Pages that link to "Q40118489"

The following pages link to Pharmacologic characterization of a potent inhibitor of class I phosphatidylinositide 3-kinases. (Q40118489):

Displaying 50 items.

• PI3K/AKT/mTOR Pathway in Angiogenesis (Q21129332) (← links)
• Molecular insights into the membrane-associated phosphatidylinositol 4-kinase IIα (Q24293130) (← links)
• mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1) (Q24324148) (← links)
• Updates of mTOR inhibitors (Q24607170) (← links)
• A systematic screen for protein-lipid interactions in Saccharomyces cerevisiae (Q24621326) (← links)
• The mTOR signalling pathway in human cancer (Q24627306) (← links)
• Akt and autophagy cooperate to promote survival of drug-resistant glioma (Q24629677) (← links)
• SV40-induced expression of calretinin protects mesothelial cells from asbestos cytotoxicity and may be a key factor contributing to mesothelioma pathogenesis (Q24658316) (← links)
• Targeting p110gamma in gastrointestinal cancers: attack on multiple fronts (Q26823575) (← links)
• Autophagy and neurodegeneration (Q26991692) (← links)
• Autophagy modulation as a potential therapeutic target for diverse diseases (Q27010076) (← links)
• The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors (Q27659013) (← links)
• Discovery of 4-Amino-1-(7 H -pyrrolo[2,3- d ]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt) (Q27659777) (← links)
• Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors. (Q27851896) (← links)
• Reduced Warburg effect in cancer cells undergoing autophagy: steady- state 1H-MRS and real-time hyperpolarized 13C-MRS studies (Q28541488) (← links)
• Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcoma (Q28541805) (← links)
• PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen Peroxide (Q28553400) (← links)
• Active PI3K pathway causes an invasive phenotype which can be reversed or promoted by blocking the pathway at divergent nodes (Q28730141) (← links)
• Inhibition of mTOR-kinase destabilizes MYCN and is a potential therapy for MYCN-dependent tumors (Q28817295) (← links)
• Targeting PI3K signalling in cancer: opportunities, challenges and limitations (Q29617685) (← links)
• ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change. (Q33356400) (← links)
• Molecular imaging of phosphorylation events for drug development (Q33388737) (← links)
• Proteomic analysis of phosphoproteins sensitive to a phosphatidylinositol 3-kinase inhibitor, ZSTK474, by using SELDI-TOF MS (Q33424100) (← links)
• Targeting the PI3K/AKT/mTOR signaling network in acute myelogenous leukemia (Q33493174) (← links)
• Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor (Q33597663) (← links)
• The biology of ovarian cancer: new opportunities for translation (Q33622369) (← links)
• Fluorescence Polarization and Time-Resolved Fluorescence Resonance Energy Transfer Techniques for PI3K Assays (Q33652579) (← links)
• Tumor vascular changes mediated by inhibition of oncogenic signaling (Q33671385) (← links)
• Oncogenes and pathway identification using filter-based approaches between various carcinoma types in lung (Q33675232) (← links)
• The PIK3CA gene as a mutated target for cancer therapy (Q33699378) (← links)
• Discovery of novel anticancer therapeutics targeting the PI3K/Akt/mTOR pathway (Q33852403) (← links)
• A theoretical entropy score as a single value to express inhibitor selectivity (Q33870615) (← links)
• Small-molecule inhibitors of the PI3K signaling network (Q33883982) (← links)
• Blocking phosphoinositide 3-kinase activity in colorectal cancer cells reduces proliferation but does not increase apoptosis alone or in combination with cytotoxic drugs (Q33901504) (← links)
• Activity of any class IA PI3K isoform can sustain cell proliferation and survival. (Q33952917) (← links)
• The phosphoinositide 3-kinase inhibitor PI-103 downregulates choline kinase alpha leading to phosphocholine and total choline decrease detected by magnetic resonance spectroscopy. (Q33959529) (← links)
• Probing the probes: fitness factors for small molecule tools (Q34001269) (← links)
• The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients. (Q34024558) (← links)
• The complexes of mammalian target of rapamycin. (Q34116818) (← links)
• Autophagy-regulating small molecules and their therapeutic applications (Q34147157) (← links)
• PI3K and mTOR signaling pathways in cancer: new data on targeted therapies (Q34164683) (← links)
• PI3K: from the bench to the clinic and back (Q34195495) (← links)
• Two hits are better than one: targeting both phosphatidylinositol 3-kinase and mammalian target of rapamycin as a therapeutic strategy for acute leukemia treatment. (Q34260622) (← links)
• PI3Kα Inhibitors That Inhibit Metastasis (Q34416746) (← links)
• Glucose uptake in brown fat cells is dependent on mTOR complex 2-promoted GLUT1 translocation (Q34483836) (← links)
• Targeting the PI3K/Akt/mTOR pathway in hepatocellular carcinoma. (Q34632966) (← links)
• Activation of 3-phosphoinositide-dependent kinase 1 (PDK1) and serum- and glucocorticoid-induced protein kinase 1 (SGK1) by short-chain sphingolipid C4-ceramide rescues the trafficking defect of ΔF508-cystic fibrosis transmembrane conductance regula (Q34774491) (← links)
• Requirement for the eIF4E binding proteins for the synergistic down-regulation of protein synthesis by hypertonic conditions and mTOR inhibition (Q34936880) (← links)
• Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers. (Q34995420) (← links)
• A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes (Q35000701) (← links)