Vorinostat as a radiosensitizer for brain metastasis: a phase I clinical trial (Q87674625)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Vorinostat as a radiosensitizer for brain metastasis: a phase I clinical trial (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

main subject

phase I clinical trial

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Y.R. Lawrence

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Adam P. Dicker

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

author name string

Hak Choy

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Maria Werner-Wasik

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

David W Andrews

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

James J Evans

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Kevin D Judy

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Christopher J Farrell

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Yaron Moshel

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Adam C Berger

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Voichita Bar-Ad

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

publication date

13 April 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

Journal of Neuro-Oncology

14 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

volume

118

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

page(s)

313-319

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

Cooperation of the HDAC inhibitor vorinostat and radiation in metastatic neuroblastoma: efficacy and underlying mechanisms.

14 March 2020

cites work

1 reference

12 December 2020

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

1 reference

12 December 2020

Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors

1 reference

12 December 2020

Continuous intracranial administration of suberoylanilide hydroxamic acid (SAHA) inhibits tumor growth in an orthotopic glioma model

1 reference

12 December 2020

Modulation of radiation response by histone deacetylase inhibition

1 reference

12 December 2020

Vorinostat enhances the radiosensitivity of a breast cancer brain metastatic cell line grown in vitro and as intracranial xenografts

1 reference

12 December 2020

Histone deacetylation as a target for radiosensitization

1 reference

12 December 2020

Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas

1 reference

12 December 2020

Modulation of cellular radiation responses by histone deacetylase inhibitors

1 reference

12 December 2020

Phase I study of vorinostat in patients with advanced solid tumors and hepatic dysfunction: a National Cancer Institute Organ Dysfunction Working Group study

1 reference

12 December 2020

Phase I-II study of vorinostat plus paclitaxel and bevacizumab in metastatic breast cancer: evidence for vorinostat-induced tubulin acetylation and Hsp90 inhibition in vivo

1 reference

12 December 2020

Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study

1 reference

12 December 2020

A new prognostic index and comparison to three other indices for patients with brain metastases: an analysis of 1,960 patients in the RTOG database.

1 reference

12 December 2020

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

1 reference

12 December 2020

Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid

1 reference

12 December 2020

Histone deacetylase inhibitors radiosensitize human melanoma cells by suppressing DNA repair activity

1 reference

12 December 2020

Stereotactic radiosurgery for the management of brain metastases

1 reference

12 December 2020

Current neurosurgical management of brain metastases

1 reference

12 December 2020

Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group

1 reference

12 December 2020

Gastrointestinal toxicity of vorinostat: reanalysis of phase 1 study results with emphasis on dose-volume effects of pelvic radiotherapy

1 reference

12 December 2020

Vorinostat, a histone deacetylase inhibitor, enhances the response of human tumor cells to ionizing radiation through prolongation of gamma-H2AX foci

1 reference

12 December 2020

Histone deacetylase inhibitors

1 reference

12 December 2020

Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA

1 reference

12 December 2020

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor: effects on gene expression and growth of glioma cells in vitro and in vivo

1 reference

12 December 2020

Histone deacetylases and cancer: causes and therapies

1 reference

12 December 2020

Phase I study of vorinostat (suberoylanilide hydroxamic acid, NSC 701852) in combination with docetaxel in patients with advanced and relapsed solid malignancies.

1 reference

12 December 2020

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

1 reference

12 December 2020

A randomized phase II study of two doses of vorinostat in combination with 5-FU/LV in patients with refractory colorectal cancer

1 reference

12 December 2020

Clinical Trial Design in Brain Metastasis: Approaches for a Unique Patient Population

1 reference

12 December 2020

Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL)

1 reference

12 December 2020

Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study

1 reference

12 December 2020

Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma

1 reference

12 December 2020

Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials

1 reference

12 December 2020

Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial

1 reference

12 December 2020

Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study

1 reference

12 December 2020

Therapeutic advances in the treatment of brain metastases.

1 reference

12 December 2020

Inhibition of radiation-induced DNA repair and prosurvival pathways contributes to vorinostat-mediated radiosensitization of pancreatic cancer cells

1 reference

12 December 2020

Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks

1 reference

12 December 2020

Suberoylanilide hydroxamic acid (SAHA) has potent anti-glioma properties in vitro, ex vivo and in vivo

1 reference

12 December 2020

A randomized trial of surgery in the treatment of single metastases to the brain

1 reference

12 December 2020

HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics

1 reference

12 December 2020

10.1007/S11060-014-1433-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24728831%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference