Rituximab’s New Therapeutic Target: The Podocyte Actin Cytoskeleton (Q84245910)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632983%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

Rituximab's new therapeutic target: the podocyte actin cytoskeleton (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632983%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Rituximab’s New Therapeutic Target: The Podocyte Actin Cytoskeleton (English)

1 reference

https://api.crossref.org/works/10.1126/SCITRANSLMED.3002429

3 December 2024

author name string

Andrew C. Chan

1

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3 December 2024

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21632983

3 December 2024

publication date

1 June 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632983%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

2 February 2020

https://www.science.org/doi/pdf/10.1126/scitranslmed.3002429

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https://api.crossref.org/works/10.1126/SCITRANSLMED.3002429

Science Translational Medicine

3 December 2024

published in

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2 February 2020

volume

3

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2 February 2020

issue

85

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2 February 2020

page(s)

85ps21

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Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis

2 February 2020

cites work

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B-cell targeted therapies in human autoimmune diseases: an updated perspective

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Generation of biologically active linear and cyclic peptides has revealed a unique fine specificity of rituximab and its possible cross-reactivity with acid sphingomyelinase-like phosphodiesterase 3b precursor

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Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

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NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

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Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity

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Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.

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The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A.

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3 December 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632983%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference