system (Binary,
Octal and Hexadecimal Operating System); Computer Codes (BCD and ASCII); Numeric/String
VII constants and variables. Operating Systems (DOS, WINDOWS, and Linux); Introduction of 05
Software languages: Low level and High Level languages (Machine language, Assembly language;
QBASIC, FORTRAN) Software Products (Office, chemsketch, scilab, matlab, hyperchem, etc.),
internet application.
Mathematical Concepts for Chemistry
Logarithmic relations, curve sketching, linear graphs and calculation of slopes, differentiation of
functions like Kx, ex, Xn , sin x, log x; maxima and minima, partial differentiation and reciprocity
VIII 05
relations, Integration of some useful/relevant functions; permutations and combinations,
Factorials, Probability. Numericals based on Chemical Reactions.
Suggested Readings:
1. Lee, J.D. Concise Inorganic Chemistry, Pearson Education 2010
2. Huheey, J.E., Keiter, E.A., Keiter, R. L., Medhi, O.K. Inorganic Chemistry, Principles of Structure and
Reactivity, Pearson Education 2006.
3. Douglas, B.E. and Mc Daniel, D.H., Concepts & Models of Inorganic Chemistry, Oxford, 1970
4. Shriver, D.D. & P. Atkins, Inorganic Chemistry 2nd Ed., Oxford University Press, 1994.
5. Day, M.C. and Selbin, J. Theoretical Inorganic Chemistry, ACS Publications 1962.
6. Singh J.,Yadav L.D.S.,Advanced Organic Chemistry,Pragati Edition
7. Morrison, R. N. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).
8. Carey, F. A., Guiliano, R. M.Organic Chemistry, Eighth edition, McGraw Hill Education, 2012.
9. Loudon, G. M. Organic Chemistry, Fourth edition, Oxford University Press, 2008.
10. Clayden, J., Greeves, N. &Warren, S. Organic Chemistry, 2 edition, Oxford University Press, 2012.
nd
11. Graham Solomons, T.W., Fryhle, C. B. Organic Chemistry, John Wiley & Sons, Inc.
12. Sykes, P. A guidebook to Mechanism in Organic Chemistry, Pearson Education, 2003
13. Francis, P. G. Mathematics for Chemists, Springer, 1984
Note: For the promotion of Hindi language, course books published in Hindi may be prescribed by the University
Suggested online links:
http://heecontent.upsdc.gov.in/Home.aspx
https://nptel.ac.in/courses/104/106/104106096/
https://www2.chemistry.msu.edu/faculty/reusch/VirtTxtJml/intro1.htm
https://nptel.ac.in/courses/104/103/104103071/#
This course is compulsory for the students of following subjects: Chemistry in 12 th Class
12
Suggested Continuous Evaluation Methods: Students can be evaluated on the basis of score obtained in a
mid-term exam, together with the performance of other activities which can include short exams, in-class or
on-line tests, home assignments, group discussions or oral presentations, among others .
Or
Assessment and presentation of Assignment (10 marks)

04 tests (Objective): Max marks of each test = 10 (10 marks)
(average of all 04 tests)
Overall performance throughout the semester, Discipline, (05 marks)

participation in different activities)
Course prerequisites: To study this course, a student must have had the chemistry in class 12 th
Suggested equivalent online courses:

………………………………………………………………………………………………..
Further Suggestions:
………………………………………………………………………………………………..
13
Semester-I, Paper-2 (Practical)
Course Title: Quantitative Analysis
Programme: Certificate in
Year: First Semester: I
Bioorganic and Medicinal
Chemistry
Practical paper-2 Subject: Chemistry
Course Title: Quantitative Analysis
Course Code: B020102P
Course outcomes:
Upon completion of this course the students will have the knowledge and skills to: understand the laboratory methods
and tests related to estimation of metals ions and estimation of acids and alkali contents in commercial products.
 Potability tests of water samples.
 Estimation of metal ions in samples
 Estimation of alkali and acid contents in samples
 Estimation of inorganic salts and hydrated water in samples
Credits: 2 Elective
Max. Marks: 25+75 = 100 Min. Passing Marks:
Practical 60 h
No of
Unit Topics
Lectures
Water Quality analysis
1. Estimation of hardness of water by EDTA.
I 2. Determination of chemical oxygen demand (COD). 16
3. Determination of Biological oxygen demand (BOD).

Estimation of Metals ions
1. Estimation of ferrous and ferric by dichromate method.
II 14
2. Estimation of copper using thiosulphate.
Estimation of acids and alkali contents
1. Determination of acetic acid in commercial vinegar using NaOH.
II 2. Determination of alkali content – antacid tablet using HCl. 14
3. Estimation of oxalic acid by titrating it with KMnO4.

Estimation of inorganic salts and hydrated water
1. Estimation of sodium carbonate and sodium hydrogen carbonate present in a
mixture.
IV 2. Estimation of calcium content in chalk as calcium oxalate by permanganometry. 16
3. Estimation of water of crystallization in Mohr’s salt by titrating with KMnO4.
14
Suggested Readings:
1. Mendham, J. Vogel’s Quantitative Chemical Analysis, Pearson, 2009.
2. Harris, D. C. Quantitative Chemical Analysis. 6th Ed., Freeman (2007) Chapters 3-5.
3. Harris, D.C.Exploring Chemical Analysis, 9th Ed. New York, W.H. Freeman, 2016.
4. Khopkar, S.M. Basic Concepts of Analytical Chemistry. New Age International Publisher, 2009.
5. Skoog, D.A. Holler F.J. and Nieman, T.A. Principles of Instrumental Analysis, Cengage Learning
India Edition
Note: For the promotion of Hindi language, course books published in Hindi may be prescribed by the
University
Suggestive digital platforms web links
6. https://www.labster.com/chemistry-virtual-labs/
7. https://www.vlab.co.in/broad-area-chemical-sciences
8. http://chemcollective.org/vlabs
This course can be opted as an elective by the students of following subjects: Chemistry in 12 th Class
Suggested Continuous Evaluation Methods:

Viva voce (10 marks)
Mock test (10 marks)
Overall performance (05marks)
Course prerequisites: To study this course, a student must have had the chemistry in 12th Class

………………………………………………………………………………………………..
………………………………………………………………………………………………..
15
Semester-II Paper-1
Course Title: Bioorganic and Materials Chemistry
Programme: Certificate in Semester: II
Bioorganic and Medicinal Year: 1
Chemistry
Paper-1 Elective Subject: Chemistry
Course Code: B020201T Course Title: Bioorganic and Medicinal Chemistry

Course outcomes: Biomolecules are important for the functioning of living organisms. These molecules perform
or trigger important biochemical reactions in living organisms. When studying biomolecules, one can understand
the physiological function that regulates the proper growth and development of a human body. This course aims
to introduce the students with basic experimental understanding of carbohydrates, amino acids, proteins, nucleic acids
and medicinal chemistry. Upon completion of this course students may get job opportunities in food, beverage and
pharmaceutical industries.
Credits: 4 Elective
Max. Marks: 25+75 Min. Passing Marks:………
Unit Topics No. of

