Papers by Muhammad Atif Imran
International Journal of Sciences: Basic and Applied Research (IJSBAR), 2021
Colorectal cancer is considering a communal health problem and in the whole world, its number is ... more Colorectal cancer is considering a communal health problem and in the whole world, its number is third in all cancers that were diagnosed. It causes a significant burden in terms of sickness and death with the estimation of seven lakhs annual deaths. In many countries of the world western way of life is rapidly adopted that is a welldebated factor for colorectal cancer and in term of primary preventive measures, it could be besieged. Comparatively slow advancement of this cancer allows severe reduction of occurrence and death rate with the help of secondary prevention. These facts motivate primary care physicians to play a key role in health plans that improve prevention and rapid diagnosis. In ancient years, the targeted therapies with combinational treatment have proven to be very effective for specific colorectal cancer patients. These therapies are epidermal growth factor, receptor inhibitor, and growth factor. As the advancements in clinic and science have visible that give new treatment options for metastatic colorectal cancer, the five-year existence rate is still fourteen percent low. But in other subtypes of colorectal cancer, the results may not be successful and not highly explored. We can reduce side effects and make the treatment effect by using alternative therapies instead of traditional therapies such as anticancer drugs, probiotics, etc. Herein, some major topics related to CRC in recent literature have been reviewed, to acknowledge its malignancy, risk, and defensive factors, along with the screening methodologies. Moreover, we also debate over preventive as well as screening strategies to fight against CRC.
International Journal of Sciences: Basic and Applied Research (IJSBAR), 2021
About 150 and about 35 million human beings are infected with HCV (hepatitis C virus) as well as ... more About 150 and about 35 million human beings are infected with HCV (hepatitis C virus) as well as HIV (human immunodeficiency virus) respectively. The increasing stress of HIV/HCV coinfection is supposed to infect five to seven million individuals globally due to their coinciding approaches of procurement. Co-infection of HCV/HIV in patients caused them to suffer from more liver-associated mortality and anguish. This paper aims to investigate the spread rate of the HIV and HCV coinfection in District Faisalabad. In this paper, blood samples of patients are evaluated and tested for anti-HIV/HCV antibodies employing the ICT (immune chromatography technique) for HIV/HCV confections. The six out 30 confirmed patients (real-time PCR) for HIV infection who also have HCV infection were analyzed for additional provisional clinical examination. In these patients, the hemoglobin (17.38±0.159 per dL), ALT (77 uL-1) and Hematocrit (50.60±0.255%) levels increased significantly than standard reference values. On the body, these facts could be developed due to HIV/HCV co-infection burden. An inverse relation has been demonstrated by these coinfected patients in the levels of hemoglobin as well as in platelets. With the usages of better supplements/nutrients, the above differential values can be improved and ultimately beneficial for the survival of the infected individuals. The Current paper could be convenient for appropriate perpetuation of HIV/HCV co-infected patients under related treatment.
International Journal of Biosciences (IJB), 2020
Cancer presently exists as the major pathological state in developed and emergent nations equally... more Cancer presently exists as the major pathological state in developed and emergent nations equally which is characterized by the uncontrolled division of cells and is fatal. People prefer anticancer plant products to treat cancer due to the increased mortality related to undetected growth in addition to its toxic reactions to chemotherapy and radiotherapy. In recent years, eastern medicine provided a profitable substitute for allopathic medicine against cancer. There have been considerable researches on plants for treating cancer, and many of the plant products have been sold as anticancer medicine, depending on the conventional uses and experimental reports. The anticancer property of medicinal plants is due to their antioxidant activity which has been described in many reports. Thus, after isolation (by using chromatographic and crystallization techniques) and identification using LCMS spectra, IR, and NMR, many combinations of the active components can be prepared and should be further evaluated for their synergic effects. The development of a systemized dose and dosage procedure may perform an exceptional role in the cure of tumors. The rate at which cancer develops is a necessary and effective endeavor for the good health of human beings. Further investigations are required to analyze the mechanisms of anti-malignant action of active compounds from new plants and the use of standard herbal remedies.
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Papers by Muhammad Atif Imran