Pages that link to "Q33225547"
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The following pages link to MRS2500 [2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate], a potent, selective, and stable antagonist of the platelet P2Y1 receptor with strong antithrombotic activity in mice (Q33225547):
Displaying 50 items.
- G-protein-coupled receptors signaling pathways in new antiplatelet drug development (Q26864951) (← links)
- In silico Approach for Anti-Thrombosis Drug Discovery: P2Y1R Structure-Based TCMs Screening (Q28817785) (← links)
- Par4 is required for platelet thrombus propagation but not fibrin generation in a mouse model of thrombosis (Q33267693) (← links)
- Characterization of purinergic P2X4 receptor channels expressed in anterior pituitary cells (Q33727399) (← links)
- Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic beta cells. (Q33828185) (← links)
- Pharmacochemistry of the platelet purinergic receptors. (Q33869922) (← links)
- Functionalized congener approach to the design of ligands for G protein-coupled receptors (GPCRs). (Q33926350) (← links)
- Functionalized congeners of P2Y1 receptor antagonists: 2-alkynyl (N)-methanocarba 2'-deoxyadenosine 3',5'-bisphosphate analogues and conjugation to a polyamidoamine (PAMAM) dendrimer carrier (Q34029528) (← links)
- P2Y nucleotide receptors: promise of therapeutic applications (Q34062142) (← links)
- Two disparate ligand-binding sites in the human P2Y1 receptor (Q34469331) (← links)
- Ser352 and Ser354 in the carboxyl terminus of the human P2Y1 receptor are required for agonist‐promoted phosphorylation and internalization in MDCK cells (Q34678084) (← links)
- Intestinal alkaline phosphatase regulates protective surface microclimate pH in rat duodenum (Q34981646) (← links)
- Development of selective high affinity antagonists, agonists, and radioligands for the P2Y1 receptor. (Q35050462) (← links)
- Agonists and antagonists for P2 receptors. (Q35064222) (← links)
- Activation and Regulation of Purinergic P2X Receptor Channels (Q35122793) (← links)
- Characterization of a novel function-blocking antibody targeted against the platelet P2Y1 receptor (Q35130686) (← links)
- P2Y receptors in the mammalian nervous system: pharmacology, ligands and therapeutic potential. (Q35163180) (← links)
- Anti‐platelet therapy: ADP receptor antagonists (Q35278165) (← links)
- The impact of commercially available purinergic ligands on purinergic signalling research (Q35693550) (← links)
- Purinergic signaling pathways in endocrine system (Q35952054) (← links)
- (N)-methanocarba-2MeSADP (MRS2365) is a subtype-specific agonist that induces rapid desensitization of the P2Y1 receptor of human platelets (Q36147741) (← links)
- Virtual screening leads to the discovery of novel non-nucleotide P2Y₁ receptor antagonists. (Q36168187) (← links)
- P2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells. (Q36323532) (← links)
- P2Y Receptors Sensitize Mouse and Human Colonic Nociceptors (Q36610295) (← links)
- Caged agonist of P2Y1 and P2Y12 receptors for light-directed facilitation of platelet aggregation. (Q36632204) (← links)
- Action of nucleosides and nucleotides at 7 transmembrane-spanning receptors (Q36635966) (← links)
- Platelet P2 receptors: old and new targets for antithrombotic drugs (Q36691632) (← links)
- Predominant role of spinal P2Y1 receptors in the development of neuropathic pain in rats. (Q37035751) (← links)
- Synthesis of enantiomerically pure (S)-methanocarbaribo uracil nucleoside derivatives for use as antiviral agents and P2Y receptor ligands. (Q37180134) (← links)
- The Molecular Mechanism of P2Y1 Receptor Activation (Q37200484) (← links)
- Discovery of Potential Orthosteric and Allosteric Antagonists of P2Y1R from Chinese Herbs by Molecular Simulation Methods. (Q37231713) (← links)
- Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli. (Q37341915) (← links)
- Stimulation of the P2Y1 receptor up-regulates nucleoside-triphosphate diphosphohydrolase-1 in human retinal pigment epithelial cells. (Q37588536) (← links)
- Molecular Pharmacology, Physiology, and Structure of the P2Y Receptors (Q37876544) (← links)
- P2 receptors and platelet function (Q38306634) (← links)
- The Antithrombotic Activity of EP224283, a Neutralizable Dual Factor Xa Inhibitor/Glycoprotein IIbIIIa Antagonist, Exceeds That of the Coadministered Parent Compounds (Q38335613) (← links)
- A novel enteric neuron-glia coculture system reveals the role of glia in neuronal development (Q38756893) (← links)
- Antagonism of P2Y1-induced vasorelaxation by acyl CoA: a critical role for palmitate and 3'-phosphate. (Q39760160) (← links)
- Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior (Q40394736) (← links)
- Calmodulin interacts with the platelet ADP receptor P2Y1 (Q41954849) (← links)
- Ligand binding to a G protein-coupled receptor captured in a mass spectrometer (Q42096462) (← links)
- Identification of a Different Agonist-Binding Site and Activation Mechanism of the Human P2Y1 Receptor (Q42645486) (← links)
- P2Y(1) receptors mediate inhibitory neuromuscular transmission in the rat colon (Q42951349) (← links)
- Effect of purinergic receptor activation on Na+-K+ pump activity, excitability, and function in depolarized skeletal muscle (Q43067146) (← links)
- Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase Cgamma2. (Q43129380) (← links)
- Novel excitatory effects of adenosine triphosphate on contractile and pacemaker activity in rabbit urethral smooth muscle. (Q43215061) (← links)
- 4-Benzothiazole-7-hydroxyindolinyl diaryl ureas are potent P2Y1 antagonists with favorable pharmacokinetics: low clearance and small volume of distribution (Q45369986) (← links)
- Demystifying P2Y1 Receptor Ligand Recognition through Docking and Molecular Dynamics Analyses (Q46252915) (← links)
- The P2Y1 receptor antagonist MRS2500 prevents carotid artery thrombosis in cynomolgus monkeys (Q46624805) (← links)
- Purinergic modulation of norepinephrine release and uptake in rat brain cortex: contribution of glial cells (Q49044156) (← links)