Lectures
Chemistry of Carbohydrates : Classification of carbohydrates, reducing and non-reducing
sugars, General Properties of Glucose and Fructose, their open chain structure. Epimers,
mutarotation and anomers. Mechanism of mutarotation Determination of configuration of
Glucose (Fischer’s proof). Cyclic structure of glucose. Haworth projections. Cyclic structure
I of fructose. Inter conversions of sugars (ascending and descending of sugar series, conversion
10
of aldoses to ketoses). Lobry de Bruyn-van Ekenstein rearrangement; stepping–up (Kiliani-
Fischer method) and stepping–down (Ruff’s &Wohl’s methods) of aldoses; end-group-
interchange of aldoses Linkage between monosachharides, structure of disacharrides (sucrose,
maltose, lactose.)
Chemistry of Proteins: Classification of amino acids, zwitter ion structure and Isoelectric
point. Overview of primary, secondary, tertiary and quaternary structure of proteins.
Determination of primary structure of peptides, determination of N-terminal amino acid (by
DNFB and Edman method) and C–terminal amino acid (by thiohydantoin and with
II 10
carboxypeptidase enzyme). Synthesis of simple peptides (upto dipeptides) by N-protection &
C-activating groups and Merrifield solid phase synthesis. Protein denaturation/ renaturation
Mechanism of enzyme action, factors affecting enzyme action, Coenzymes and cofactors and
their role in biological reactions).
Chemistry of Nucleic Acids: Constituents of Nucleic acids: Adenine, guanine, thymine and
III 05
Cytosine (Structure only), Nucleosides and nucleotides (nomenclature), Synthesis of nucleic
16
acids, Structure of polynucleotides; Structure of DNA (Watson-Crick model) and RNA (types
of RNA), Genetic Code, Biological roles of DNA and RNA: Replication, Transcription and
Translation
Introductory Medicinal Chemistry : Drug discovery, design and development; Basic
Retrosynthetic approach. Drug action-receptor theory. Structure –activity relationships of drug
molecules, binding role of –OH group,-NH2 group, double bond and aromatic ring.
Mechanism of action of the representative drugs of the following classes: analgesics agents,
IV 10
antipyretic agents, anti-inflammatory agents (Aspirin, paracetamol); antibiotics
(Chloramphenicol); antibacterial and antifungal agents (Sulphonamides; Sulphanethoxazol,
Sulphacetamide); antiviral agents (Acyclovir), Central Nervous System agents (Phenobarbital,
Diazepam),Cardiovascular (Glyceryl trinitrate), HIV-AIDS related drugs (AZT- Zidovudine
Solid State
Definition of space lattice, unit cell. Laws of crystallography – (i) Law of constancy of
V interfacial angles, (ii) Law of rationality of indices and iii) Symmetry elements in crystals and 05
law of symmetry .X-ray diffraction by crystals. Derivation of Bragg equation. Determination
of crystal structure of NaCl, KCl and CsCl (powder method).
Introduction to Polymer
Monomers, Oligomers, Polymers and their characteristics, Classification of polymers :
Natural synthetic, linear, cross linked and network; plastics, elastomers, fibres,
Homopolymers and Co-polymers, Bonding in polymers : Primary and secondary bond forces
in polymers ; cohesive energy, and decomposition of polymers. Determination of Molecular
VI 10
mass of polymers: Number Average molecular mass (Mn) and Weight average molecular mass
(Mw) of polymers and determination by (i) Viscosity (ii) Light scattering method (iii) Gel
permeation chromatography (iv) Osmometry and Ultracentrifuging.
Silicones and Phosphazenes –Silicones and phosphazenes as examples of inorganic
polymers, nature of bonding in triphosphazenes.
Kinetics and Mechanism of Polymerization
Polymerization techniques, Mechanism and kinetics of copolymerization,Addition or chain-
growth polymerization, Free radical vinyl polymerization, ionic vinyl polymerization, Ziegler-
VII 05
Natta polymerization and vinyl polymers, Condensation or step growth-polymerization,
Polyesters, polyamides, phenol formaldehyde resins, urea formaldehyde resins, epoxy resins
and polyurethanes.
Synthetic Dyes: Colour and constitution (electronic Concept), Classification of dyes,
VIII Chemistry and synthesis of Methyl orange, Congo red, Malachite green, crystal violet, 05
phenolphthalein, fluorescein, Alizarin and Indigo.
17
Suggested Readings:
1. Davis, B. G., Fairbanks, A. J., Carbohydrate Chemistry, Oxford Chemistry Primer, Oxford University Press.
2. Finar, I. L. Organic Chemistry (Volume 2), Dorling Kindersley (India) Pvt. Ltd.(Pearson Education).
3. Nelson, D. L. & Cox, M. M. Lehninger’s Principles of Biochemistry 7th Ed., W. H. Freeman.
4. Berg, J. M., Tymoczko, J. L. & Stryer, L. Biochemistry 7th Ed., W. H. Freeman.
5. Morrison, R. T. & Boyd, R. N. Organic Chemistry, Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).
6. Patrick, G. L. Introduction to Medicinal Chemistry, Oxford University Press, UK, 2013.
7. Singh, H. & Kapoor, V.K. Medicinal and Pharmaceutical Chemistry, Vallabh Prakashan, Pitampura, New Delhi,
2012.
8. Atkins, P. W. & Paula, J. de Atkin’s Physical Chemistry Ed., Oxford University Press 13 (2006).
9. Ball, D. W. Physical Chemistry Thomson Press, India (2007).
10. Castellan, G. W. Physical Chemistry 4th Ed. Narosa (2004).
11. R.B. Seymour & C.E. Carraher: Polymer Chemistry: An Introduction, Marcel Dekker, Inc. New York,
1981.
12. G. Odian: Principles of Polymerization, 4th Ed. Wiley, 2004.
13. F.W. Billmeyer: Textbook of Polymer Science, 2nd Ed. Wiley Interscience, 1971.
14. P. Ghosh: Polymer Science & Technology, Tata McGraw-Hill Education, 1991

04 Unit tests (Objective): Max marks of each unit test = (10 marks)
10 (average of all 04 unit tests)
Overall performance throughout the semester (05 marks)

(Discipline, participation in different activities)
Course prerequisites: To study this course, a student must have Passed Sem-I, Theory paper-1
………………………………………………………………………………………………..
………………………………………………………………………………………………..
18
Semester-II , Paper-2 (Practical)
Course Title: Biochemical Analysis
Programme: Certificate in Semester: II

Bioorganic and Medicinal Year: 1
Chemistry
Subject: Chemistry
Course Title: Biochemical Analysis
Course outcomes:
This course will provide basic qualitative and quantitative experimental knowledge of biomolecules such as
carbohydrates, proteins, amino acids, nucleic acids drug molecules. Upon successful completion of this course
students may get job opportunities in food, beverage and pharmaceutical industries.
Credits: 2 Elective
Max. Marks: 25+75 = 100 Min. Passing Marks:
Practical 60-h
No of
Unit Topics
Lectures
Qualitative and quantitative analysis of Carbohydrates: .
1. Separation of a mixture of two sugars by ascending paper chromatography
I 2. Differentiate between a reducing/ nonreducing sugar 15
3. Synthesis of Osazones.
Qualitative and quantitative analysis of Proteins, amino acids and Fats

1. Isolation of protein.
2. Determination of protein by the Biuret reaction.
3. TLC separation of a mixture containing 2/3 amino acids
4. Paper chromatographic separation of a mixture containing 2/3 amino acids
II 20
5. Action of salivary amylase on starch
6. To determine the concentration of glycine solution by formylation method.
7. To determine the saponification value of an oil/fat.
8. To determine the iodine value of an oil/fat
Determination and identification of Nucleic Acids

1. Determination of nucleic acids
III 12
2. Extraction of DNA from onion/cauliflower
Synthesis of Simple drug molecules

1. To synthesize aspirin by acetylation of salicylic acid and compare it with the
ingredient of an aspirin tablet by TLC.
IV 13
2. Synthesis of barbituric acid
3. Synthesis of propranolol
19
Suggested Readings:
1. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.G.; Tatchell, A.R. Practical Organic Chemistry, 5th Ed., Pearson
(2012).
2. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry, Pearson Education.
3. Vogel’s Qualitative Inorganic Analysis, Revised by G. Svehla.
4. Vogel, A.I. A Textbook of Quantitative Analysis, ELBS. 1986
5. Furniss, B.S.; Hannaford, A.J.; Rogers, V.; Smith, P.W.G.; Tatchell, A.R. Vogel’s Textbook of Practical
Organic Chemistry, ELBS.
6. Ahluwalia, V.K. & Aggarwal, R. Comprehensive Practical Organic Chemistry,Universities Pres
7. Cooper, T.G. Tool of Biochemistry. Wiley-Blackwell (1977).
8. Wilson, K. & Walker, J. Practical Biochemistry. Cambridge University Press (2009).
9. Varley, H., Gowenlock, A.H & Bell, M.: Practical Clinical Biochemistry, Heinemann,

Course prerequisites: To study this course, a student must have Opted Sem-II, Theory Ppaer-1.
………………………………………………………………………………………………..
………………………………………………………………………………………………..
20
Diploma in Chemical Dynamics and Analytical Techniques
2 III B020301T Chemical Dynamics & Coordination Theory 4

Chemistry
B020302P Physical Analysis Practical 2
IV B020401T Quantum Mechanics and Analytical Theory 4

Techniques
B020402P Instrumental Analysis Practical 2
21
Semester III, Paper-1 (Theory)
Course Title: Chemical Dynamics & Coordination Chemistry
Programme: Diploma in Chemical Semester: III
Year: Two
Dynamics and Analytical Techniques
Paper-1 Theory Subject: Chemistry
Course Code:B020301T Course Title: Chemical Dynamics & Coordination Chemistry

Course outcomes: Upon successful completion of this course students should be able to describe the characteristic of
the three states of matter and describe the different physical properties of each state of matter. kinetic theory of gases, laws
of crystallography , liquid state and liquid crystals, conductometric, potentiometric, optical methods, polarimetry and
spectrophotometer technique to study Chemical kinetics and chemical equilibrium. After the completion of the course,
Students will be able to understand .metal- ligand bonding in transition metal complexes, thermodynamic and kinetic
aspects of metal complexes.
Credits: 4 Elective
Max. Marks: 25+75 Min. Passing Marks:…………
Unit Topics No. of

