Pages that link to "Q42364302"
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The following pages link to C9orf72 is required for proper macrophage and microglial function in mice (Q42364302):
Displaying 50 items.
- There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS (Q26750577) (← links)
- C9orf72's Interaction with Rab GTPases-Modulation of Membrane Traffic and Autophagy (Q28069365) (← links)
- C9orf72, member of C9orf72-SMCR8 complex (Q28563691) (← links)
- A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy (Q29465530) (← links)
- The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway (Q29465536) (← links)
- Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling (Q29465544) (← links)
- C9orf72 binds SMCR8, localizes to lysosomes, and regulates mTORC1 signaling (Q29465782) (← links)
- Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease (Q30811549) (← links)
- Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation (Q30847257) (← links)
- Immune dysregulation may contribute to disease pathogenesis in spinal muscular atrophy mice (Q33614675) (← links)
- Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD. (Q33614771) (← links)
- C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten (Q33614811) (← links)
- Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities? (Q33621868) (← links)
- Pathology of callosal damage in ALS: An ex-vivo, 7 T diffusion tensor MRI study (Q33676258) (← links)
- Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes (Q33746245) (← links)
- A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response (Q33796396) (← links)
- Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD. (Q33863540) (← links)
- Mouse Models of C9orf72 Hexanucleotide Repeat Expansion in Amyotrophic Lateral Sclerosis/ Frontotemporal Dementia (Q33875570) (← links)
- SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits (Q33891056) (← links)
- Cell-type specific differences in promoter activity of the ALS-linked C9orf72 mouse ortholog. (Q33915834) (← links)
- Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers (Q36321473) (← links)
- Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs (Q36880235) (← links)
- Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture (Q37380290) (← links)
- Forward Genetic Screen in Caenorhabditis elegans Suggests F57A10.2 and acp-4 As Suppressors of C9ORF72 Related Phenotypes (Q37401038) (← links)
- Elevated TMEM106B levels exaggerate lipofuscin accumulation and lysosomal dysfunction in aged mice with progranulin deficiency (Q37609848) (← links)
- Loss of C9orf72 function leads to autoimmunity (Q37666980) (← links)
- Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons (Q38739863) (← links)
- Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells (Q38741408) (← links)
- Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits (Q38760731) (← links)
- Hematopoietic stem and progenitor cells as novel prognostic biomarkers of longevity in a murine model for amyotrophic lateral sclerosis (Q38816820) (← links)
- Hypo- and Hyper-Assembly Diseases of RNA-Protein Complexes (Q38855284) (← links)
- Review: Induced pluripotent stem cell models of frontotemporal dementia (Q38862587) (← links)
- Precision medicine, genomics and drug discovery (Q38931024) (← links)
- Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene (Q38952327) (← links)
- Role of the JAK/STAT signaling pathway in regulation of innate immunity in neuroinflammatory diseases. (Q38974101) (← links)
- Decoding ALS: from genes to mechanism. (Q39004348) (← links)
- TBK1: a new player in ALS linking autophagy and neuroinflammation. (Q39113949) (← links)
- The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD. (Q39153670) (← links)
- C9orf72: At the intersection of lysosome cell biology and neurodegenerative disease (Q39165154) (← links)
- The helminth product, ES-62 modulates dendritic cell responses by inducing the selective autophagolysosomal degradation of TLR-transducers, as exemplified by PKCδ. (Q39169396) (← links)
- Protein-Remodeling Factors As Potential Therapeutics for Neurodegenerative Disease. (Q39178504) (← links)
- Antisense Oligonucleotides: Translation from Mouse Models to Human Neurodegenerative Diseases (Q39391538) (← links)
- Multifaceted role of SMCR8 as autophagy regulator. (Q39428501) (← links)
- Microglia and C9orf72 in neuroinflammation and ALS and frontotemporal dementia (Q39454075) (← links)
- RNA Misprocessing in C9orf72-Linked Neurodegeneration (Q39458329) (← links)
- C9ORF72 is a GDP/GTP exchange factor for Rab8 and Rab39 and regulates autophagy (Q39520699) (← links)
- The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy (Q39662062) (← links)
- C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers. (Q39850417) (← links)
- New insights into SMA pathogenesis: immune dysfunction and neuroinflammation (Q40140411) (← links)
- ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks (Q40968548) (← links)