Pages that link to "Q81510439"

The following pages link to Three key residues underlie the differential affinity of the TGFbeta isoforms for the TGFbeta type II receptor (Q81510439):

Displaying 38 items.

• TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs (Q24297719) (← links)
• Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding (Q24310182) (← links)
• A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor (Q27643809) (← links)
• Ternary Complex of Transforming Growth Factor- 1 Reveals Isoform-specific Ligand Recognition and Receptor Recruitment in the Superfamily (Q27660131) (← links)
• The TβR-I Pre-Helix Extension Is Structurally Ordered in the Unbound Form and Its Flanking Prolines Are Essential for Binding (Q27671571) (← links)
• Complexities of TGF-β targeted cancer therapy (Q27693607) (← links)
• A high confidence, manually validated human blood plasma protein reference set (Q28756902) (← links)
• TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs (Q33572051) (← links)
• An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling (Q33615675) (← links)
• Peptide ligands that use a novel binding site to target both TGF-β receptors. (Q33708971) (← links)
• TGF- β: an important mediator of allergic disease and a molecule with dual activity in cancer development (Q33809976) (← links)
• Ectodomain shedding of TβRIII is required for TβRIII-mediated suppression of TGF-β signaling and breast cancer migration and invasion (Q34081397) (← links)
• TGFβ signaling promotes juvenile granulosa cell tumorigenesis by suppressing apoptosis (Q34422499) (← links)
• Structure of the ternary signaling complex of a TGF-beta superfamily member (Q34589783) (← links)
• TGFβ2 regulates hypothalamic Trh expression through the TGFβ inducible early gene-1 (TIEG1) during fetal development (Q35555559) (← links)
• TGFβ isoforms and receptors mRNA expression in breast tumours: prognostic value and clinical implications (Q35878410) (← links)
• Modeling and fitting protein-protein complexes to predict change of binding energy (Q36898375) (← links)
• Controversy surrounding the increased expression of TGF beta 1 in asthma (Q36950562) (← links)
• Expression, purification and characterization of BG(E)RII: a novel pan-TGFbeta inhibitor (Q36953792) (← links)
• Betaglycan has two independent domains required for high affinity TGF-beta binding: proteolytic cleavage separates the domains and inactivates the neutralizing activity of the soluble receptor. (Q37484255) (← links)
• TGF-beta3 and cancer: a review (Q37573098) (← links)
• Homomeric and heteromeric complexes among TGF-β and BMP receptors and their roles in signaling (Q37868339) (← links)
• Production, Isolation, and Structural Analysis of Ligands and Receptors of the TGF-β Superfamily (Q38823276) (← links)
• Structural Biology and Evolution of the TGF-β Family (Q38957057) (← links)
• Secretome Analysis of Multiple Pancreatic Cancer Cell Lines Reveals Perturbations of Key Functional Networks (Q39670851) (← links)
• Modulation of the functional binding sites for TGF-beta on the type II receptor leads to suppression of TGF-beta signaling (Q40200583) (← links)
• Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma (Q40989877) (← links)
• Endotoxin-induced endothelial fibrosis is dependent on expression of transforming growth factors β1 and β2. (Q42932656) (← links)
• Transforming growth factor-β gene silencing using adenovirus expressing TGF-β1 or TGF-β2 shRNA. (Q43727484) (← links)
• Binding Properties of the Transforming Growth Factor-β Coreceptor Betaglycan: Proposed Mechanism for Potentiation of Receptor Complex Assembly and Signaling. (Q43783586) (← links)
• Transforming growth factor-beta1 is the predominant isoform required for breast cancer cell outgrowth in bone (Q46200196) (← links)
• Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization. (Q47898529) (← links)
• Wound healing: from embryos to adults and back again (Q48017094) (← links)
• Structure-guided engineering of TGF-βs for the development of novel inhibitors and probing mechanism (Q90347478) (← links)
• Structural biology of the TGFβ family (Q90594661) (← links)
• Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family (Q90633876) (← links)
• Integrin-Mediated TGFβ Activation Modulates the Tumour Microenvironment (Q92784010) (← links)
• Directed Blocking of TGF-β Receptor I Binding Site Using Tailored Peptide Segments to Inhibit its Signaling Pathway (Q98946885) (← links)