Lectures
Chemical Kinetics: Rate of a reaction, molecularity and order of reaction, concentration dependence
of rates, mathematical characteristic of simple chemical reactions – zero order, first order, second
order, pseudo order, half-life and mean life. Determination of the order of reaction – differential
method, method of integration, half-life method and isolation method.
I 10
Theories of chemical kinetics: Effect of temperature on rate of reaction, Arrhenius equation,
concept of activation energy. Simple collision theory based on hard sphere model, transition state
theory (equilibrium hypothesis). Expression for the rate constant based on equilibrium constant and
thermodynamic aspects (no derivation ).
Chemical Equilibrium : Equilibrium constant and free energy, thermodynamic derivation of law
II of mass action. Le-Chatelier's principle. reaction isotherm and reaction isochore – Clapeyron- 5
Clausius equation and its applications.
Phase Equilibrium : Statement and meaning of the terms-phase, component and degree of freedom,
derivation of Gibbs phase rule, phase equilibria of one component system– water, CO2 and systems.
III 05
Phase equilibria of two component systems – Solid - liquid equilibria , simple eutectic – Bi-Cd, Pb-
Ag systems.
22
Kinetic theories of gases
Gaseous State: Postulates of kinetic theory of gases, deviation from ideal behavior, van der Waals
equation of state.
Critical phenomena: PV isotherms of real gases, continuity of states, the isotherms of Van der
Waals equation, relationship between critical constants and Van der Waals constants, the law of
IV 10
corresponding states, reduced equation of state.
Molecular Velocities: Qualitative discussion of the Maxwell's distribution of molecular velocities,
collision number, mean free path and collision diameter.
Liquid State
Liquid State: Intermolecular forces, structure of liquids (a qualitative description). Structural
V differences between solids, liquids and gases. Liquid crystals: Difference between liquid crystal, 5
solid and liquid. Classification, structure of nematic and cholesterol phases.
Liquids in solids (gels): Classification, preparation and properties, inhibition, general application
Coordination Chemistry
Werner’s theory of coordination complexes, classification of ligands, ambidentate ligands, chelates,
VI coordination numbers, IUPAC nomenclature of coordination complexes (up to two metal centers), 5
Isomerism in coordination compounds, constitutional and stereo isomerism, geometrical and optical
isomerism in square planar and octahedral complexes.
Theories of Coordination Chemistry
I Metal- ligand bonding in transition metal complexes, limitations of valance bond theory, an
elementary idea of crystal field theory, crystal field splitting in octahedral, tetrahedral and square
planner complexes, John teller effect, factors affecting the crystal-field parameters.
VII 10
II. Thermodynamic and kinetic aspects of metal complexes: A brief outline of thermodynamic
stability of metal complexes and factors affecting the stability, stability constants of complexes and
their determination, substitution reactions of square planar complexes
Inorganic Spectroscopy and Magnetism

I)Electronic spectra of Transition Metal Complexes
Types of electronic transitions, selection rules for d-d transitions, spectroscopic ground states,
spectrochemical series, Orgel-energy level diagram for d1 and d9 states, discussion of the electronic
VIII 10
spectrum of [Ti(H2O)6]3+ complex ion.
II)Magnetic properties of transition metal complexes, types of magnetic behaviour, methods of
determining magnetic susceptibility, spin-only formula, L-S coupling, correlation of µ s and µ eff
23
values, orbital contribution to magnetic moments, application of magnetic moment data for 3d-metal
complexes.
Suggested Readings:
3. Castellan, G. W. Physical Chemistry 4th Ed. Narosa (2004).
4. Cotton,F.A, Wilkinson,G and Gaus,P. L ,Basic Inorganic Chemistry,3rd Edition ,Wiley 1995
5. Lee,J.D, Concise Inorganic Chemistry 4th Edition ELBS,1977
6. Douglas,B, McDaniel ,D and Alexander,J ,Concepts of Models of Inorganic Chemistry, John Wiley & Sons;
3rd edition , 1994
7. Shriver,D.E Atkins,P.W and Langford,C .H , Inorganic Chemistry ,Oxford University Press, 1994.
8. Porterfield ,W.W, Inorganic Chemistry ,Addison Wesley 1984.
9. Sharpe,A .G, Inorganic Chemistry, ELBS,3RD edition ,1993
10. Miessler,G.L,Tarr,D.A, Inorganic Chemistry, 2nd edition , Prentice Hall,2001
Suggestive digital platforms web links-
Suggestive digital platforms web links:
11. https://swayam.gov.in/
12. https://www.coursera.org/learn/physical-chemistry
13. https://www.mooc-list.com/tags/physical-chemistry
14. https://www.openlearning.com/courses/introduction-to-physical-chemistry/
15. https://www.my-mooc.com/en/categorie/chemistry
16. https://onlinecourses.swayam2.ac.in/nce19_sc15/preview
17. https://swayam.gov.in/
18. https://www.coursera.org/browse/physical-science-and-engineering/chemistry
Or
04 Unit tests (Objective): Max marks of each unit test = 10 (10 marks)
(average of all 04 unit tests)
Overall performance throughout the semester ( Discipline, (05 marks)

Course prerequisites: To study this course, a student must have had the chemistry in class 12 th , Physics in
Class 12th

………………………………………………………………………………………………..
………………………………………………………………………………………………..
24
25
Semester III, Paper-2 (Practical):
Course Title: Physical Analysis
Programme: Diploma in Semester: III

Year: Two
Chemical Dynamics and
Analytical Techniques
Course Title: Physical Analysis
Course Outcomes: Upon successful completion of this course students should be able to calibrate apparatus and prepare
solutions of various concentrations, estimation of components through volumetric analysis; to perform dilatometric
experiments: one and two component phase equilibrium experiments.
Credits: 4 Elective
Max. Marks: 25 +75 Min. Passing Marks:
Practical 60 h
No of
Unit Topics
Lectures
Strengths of Solution
Calibration of fractional weights, pipettes and burettes. Preparation of standards solutions. Dilution –
0.1 M to 0.001 M solutions.
Mole Concept and Concentration Units :Mole Concept, molecular weight, formula weight, and
I 20
equivalent weight. Concentration units: Molarity, Formality, Normality, Molality, Mole fraction,
Percent by weight, Percent by volume, Parts per thousand, Parts per million, Parts per billion, pH,
pOH, milli equivalents, Milli moles
Surface Tension and Viscosity

II 1. Determination of surface tension of pure liquid or solution 06
2. Determination of viscosity of liquid pure liquid or solution
Boiling point and Transition Temperature
1. Boiling point of common organic liquid compounds ANY FIVE ]nbutylalcohol, cyclohexanol,
ethyl methyl ketone, cyclohexanone, acetylacetone, isobutyl methyl ketone, isobutyl alcohol,
acetonitrile, benzaldehyde and acetophenone. [Boiling points of the chosen organic compounds
III 14
should preferably be within 1800C].
2. Transition Temperature, Determination of the transition temperature of the given substance by
thermometric /dialometric method (e.g. MnCl2.4H2O/SrBr2.2H2O )
Phase Equilibrium
IV 20
26
1. To study the effect of a solute (e.g. NaCl, succinic acid) on the critical solution temperature of
two partially miscible liquids (e.g. phenolwater system) and to determine the concentration of
that solute in the given phenol-water system
2. To construct the phase diagram of two component (e.g. diphenylamine – benzophenone) system
by cooling curve method.
Suggested Readings:
1. Skoog .D.A., West.D.M and Holler .F.J., “Analytical Chemistry: An Introduction”, 7th edition, Saunders college
publishing, Philadelphia,(2010).
2. Larry Hargis.G” Analytical Chemistry: Principles and Techniques” Pearson©(1988 )

Course prerequisites: To study this course, a student must have Opted Sem-III, Theory Ppaer-1

………………………………………………………………………………………………..
………………………………………………………………………………………………..
27
Semester IV Paper-1 (Theory)
Course Title: Quantum Mechanics and Analytical Techniques
Programme: Diploma in Semester: IV
Chemical Dynamics and Year: Two
Paper-1 Elective Subject: Chemistry
Course Code: BO20401T

Course Title: Quantum Mechanics and Analytical Techniques
Course Outcomes:: Upon successful completion of this course students should be able to describe atomic structure,
elementary quantum mechanics ,wave function and its significance ;Schrodinger wave equation and its applications;
Molecular orbital theory, basic ideas – Criteria for forming molecular orbital from atomic orbitals , Molecular
Spectroscopy, Rotational Spectrum ,vibrational Electronic Spectrum: photo chemistry and kinetics of photo chemical
reaction
Analytical chemistry plays an enormous role in our society, such as in drug manufacturing, process control in industry,
environmental monitoring, medical diagnostics, food production, and forensic surveys. It is also of great importance in
different research areas. Analytical chemistry is a science that is directed towards creating new knowledge so that
chemical analysis can be improved to respond to increasing or new demands.
 Students will be able to explore new areas of research in both chemistry and allied fields of science and technology.
 Students will be able to function as a member of an interdisciplinary problem solving team.
 Students will be skilled in problem solving, critical thinking and analytical reasoning as applied to scientific
problems
 Students will gain an understanding of how to determine the structure of organic molecules using IR and NMR
spectroscopic techniques
 To develop basic skills required for purification, solvent extraction, TLC and column chromatography
Credits: 4 Elective
Max. Marks: 25+75 Min. Passing Marks:……………
Total No. of Lectures- = 60
Unit Topics No. of

