NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes (Q80065016)

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28 December 2019

title

NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes (English)

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4

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author name string

Ayhan Cinar

1

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28 December 2019

Mingmin Chen

2

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28 December 2019

Brigitte Riederer

3

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Martin Wiemann

5

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Michael Manns

6

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Olivier Kocher

7

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Ursula Seidler

8

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publication date

29 March 2007

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28 December 2019

published in

Journal of Physiology

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volume

581

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issue

Pt 3

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page(s)

1235-1246

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pH regulation in single glomerular mesangial cells. I. Acid extrusion in absence and presence of HCO3-

28 December 2019

cites work

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12 December 2020

Isoforms of SLC26A6 mediate anion transport and have functional PDZ interaction domains

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12 December 2020

Functional characterization of three isoforms of the Na+/H+ exchanger stably expressed in Chinese hamster ovary cells. ATP dependence, osmotic sensitivity, and role in cell proliferation

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12 December 2020

Hyperosmolarity inhibits the Na+/H+ exchanger isoforms NHE2 and NHE3: an effect opposite to that on NHE1.

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12 December 2020

cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein

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12 December 2020

Effect of long-term hyperosmolality on the Na+/H+ exchanger isoform NHE-3 in LLC-PK1 cells

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12 December 2020

Structure-function of recombinant Na/H exchanger regulatory factor (NHE-RF)

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12 December 2020

Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger

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12 December 2020

NHE3 kinase A regulatory protein E3KARP binds the epithelial brush border Na+/H+ exchanger NHE3 and the cytoskeletal protein ezrin

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12 December 2020

Hypertonicity activates MAP kinases and inhibits HCO-3 absorption via distinct pathways in thick ascending limb

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12 December 2020

Targeted disruption of the PDZK1 gene by homologous recombination

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12 December 2020

NHERF-1 uniquely transduces the cAMP signals that inhibit sodium-hydrogen exchange in mouse renal apical membranes

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12 December 2020

Intestinal ion transport and the pathophysiology of diarrhea

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12 December 2020

PDZK1: I. a major scaffolder in brush borders of proximal tubular cells

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12 December 2020

PDZK1: II. an anchoring site for the PKA-binding protein D-AKAP2 in renal proximal tubular cells

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12 December 2020

Activation of AMP-activated protein kinase reduces cAMP-mediated epithelial chloride secretion

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12 December 2020

Ca2+-dependent inhibition of NHE3 requires PKC alpha which binds to E3KARP to decrease surface NHE3 containing plasma membrane complexes

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12 December 2020

Gating of CFTR by the STAS domain of SLC26 transporters

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12 December 2020

The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation.

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12 December 2020

The role of NHERF and E3KARP in the cAMP-mediated inhibition of NHE3.

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12 December 2020

cAMP-induced phosphorylation and inhibition of Na(+)/H(+) exchanger 3 (NHE3) are dependent on the presence but not the phosphorylation of NHE regulatory factor

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12 December 2020

Pyk2 activation is integral to acid stimulation of sodium/hydrogen exchanger 3.

1 reference

12 December 2020

Molecular physiology of intestinal Na+/H+ exchange

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12 December 2020

The CFTR associated protein CAP70 interacts with the apical Cl-/HCO3- exchanger DRA in rabbit small intestinal mucosa.

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12 December 2020

Role of PDZK1 in membrane expression of renal brush border ion exchangers.

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12 December 2020

Regulation of sodium-proton exchanger isoform 3 (NHE3) by PKA and exchange protein directly activated by cAMP (EPAC).

1 reference

12 December 2020

Regulation of drug transporters by PDZ adaptor proteins and nuclear receptors

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12 December 2020

PDZK1 is required for maintaining hepatic scavenger receptor, class B, type I (SR-BI) steady state levels but not its surface localization or function

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12 December 2020

Membrane curvature alters the activation kinetics of the epithelial Na+/H+ exchanger, NHE3.

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12 December 2020

Down regulation of small intestinal ion transport in PDZK1- (CAP70/NHERF3) deficient mice

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12 December 2020

Targeted Disruption of the PDZK1 Gene in Mice Causes Tissue-specific Depletion of the High Density Lipoprotein Receptor Scavenger Receptor Class B Type I and Altered Lipoprotein Metabolism

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12 December 2020

NHERF associations with sodium-hydrogen exchanger isoform 3 (NHE3) and ezrin are essential for cAMP-mediated phosphorylation and inhibition of NHE3

1 reference

12 December 2020

Acid incubation causes exocytic insertion of NHE3 in OKP cells

1 reference

12 December 2020

Signal complex regulation of renal transport proteins: NHERF and regulation of NHE3 by PKA.

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12 December 2020

Luminal osmolarity downregulates gene expression of Na+/H+ exchanger (NHE3) in rat colon mucosa

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12 December 2020

Coordination of pancreatic HCO3- secretion by protein-protein interaction between membrane transporters

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12 December 2020

Apical Na+/H+ exchange near the base of mouse colonic crypts

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12 December 2020

Ca(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and endocytosis

1 reference

12 December 2020

Role of c-SRC and ERK in acid-induced activation of NHE3

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12 December 2020

Acid-base effects on intestinal Na(+) absorption and vesicular trafficking

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12 December 2020

The down regulated in adenoma (dra) gene product binds to the second PDZ domain of the NHE3 kinase A regulatory protein (E3KARP), potentially linking intestinal Cl-/HCO3- exchange to Na+/H+ exchange

1 reference

12 December 2020

cAMP-mediated regulation of murine intestinal/pancreatic Na+/HCO3- cotransporter subtype pNBC1.

1 reference

12 December 2020

pH regulation in single glomerular mesangial cells. II. Na+-dependent and -independent Cl(-)-HCO3- exchangers

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12 December 2020

10.1113/JPHYSIOL.2007.131722

Identifiers

DOI

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