Lectures
Atomic Structure: Idea of de-Broglie matter waves, Heisenberg uncertainty principle, atomic
orbitals, Schrödinger wave equation, significance of Ψ and Ψ 2 , quantum numbers, radial and
I angular wave functions and probability distribution curves, shapes of s, p, d, orbitals. Aufbau 5
and Pauli exclusion principles, Hund's multiplicity rule.
Elementary Quantum Mechanics : Black-body radiation, Planck's radiation law, photoelectric
II effect, heat capacity of solids, Bohr's model of hydrogen atom (no derivation) and its defects, 10
Compton effect. de-Broglie hypothesis. Heisenberg uncertainty principle . Hamiltonian Operator.
28
Schrödinger wave equation (time dependent and time independent) and its importance, physical
interpretation of the wave function, postulates of quantum mechanics, particle in a one
dimensional box. Schrödinger wave equation for H-atom, separation into three equations (without
derivation), quantum numbers and their importance, hydrogen like wave functions, radial wave
functions, angular wave functions. Molecular orbital theory, basic ideas – Criteria for forming
MO from AO, construction of MO by LCAO – H2 + ion, calculation of energy levels from wave
functions, physical picture of bonding and anti-bonding wave functions, concept of σ, σ*, π, π*
orbitals and their characteristics.
Molecular Spectroscopy: Introduction: Electromagnetic radiation, regions of the spectrum, basic

features of different spectrometers, statement of the Born-Oppenheimer approximation, degrees
of freedom
Rotational Spectrum:Diatomic molecules . Energy levels of a rigid rotor (semi-classical
principles), selection rules, spectral intensity, distribution using population distribution (Maxwell-
Boltzmann distribution) determination of bond length, qualitative description of non-rigid rotor,
isotope effect .
III 10
Vibrational Spectrum: Infrared spectrum : Energy levels of simple harmonic oscillator,
selection rules, pure vibrational spectrum, intensity, determination of force constant and
qualitative relation of force constant and bond energies, effect of anharmonic motion and isotope
on the spectrum, idea of vibrational frequencies of different functional groups.
Raman spectrum: Concept of polarizability , pure rotational and pure vibrational, Raman
spectra of diatomic molecules, selection rules. Electronic Spectrum: Concept of potential energy
curves for bonding and antibonding molecular orbitals, qualitative description of selection rules.
UV-Visible Spectroscopy :
Origin of spectra, interaction of radiation with matter, fundamental laws of spectroscopy and
selection rules. Types of electronic transitions, λmax, chromophores and auxochromes,
IV Bathochromic and Hypsochromic shifts, Intensity of absorption; application of Woodward Rules 5

for calculation of λmax for the conjugated dienes: alicyclic, homoannular and heteroannular;
extended conjugated systems distinction between cis and trans isomers (Cis and trans stilbene) .
Infrared Spectroscopy:
IR Spectroscopy: Fundamental and non-fundamental molecular vibrations; Hooke's law
selection rule, IR absorption positions of various functional groups (C=O, OH, NH, COOH and
V 5
nitile) , Effect of H-bonding, conjugation, resonance and ring size of cyclic ketones and lactones
on IR absorptions; Fingerprint region and its significance; application in functional group analysis
and and interpretation of I.R. spectra of simple organic compounds.
29
1
H-NMR Spectroscopy (PMR)
NMR Spectroscopy: introduction; nuclear spin; NMR active molecules; basic principles of Proton
Magnetic Resonance; choice of solvent and internal standard; equivalent and non-equivalent
protons; chemical shift and factors influencing it; ring current effect; significance of the terms:
up-/downfield, shielded and deshielded protons; spin coupling and coupling constant (1st order
spectra); relative intensities of first-order multiplets: Pascal’s triangle; chemical and magnetic
VI equivalence in NMR ; anisotropic effects in alkene, alkyne, aldehydes and aromatics; NMR peak 10
area, integration; relative peak positions with coupling patterns of common organic compounds;
interpretation of NMR spectra of simple compounds. Applications of IR, UV and NMR
spectroscopy for identification of simple organic molecules such as Ethanol, Ethyl acetate,
acetone, acetaldehyde, dimethylformamide, Cis and trans 1,2-dimethyl cycloprpanone, propene
, vinyl chloride, acetophenone, benzaldehyde, phenol, Toluene and ethyl benzene.
Introduction to Mass Spectrometry: Principle of mass spectrometry, the mass spectrum, mass
VII spectrometry diagram, molecular ion, metastable ion, fragmentation process, McLafferty 3
rearrangement.
Separation Techniques: Solvent extraction: Classification, principle and efficiency of the
technique. Mechanism of extraction: extraction by solvation and chelation. Technique of
extraction: batch, continuous and counter current extractions. Qualitative and quantitative aspects
of solvent extraction: extraction of metal ions from aqueous solution, extraction of organic species
VIII 07
from the aqueous and non-aqueous media.
Chromatography: Classification, principle and efficiency of the technique. Mechanism of
separation: adsorption, partition & ion exchange. Development of chromatograms: frontal, elution
and displacement methods.
Suggested Readings:
1. Alberty,R A, Physical Chemistry,4 th editionWiley Eastern Ltd ,2001.

2. Atkins,P W,the elements of physical chemistry,Oxford ,1991
3. Barrow,G .M,International student Edition .McGraw Hill, McGraw-Hill,1973.
4. Cotton,F.A, Wilkinson,G and Gaus,P. L ,Basic Inorganic Chemistry,3rd Edition ,Wiley 1995
5. Lee,J.D, Concise Inorganic Chemistry 4th Edition ELBS,1977
6. Clayden, J., Greeves, N., Warren, S., Organic Chemistry, Second edition, Oxford University Press 2012.
7. Silverstein, R. M., Bassler, G. C., Morrill, T. C. Spectrometric Identification of Organic Compounds, John
Wiley and Sons, INC, Fifth edition.
8. Pavia, D. L. et al. Introduction to Spectroscopy, 5th Ed. Cengage Learning India Ed.
9. Willard, H.H. et al.: Instrumental Methods of Analysis, 7th Ed. Wardsworth Publishing Company, Belmont,
California, USA, 1988.
10. Christian, G.D. Analytical Chemistry, 6th Ed. John Wiley & Sons, New York, 2004.
11. Harris, D.C.: Exploring Chemical Analysis, 9th Ed. New York, W.H. Freeman, 2016.

30
1. https://www.coursera.org/courses?query=chemistry&languages=en
2. https://www.mooc-list.com/tags/physical-chemistry
3. https://www.coursera.org/learn/physical-chemistry
4. https://ocw.mit.edu/courses/chemistry/5-61-physical-chemistry-fall-2017/
5. http://heecontent.upsdc.gov.in/Home.aspx
6. https://nptel.ac.in/courses/104/108/104108078/
Or
Overall performance throughout the semester (Discipline, (05 marks)

Course prerequisites: To study this course, a student must have had the chemistry in class 12 th

………………………………………………………………………………………………..
………………………………………………………………………………………………..
31
Semester IV, Paper-2 (Practical)
Course Title: Instrumental Analysis
Programme: Diploma in Semester: V

Year: Two
Chemical Dynamics and
Course Title: Instrumental Analysis
Course outcomes: Upon completion of this course, chemistry majors are able to employ critical thinking and
scientific inquiry in the performance, design, interpretation and documentation of laboratory experiments, at a
level suitable to succeed at an entry-level position in chemical industry or a chemistry graduate program.
 Students will be able to explore new areas of research in both chemistry and allied fields of science and
technology.
 Students will be able to function as a member of an interdisciplinary problem solving team.
 Students will be skilled in problem solving, critical thinking and analytical reasoning as applied to scientific
problems
 Students will gain an understanding of how to determine the structure of organic molecules using IR and
NMR spectroscopic techniques
 To develop basic skills required for purification, solvent extraction, TLC and column chromatography
Credits: 2 Elective
Max. Marks: 25 + 75 Min. Passing Marks:
Practical 60 h
Unit Topics No
of Lectures
Molecular Weight Determination
1. Determination of molecular weight of a non-volatile solute by Rast method/ Beckmann
freezing point method.
I 2. Determination of the apparent degree of dissociation of an electrolyte (e.g., NaCl) in
10
aqueous solution at different concentrations by ebullioscopy
Spectrophotometry
1. To verify Beer – Lambert Law for KMnO4/K2Cr2O7 and determining the concentration
II of the given solution of the substance from absorption measurement 20

2. Determination of pKa values of indicator using spectrophotometry.
3. Determination of chemical oxygen demand (COD).
32
4. Determination of Biological oxygen demand (BOD).
Spectroscopy
1. Assignment of labelled peaks in the IR spectrum of the same compound explaining the
relative frequencies of the absorptions (C-H, O-H, N-H, C-O, C-N, C-X, C=C, C=O,
N=O, C≡C, C≡N stretching frequencies; characteristic bending vibrations are included.
III Spectra to be provided). 10

1
2. Assignment of labelled peaks in the H NMR spectra of the known organic compounds
explaining the relative δ-values and splitting pattern.
3. Identification of simple organic compounds by IR spectroscopy and NMR
spectroscopy (Spectra to be provided).
Chromatographic Separations
1. Paper chromatographic separation of following metal ions: i. Ni (II) and Co (II) ii.
Cu(II) and Cd(II)
2. Separation of a mixture of o-and p-nitrophenol or o-and p-aminophenol by thin layer
IV Chromatography (TLC)
20
3. Separation and identification of the amino acids present in the given mixture by paper
chromatography. Reporting the Rf values
4. TLC separation of a mixture of dyes (fluorescein and methylene blue)
Suggested Readings:
1. Mendham, J., A. I. Vogel’s Quantitative Chemical Analysis 6th Ed., Pearson, 2009.
2. Willard, H.H. et al.: Instrumental Methods of Analysis, 7th Ed. Wardsworth Publishing Company, Belmont,
California, USA, 1988.
3. Christian, G.D. Analytical Chemistry, 6th Ed. John Wiley & Sons, New York, 2004.
4. Harris, D.C.Exploring Chemical Analysis, 9th Ed. New York, W.H. Freeman, 2016.
6. Skoog, D.A. Holler F.J. and Nieman, T.A. Principles of Instrumental Analysis, Cengage Learning India
Edition.
7. Mikes, O. & Chalmes, R.A. Laboratory Handbook of Chromatographic & AlliedMethods, Elles Harwood
Ltd. London.
8. Ditts, R.V. Analytical Chemistry: Methods of separation. Van Nostrand, New York, 1974.

33
Course prerequisites: To study this course, a student must have had the chemistry in class

………………………………………………………………………………………………..
………………………………………………………………………………………………..
34
Degree in Bachelor of Science
3 V B020501T Organic Synthesis-A Theory 4
B020502T Rearrangements and Chemistry of Group Theory 4

Elements
B020503P Qualitative Analysis Practical 2
VI B020601T Organic Synthesis-B Theory 4
B020602T Chemical Energetics and Radiochemistry Theory 4
B020603P Analytical Methods Practical 2
35
Semester V, Paper-1 (Theory)
Course Title: Organic Synthesis A
Programme: Degree in Bachelor of Semester: V
Year: Three
Science
Paper-2 Theory Compulsory Subject: Chemistry
Course Code: B020501T Course Title: Organic Synthesis A

Course outcomes: Hydrocarbons are the principal constituents of petroleum and natural gas. They serve as fuels and
lubricants as well as raw materials for the production of plastics, fibers, rubbers, solvents and industrial chemicals. This
course will provide a broad foundation in for the synthesis of hydrocarbons. Hydroxy and carbonyl compounds are
industrially important compounds The industries of plastics, fibers, petroleum and rubbers will specially recognize this
course. Students will gain an understanding of which are used as solvents and raw material for synthesis of drug and
other pharmaceutically important compounds.
 Synthesis and chemical properties of aliphatic and aromatic hydrocarbons
 Synthesis and chemical properties of alcohols, halides carbonyl compounds, carboxylic acids and esters
 How to design and synthesize aliphatic and aromatic hydrocarbons.
 How to convert aliphatic and aromatic hydrocarbons to other industrially important compounds
 Functional group interconversion.
.
Credits: 4 Elective
Max. Marks: 25+75 Min. Passing Marks:
Unit Topics No. of

Lectures
Chemistry of Alkanes and Cycloalkanes
A) Alkanes :Classification of carbon atom in alkanes, General methods of preparation, physical and
chemical properties of alkanes: Wurtz Reaction, Wurtz-Fittig Reactions, Free radical substitutions:
I Halogenation -relative reactivity and selectivity

8
B) Cycloalkanes: Nomenclature, methods of formation, chemical reactions, Baeyer's strain theory
and its limitations. Chair, Boat and Twist boat forms of cyclohexane with energy diagrams ring strain
in small rings, theory of strain less rings. The case of cyclopropane ring, banana bonds.
Chemistry of Alkenes
Methods of formation of alkenes, Addition to C=C: mechanism (with evidence wherever applicable),
reactivity, regioselectivity (Markownikoff and anti-Markownikoff additions) and stereoselectivity;
II 12
reactions: hydrogenation, halogenation, hydrohalogenation, hydration, oxymercuration
demercuration, hydroboration-oxidation, epoxidation, syn and anti-hydroxylation, ozonolysis,
addition of singlet and triplet carbenes; Simmons-Smith cyclopropanation reaction; electrophilic
36
addition to diene (conjugated dienes and allene); radical addition: HBr addition; mechanism of allylic
and benzylic bromination in competition with brominations across C=C; use of NBS; interconversion
of E- and Z- alkenes.
Chemistry of Alkynes
Methods of formation of alkynes, Addition to C≡C, mechanism, reactivity, regioselectivity and
stereoselectivity; reactions: hydrogenation, halogenations, hydrohalogenation, hydration,
III 06
oxymercuration demercuration, hydroboration-oxidation, dissolving metal reduction of alkynes
(Birch); reactions of terminal alkynes by exploring its acidity; inter conversion of terminal and non-
terminal alkynes.
Aromaticity and Chemistry of Arenes
Nomenclature of benzene derivatives, MO picture of benzene, Aromaticity: Hückel’s rule, aromatic
character of arenes, cyclic carbocations/carbanions. Electrophilic aromatic substitution:
IV 10
halogenation, nitration, sulphonation and Friedel-Craft’s alkylation/acylation with their Mechanism.
Directing effects of the groups. Birch reduction, Methods of formation and chemical reactions of
alkylbenzenes, alkynylbenzenes and biphenyl, naphthalene and anthracene.
Chemistry of Alcohols
Classification and nomenclature, Monohydric alcohols – nomenclature, methods of formation by
reduction of Aldehydes, Ketones, Carboxylic acids and Esters, Hydrogen bonding, Acidic nature,
V Reactions of alcohols. Dihydric alcohols nomenclature, methods of formation, chemical reactions 8
of vicinal glycols, oxidative cleavage [Pb(OAc)4 and HIO4] and pinacol pinacolone rearrangement.
Trihydric alcohols - nomenclature, methods of formation, chemical reactions of glycerol.
Chemistry of Phenols : Nomenclature, structure and bonding, preparation of phenols, physical

properties and acidic character, Comparative acidic strengths of alcohols and phenols, resonance
stabilization of phenoxide ion. Reactions of phenols – electrophilic aromatic substitution, acylation
VI 06
and carboxylation. Mechanisms of Fries rearrangement, Claisen rearrangement, Gatterman syntheis,
Hauben Hoesch reaction, Lederer-Manasse reaction and Reimer-Tiemann reaction
Chemistry of Ethers and Epoxides: Nomenclature of ethers and methods of their formation,
physical properties, Chemical reactions – cleavage and autoxidation, Ziesel's method. Synthesis of
VII 05
epoxides, Acid and base-catalyzed ring opening of epoxides, orientation of epoxide ring opening,
reactions of Grignard and organolithium reagents with epoxides.
Chemistry of Organic Halides
VIII Nomenclature and classes of alkyl halides, methods of formation, chemical reactions, Mechanisms 05
of nucleophilic substitution reactions of alkyl halides, SN2 and SN1 reactions with energy profile
37
diagrams; Polyhalogen compounds : Chloroform, carbon tetrachloride; Methods of formation of aryl
halides, nuclear and side chain reactions; The addition-elimination and the elimination-addition
mechanisms of nucleophilic aromatic substitution reactions; Relative reactivities of alkyl halides vs
allyl, vinyl and aryl halides, Synthesis and uses of DDT and BHC.
Suggested Readings:
2. Sykes, P. A guidebook to Mechanism in Organic Chemistry, Pearson Education, 2003.
5. Clayden, J., Greeves, N. &Warren, S. Organic Chemistry, 2nd edition, Oxford University Press, 2012.
7. Smith, J. G. Organic Chemistry, Tata McGraw-Hill Publishing Company Limited.
8. March, J. Advanced Organic Chemistry, Fourth edition, Wiley. \
9. Bariyar and Goyal , Organic Chemistry-II, Krishna Prakashan Media, Meerut , Third Eddition, 2019
This course is compulsory for the students of following subjects: Chemistry in 12 th Class

Students can be evaluated on the basis of score obtained in a mid-term exam, together with the performance
of other activities which can include short exams, in-class or on-line tests, home assignments, group
discussions or oral presentations, among others .
Or

Course prerequisites: To study this course, a student must have Passed Sem-I, Theory paper

………………………………………………………………………………………………..
………………………………………………………………………………………………..
38
Semester-V Paper-2
Course Title: Rearrangements and Chemistry of Group Elements
Programme: Degree in Bachelor of Semester: V

Year: Three
Science
Paper-2 Theory Elective Subject: Chemistry
Course Title: Rearrangements and Chemistry of Group Elements
Course Code: B020502T
Course outcomes: This paper provides detailed knowledge of synthesis of various class of organic compounds and
functional groups inter conversion. Organic synthesis is the most important branch of organic chemistry which provides
jobs in production & QC departments related to chemicals, drugs, medicines, FMCG etc. industries.
 It relates and gives an analytical aptitude for synthesizing various industrially important compounds.
 This paper also provides a detailed knowledge on the elements present in our surroundings, their
occurrence in nature. Their position in periodic table, their physical and chemical properties as well as
their extraction. This paper also gives detailed understanding of the s, p, d and f block elements and their
characteristics.
Credits: 4 Elective
Unit Topics No. of

Lectures
Rearrangements
I A detailed study of the following rearrangements: Pinacol-pinacolone, Demjanov, BenzilBensilic 6

acid, Favorskii, Hofman, Curtius, Schmidt, Baeyer-Villiger and Fries rearrangement
Catalysis
General principles and properties of catalysts, homogenous catalysis (catalytic steps and examples)
II and heterogenous catalysis (catalytic steps and examples) and their industrial applications, 8
Deactivation or regeneration of catalysts. Phase transfer catalysts, application of zeolites as
catalysts. Enzyme catalysis; Michaelis-Menten equation, turn-over number.
III Chemistry of Main Group Elements

10
39
s-Block Elements: Comparative study, diagonal relationship, salient features of hydrides, solvation
and complexation tendencies including their function in biosystems, an introduction to alkyls and
aryls.
p-Block Elements: Comparative study (including diagonal relationship) of groups 13-17 elements,
compounds like hydrides, oxides, oxyacids and halides of group 13-16, hydrides of boron-diborane
and higher boranes, borazine, borohydrides, fullerenes, carbides, fluorocarbons, silicates (structural
principle), tetrasulphur tetra nitride, basic properties of halogens, interhalogens and polyhalides.
Chemistry of Noble Gasses: Chemical properties of the noble gases, chemistry of xenon, structure
and bonding in xenon compounds.
Chemistry of Transition Elements
Chemistry of Elements of First Transition Series -Characteristic properties of d-block elements.
Binary compounds (hydrides, carbides and oxides) of the elements of the first transition series and
complexes with respect to relative stability of their oxidation states, coordination number and
IV geometry. 06
Chemistry of Elements of Second and Third Transition Series- General characteristics,
comparative treatment of Zr/Hf, Nb/Ta, Mo/W in respect of ionic radii, oxidation states, magnetic
behavior, spectral properties and stereochemistry.
Chemistry of Lanthanides
V Electronic structure, oxidation states and ionic radii and lanthanide contraction, complex formation, 4
occurrence and isolation, ceric ammonium sulphate and its analytical uses.
Chemistry of Actinides
VI Electronic configuration, oxidation states and magnetic properties, chemistry of separation of Np, 4
Pu and Am from U.
Metal Carbonyls
VII Metal carbonyls: 18-electron rule, preparation, structure and nature of bonding in the mononuclear 6
and dinuclea carbonyls.
Bioinorganic Chemistry
Essential and trace elements in biological processes, metalloporphyrins with special reference to
VIII 6
heamoglobin and myoglobin. Biological role of alkali and alkaline earth metal ions with special
reference to Ca2+ . Nitrogen fixation.
Suggested Readings:
40
8. March, J. Advanced Organic Chemistry, Fourth edition, Wiley.
9. Lee, J.D. Concise Inorganic Chemistry, Pearson Education 2010
10. Huheey, J.E., Keiter, E.A., Keiter, R. L., Medhi, O.K. Inorganic Chemistry, Principles of Structure and
Reactivity, Pearson Education 2006
11. Douglas, B.E. and Mc Daniel, D.H., Concepts & Models of Inorganic Chemistry, Oxford, 1970
12. Shriver, D.D. & P. Atkins, Inorganic Chemistry 2nd Ed., Oxford University Press, 1994.
13. Day, M.C. and Selbin, J. Theoretical Inorganic Chemistry, ACS Publications 1962.
14. Francis, P. G. Mathematics for Chemists, Springer, 1984
15. Prakash Satya,Tuli G.D.,Basu S.K.Madan R.D.,Advanced inorganic Chemistry,S.Chand publishing.
16. Bariyar and Goyal , Inorganic Chemistry-II, Krishna Prakashan Media, Meerut , Third Eddition, 2019

https://swayam.gov.in/

Or

Course prerequisites: To study this course, a student must have Passed Sem-I, Theory paper
………………………………………………………………………………………………..
………………………………………………………………………………………………..
41
Semester V, Paper-3 (Practical)
Course Title: Qualitative Analysis
Programme: Degree in Year: Three Semester: V

Bachelor of Science
Course Title: Qualitative Analysis
Course outcomes:
Upon completion of this course the students will have the knowledge and skills to: understand the laboratory methods
and tests related to inorganic mixtures and organic compounds.
 Identification of acidic and basic radicals in inorganic mixtures
 Separation of organic compounds from mixture
 Elemental analysis in organic compounds
 Identification of functional group in organic compounds
 Identification of organic compound
Credits: 2 Elective
Practical 60 h
No of
Unit Topics
lectures
Inorganic Qualitative Analysis
Semi micro Analysis – cation analysis, separation and identification of ions from Groups
I I, II, III, IV, V and VI, Anion analysis. Mixture containing 6 radicals-2 +4 or 4+ or 3+3 16
Elemental analysis and identification of functional groups

Detection of extra elements (N, S and halogens) and functional groups (phenolic,
II carboxylic, carbonyl, esters, carbohydrates, amines, amides, nitro and anilide) in simple 14
organic compounds.
Separation of Organic Mixture
Analysis of an organic mixture containing two solid components using water, NaHCO3,
III NaOH for separation and preparation of suitable derivatives 18
Identification of organic compounds

Identification of an organic compound through the functional group analysis, determination
IV 12
of melting point and preparation of suitable derivatives.
42
Suggested Readings:
1. Svehla, G. Vogel’s Qualitative Inorganic Analysis, Pearson Education, 2012.
2. Mendham, J. Vogel’s Quantitative Chemical Analysis, Pearson, 2009.
3. Vogel, A.I., Tatchell, A.R., Furnis, B.S., Hannaford, A.J. & Smith, P.W.G., Textbook of Practical
Organic Chemistry, Prentice-Hall, 5th edition, 1996.
4. Mann, F.G. & Saunders, B.C. Practical Organic Chemistry Orient-Longman, 1960.
5. Harris, D.C.Exploring Chemical Analysis, 9 Ed. New York, W.H. Freeman, 2016.
th

Course prerequisites: To study this course, a student must have Opted Sem-V Theory Ppaer-1 &2

………………………………………………………………………………………………..
………………………………………………………………………………………………..
43
Semester-VI Paper-1
Course Title: Organic Synthesis B
Programme: Degree in Bachelor of Semester: VI

Year: Three
Science
Paper-1 Theory Compulsory Subject: Chemistry
Course Code:B020601T
Course Title: Organic Synthesis B
Course outcomes: This paper provides detailed knowledge of synthesis of various class of organic compounds and
functional groups inter conversion. Organic synthesis is the most important branch of organic chemistry which provides
jobs in production & QC departments related to chemicals, drugs, medicines, FMCG etc. industries.
The study of natural products and heterocyclic compounds offers an excellent strategy toward identifying novel
biological probes for a number of diseases. Historically, natural products have played an important role in the
development of pharmaceutical drugs for a number of diseases including cancer and infection.
 It relates and gives an analytical aptitude for synthesizing various industrially important compounds.
 Learn the different types of alkaloids, & terpenes etc and their chemistry and medicinal importance.
 Explain the importance of natural compounds as lead molecules for new drug discovery.
Credits: 4 Elective
Unit Topics No. of

Lectures
Reagents in Organic Synthesis
A detailed study of the following reagents in organic transformations
I 6
Oxidation with DDQ, CAN and SeO2, mCPBA, Jones Oxidation, PCC, PDC, PFC, Collin’s
reagent and ruthenium tetraoxide. Reduction with NaBH4, LiAlH4, Meerwein-Ponndorf-Verley
(MPV) reduction, Wilkinson's catalyst, Birch reduction, DIBAL-H
44
Organometallic Compounds-Organomagnesium compounds: the Grignard reagents, formation,
II structure and chemical reactions. Organozinc compounds: formation and chemical 4

reactions. Organolithium compounds: formation and chemical reactions.
Chemistry of Aldehydes and ketones: Nomenclature and structure of the carbonyl groups,
synthesis of aldehydes and ketones with particular reference to the synthesis of aldehydes from acid
chlorides, synthesis of aldehydes and ketones uses 1, 3-dithianes, synthesis of ketones from nitrites
and from carboxylic acids, Physical properties. Mechanism of nucleophillic additions to carbonyl
III group with particular emphasis on benzoin, aldol, Perkin and Knoevenagel condensations,
10
Condensation with ammonia and its derivatives. Wittig reaction, Mannich reaction. Oxidation of
aldehydes, Cannizzaro reaction, MPV, Clemmensen, Wolff-Kishner, LiAlH4 and NaBH4
reductions. Halogenation of enolizable ketones An introduction to α, β unsaturated aldehydes and
Ketones.
Carboxylic acids and their Functional Derivatives

Nomenclature and classification of aliphatic and aromatic carboxylic acids. Preparation and
reactions. Acidity (effect of substituents on acidity) and salt formation, Reactions: Mechanism of
reduction, substitution in alkyl or aryl group. Preparation and properties of dicarboxylic acids such
as oxalic, malonic, succinic, glutaric, adipic and phthalic acids and unsaturated carboxylic acids
IV 8
such as acrylic, crotonic and cinnamic acids, Reactions: Action of heat on hydroxy and amino acids,
and saturated dicarboxylic acids, stereospecific addition to maleic and fumaric acids. Preparation
and reactions of acid chlorides, acid anhydrides, amides and esters, acid and alkaline hydrolysis of
esters, trans-esterification.
Organic Synthesis via Enolates

Acidity of α-hydrogens, alkylation of diethyl malonate and ethyl acetoacetate, Synthesis of ethyl
V acetoacetate: the Claisen condensation, Keto-enol tautomerism of ethyl acetoacetate. Alkylation of 5

1, 3-dithianes, Alkylation and acylation of enamines.
Organic Compounds of Nitrogen- Preparation of nitroalkanes and nitroarenes, Chemical

reactions of nitroalkanes. Mechanisms of nucleophilic substitution in nitroarenes and their
reductions in acidic, neutral and alkaline media, Picric acid. Halonitroarenes: reactivity, Structure
and nomenclature of amines, physical properties, Stereochemistry of amines, Separation of a
VI 10
mixture of primary, secondary and tertiary amines. Structural features effecting basicity of amines.
Amine salts as phase-transfer catalysts, Preparation of alkyl and aryl amines (reduction of nitro
compounds, nitrities), reductive amination of aldehydic and ketonic compounds, Gabriel-
phthalimide reaction, Hofmann bromamide reaction. Reactions of amines, electrophilic aromatic
45
substituton in aryl amines, reactions of amines with nitrous acid. Synthetic transformations of aryl
diazonium salts, azo coupling
Heterocyclic Chemistry
Molecular orbital picture and aromatic characteristics of pyrrole, furan, thiophene and pyridine,
Methods of synthesis and chemical reactions with particular emphasis on the mechanism of
electrophilic substitution, Mechanism of nucleophilic substitution reaction in pyridine derivatives,
VII 10
Comparison of basicity of pyridine, piperidine and pyrrole. Introduction to condensed five and six
membered heterocycles, Preparation and reactions of indole, quinoline and isoquinoline with
special reference to Fisher indole synthesis, Skraup synthesis and Bischler-Nepieralski synthesis,
Mechanism of electrophilc substitution reactions of indole, quinoline and isoquinoline
Natural Products
Alkaloids & Terpenes: Natural occurrence, General structural features, their physiological
VIII action, Hoffmann’s exhaustive methylation, Emde’s modification;. Medicinal importance of 7
Nicotine, Hygrine, Quinine, Morphine, Cocaine, and Reserpine. Natural Occurrence and
classification of terpenes, isoprene rule.
Suggested Readings:
24. March, J. Advanced Organic Chemistry, Fourth edition, Wiley.
25. Acheson, R.M. Introduction to the Chemistry of Heterocyclic compounds, John Welly& Sons (1976).
26. Finar, I. L. Organic Chemistry (Volume 1), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).
27. Finar, I. L. Organic Chemistry (Volume 2: Stereochemistry and the Chemistry of Natural
28. Products), Dorling Kindersley (India) Pvt. Ltd. (Pearson Education).
29. Singh, J.; Ali, S.M. & Singh, J. Natural Product Chemistry, Pragati Prakashan (2010).
30. Organic Chemistry III, Krishna Prakashan Media, Meerut , Third Eddition, 2019
This course compulsory for the students of following subjects: Chemistry in 12 th Class

46
Or

Course prerequisites: To study this course, a student must have Passed Sem-V Theory paper-1

………………………………………………………………………………………………..
………………………………………………………………………………………………..
Semester-VI Paper-2
Course Title: Chemical Energetics and Radio Chemistry
Programme: Degree in Bachelor of Semester: VI

Year: Three
Science
Paper-2 Theory Elective Subject: Chemistry
Course Code: B020602T

Course Title: Chemical Energetics and Radio Chemistry
Course outcomes: Upon successful completion of this course students should be able to describe laws of
thermodynamics and its applications, phase equilibria of one and two component system, electro chemistry ,ionic
equilibrium applications of conductivity and potentiometric measurements
Credits: 4 Elective
Unit Topics No. of

Lectures
Thermodynamics-1 :
First Law of Thermodynamics : Statement , definition of internal energy and enthalpy. Heat
capacity ,heat capacities at constant volume and pressure and their relationship. Joule's law – Joule-
Thomson coefficient and inversion temperature . Calculation of w, q, dU & dH for the expansion of
I ideal gases under isothermal and adiabatic conditions for reversible process.
8
Thermochemistry: Standard state, standard enthalpy of formation – Hess's law of heat summation
and its applications. Heat of reaction at constant pressure and at constant volume . Enthalpy of
neutralization . Bond dissociation energy and its calculation from thermo-chemical data , temperature
dependence of enthalpy. Kirchhoff's equation.
II Thermodynamics II
10
47
Second Law of Thermodynamics, Need for the law, different statements of the law, Carnot cycle
and its efficiency. Carnot theorem. Thermodynamic scale of temperature.
Concept of Entropy, Entropy as a state function, entropy as a function of V & T, entropy as a
function of P & T, entropy change in physical change, Clausius inequality , entropy as a criteria of
spontaneity and equilibrium. Entropy change in ideal gases and mixing of gases. Gibbs and
Helmholtz Functions
Gibbs function (G) and Helmhotz function (A) as thermodynamic quantities. A & G as criteria for
thermodynamic equilibrium and spontaneity, their advantage over entropy change, Variation of G
and A with P, V and T.
Third Law of Thermodynamics ; Nernst heat theorem , statement and concept of residual entropy.
Nernst distribution law – Thermodynamic derivation, applications .
Electrochemistry: Electrical transport:- Conduction in metals and in electrolyte solutions, specific
conductance molar and equivalent conductance, measurement of equivalent conductance, variation
of molar, equivalent and specific conductances with dilution. Migration of ions and Kohlrausch law
III , Arrhenius theory of electrolyte dissociation and its limitations. Weak and strong electrolytes . 8
Ostwald's dilution law, its uses and limitations . Debye-Huckel-Onsager equation for strong
electrolytes (elementary treatment only) . Transport number, definition and determination by Hittorf
method and moving boundary method.
Ionic Equilibrium: Electrode reactions, Nernst equation, derivation of cell EMF and single electrode
potential, standard hydrogen electrode-reference electrodes and their applications, standard electrode
potential, sign conventions, Electrolytic and Galvanic cells–Reversible and irreversible cells,
IV conventional representation of electrochemical cells. EMF of a cell and its measurement. Definition
10
of pH and pKa , determination of pH using hydrogen, quinhydrone and glass electrodes by
potentiometric methods. Buffers – Mechanism of buffer action, Henderson-Hazel equation,
application of buffer solution. Hydrolysis of salts
Photo Chemistry: Interaction of radiation with matter, difference between thermal and
photochemical processes . Laws of photochemistry: Grothus- Drapper law, Stark-Einstein law,
Jablonski diagram depicting various processes occurring in the excited state, qualitative description
V 04
of fluorescence, phosphorescence, non-radiative processes (internal conversion, intersystem
crossing), quantum yield, photosensitized reactions – energy transfer processes (simple examples),
kinetics of photochemical reaction.
48
Colligative Properties-Ideal and non-ideal solutions, methods of expressing concentrations of
solutions, activity and activity coefficient. Dilute solution, colligative properties, Raoult's law,
relative lowering of vapour pressure, molecular weight determination, Osmosis, law of osmotic
pressure and its measurement, determination of molecular weight from osmotic pressure, Elevation
VI 6
of boiling point and depression of freezing, Thermodynamic derivation of relation between molecular
weight and elevation in boiling point and depression in freezing point. Experimental methods for
determining various colligative properties. Abnormal molar mass, Van't Hoff factor, Colligative
properties of degree of dissociation and association of solutes.
Surface Chemistry
Adsorption: Physical and chemical adsorption; Freundlich and Langmuir adsorption isotherms;
multilayer adsorption and BET isotherm (no derivation required); Gibbs adsorption isotherm and
surface excess; Heterogenous catalysis (single reactant);
VI
07
I Colloids:Lyophobic and lyophilic sols, Origin of charge and stability of lyophobic
colloids,Coagulation and Schultz-Hardy rule, Zeta potential and Stern double layer (qualitative idea),
Tyndall effect; Electrokinetic phenomena (qualitative idea only); Stability of colloids and zeta
potential; Micelle formation
Radiochemistry
Natural and induced radioactivity; radioactive decay-a-decay, b-decay, g-decay; neutrom emission,
positrom emission, electron capture; unit of radioactivity (Curie); half life period; Geiger-Nuttal rule,
VI
07
II radioactive displacement law, radioactive series. Measurement of radioactivity: ionization chamber,
Geiger counters, scintillation counters. Applications: energy tapping, dating of objects, neutron
activation analysis, isotopic labelling studies, nuclear medicine-99mTc radiopharmaceuticals
Suggested Readings:
1. Foye, W.O., Lemke, T.L. & William, D.A.: Principles of Medicinal Chemistry, 4th ed., B..I. Waverly Pvt.
Ltd. New Delhi.
2. Peter Atkins & Julio De Paula, Physical Chemistry 9th Ed., Oxford University Press (2010).
3. Metz, C. R. Physical Chemistry 2nd Ed., Tata McGraw-Hill (2009).
6. Castellan, G. W. Physical Chemistry 4th Edn. Narosa (2004).
7. Allen Bard ,J Larry . Faulkner R ,Fundamentals of Electrochemical methods –fundamentals and
applications ,new York John ,Wiley &sons , 2001
8. H. J. Arnikar, Essentials of Nuclear Chemistry, 4th ed., New Age International, New Delhi, 1995.
9. Bariyar,and Goyal, Physical Chemistry-II, Krishna Prakashan Media, Meerut , Third Eddition, 2019
https://www.coursera.org/learn/physical-chemistry
https://www.mooc-list.com/tags/physical-chemistry
https://www.openlearning.com/courses/introduction-to-physical-chemistry/
49

Or

Course prerequisites: To study this course, a student must have had the chemistry in class 12th , Physics in
12th

………………………………………………………………………………………………..
………………………………………………………………………………………………..
50
Semester VI, Paper-3 (Practical)
Course Title: Analytical Methods
Programme: Degree in Year: Three Semester: IV

Bachelor of Science
Course Title: Analytical Methods
Course Outcomes: Upon successful completion of this course students should be able to quantify the product obtained
through gravimetric method; determination of Rƒ values and identification of organic compounds through paper and
thin layer chromatography laboratory techniques: perform thermo chemical reactions
Credits: 2 Elective
Practical 60 h
No of
Unit Topics
Lectures
Gravimetric Analysis
1. Analysis of Cu as CuSCN,
I 2. Analysis of Ni as Ni (dimethylgloxime) 30
3. Analysis of Ba as BaSO4.
Paper Chromatography
Ascending and Circular. Determination of Rƒ values and identification of organic
II compounds: Separation of a mixture of phenylalanine and glycine. Alanine and aspartic 8

acid Leucine and glutamic acid. Spray reagent – ninhydrin. Separation of a mixture of D,
L – alanine, glycine, and L-leucine using n-butanol:acetic acid: water (4:1:5). Spray reagent
51
– ninhydrin. Separation of monosaccharaides – a mixture of D- galactose and D -fructose
using n- butanol: acetone: water (4:5:1). Spray reagent – aniline hydrogen phthalate
Thin Layer Chromatography

Determination of Rƒ values and identification of organic compounds:Separation of green
leaf pigments (spinach leaves may be used) Preparation of separation of 2,4-
III 8
dinitrophenylhydrazones of acetone, 2-butanone, hexan-2, and 3-one using toluene and
light petroleum (40:60)
Separation of a mixture of dyes using cyclohexane and ethyl acetate (8.5:1.5)
Thermochemistry
1. To determine the solubility of benzoic acid at different temperatures and to determine
∆H of the dissolution process
2. To determine the enthalpy of neutralization of a weak acid/weak base versus strong
IV 14
base/strong acid and determine the enthalpy of ionization of the weak acid/weak base
3. To determine the enthalpy of solution of solid calcium chloride and calculate the
lattice energy of calcium chloride from its enthalpy data using Born-Haber cycle
Suggested Readings:
1. Skoog .D.A., West.D.M and Holler .F.J., “Analytical Chemistry: An Introduction”, 7th edition, Saunders
college publishing, Philadelphia,(2010).
2. Larry Hargis.G” Analytical Chemistry: Principles and Techniques” Pearson©(1988 )

Course prerequisites: To study this course, a student must have had the chemistry in 12 th class

………………………………………………………………………………………………..
………………………………………………………………………………………………..
52

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Semester-wise Titles of the Papers in B.Sc.

Purpose of the Program

CERTIFICATE IN BIOORGANIC AND MEDICINAL CHEMISTRY

Third DEGREE IN BACHELOR OF SCIENCE

2 1. Chemical kinetics Nil

1. Reagents in Organic synthesis 1. Gravimetric Analysis

Certificate in Bioorganic and Medicinal Chemistry

1 I B020101T Fundamentals of Chemistry Theory 4

B020102P Quantitative Analysis Practical 2

1 II B020201T Bioorganic and Medicinal Chemistry Theory 4

B020202P Biochemical Analysis Practical 2

Paper-1 Theory Subject: Chemistry

Course Code:B020101T Course Title: Fundamentals of Chemistry

Max. Marks: 25+75 Min. Passing Marks:…………

Total No. of Lectures = 60

Unit Topics No. of

V reagents – electrophiles and nucleophiles, Types of organic reactions, Energy considerations. 10

Assessment and presentation of Assignment (10 marks)

Overall performance throughout the semester, Discipline, (05 marks)

Suggested equivalent online courses:

Max. Marks: 25+75 = 100 Min. Passing Marks:

3. Determination of Biological oxygen demand (BOD).

3. Estimation of oxalic acid by titrating it with KMnO4.

Suggested Continuous Evaluation Methods:

Suggested equivalent online courses:

Course Code: B020201T Course Title: Bioorganic and Medicinal Chemistry

Max. Marks: 25+75 Min. Passing Marks:………

Total No. of Lectures = 60

Unit Topics No. of

Suggested Continuous Evaluation Methods:

Assessment and presentation of Assignment (10 marks)

Overall performance throughout the semester (05 marks)

Programme: Certificate in Semester: II

Max. Marks: 25+75 = 100 Min. Passing Marks:

Qualitative and quantitative analysis of Proteins, amino acids and Fats

Determination and identification of Nucleic Acids

Synthesis of Simple drug molecules

Suggested Continuous Evaluation Methods:

Diploma in Chemical Dynamics and Analytical Techniques

2 III B020301T Chemical Dynamics & Coordination Theory 4

B020302P Physical Analysis Practical 2

IV B020401T Quantum Mechanics and Analytical Theory 4

B020402P Instrumental Analysis Practical 2

Course Code:B020301T Course Title: Chemical Dynamics & Coordination Chemistry

Max. Marks: 25+75 Min. Passing Marks:…………

Total No. of Lectures = 60

Unit Topics No. of

Inorganic Spectroscopy and Magnetism

Overall performance throughout the semester ( Discipline, (05 marks)

Suggested equivalent online courses:

Programme: Diploma in Semester: III

Max. Marks: 25 +75 Min. Passing Marks:

Surface Tension and Viscosity

Suggestive digital platforms web links

Suggested Continuous Evaluation Methods:

Suggested equivalent online courses:

Course Code: BO20401T

Max. Marks: 25+75 Min. Passing Marks:……………