Association studies of genetic polymorphisms in central obesity: a critical review (Q79087999)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14513062%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

review article

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title

Association studies of genetic polymorphisms in central obesity: a critical review (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14513062%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

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R. Rosmond

1

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15 March 2024

language of work or name

English

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National Center for Biotechnology Information

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15 March 2024

publication date

1 October 2003

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full work available at URL

19 December 2019

http://www.nature.com/articles/0802397.pdf

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Portable Document Format

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http://www.nature.com/articles/0802397

15 March 2024

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International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity

15 March 2024

published in

27

10

1141–51

October 2003

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National Center for Biotechnology Information

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15 March 2024

volume

27

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19 December 2019

issue

10

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19 December 2019

page(s)

1141-1151

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19 December 2019

1 reference

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Genetic determinants of regional fat distribution

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A comprehensive review of genetic association studies

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The use of single nucleotide polymorphisms in the isolation of common disease genes

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Unbiased methods for population-based association studies

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Association study designs for complex diseases

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How many diseases does it take to map a gene with SNPs?

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Searching for genetic determinants in the new millennium

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Evolving Methods in Genetic Epidemiology. II. Genetic Linkage from an Epidemiologic Perspective

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At the interfaces of epidemiology, genetics and genomics

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Epidemiological methods for studying genes and environmental factors in complex diseases

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The human obesity gene map: the 2001 update

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A polymorphism in the human agouti-related protein is associated with late-onset obesity

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A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome

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Beta2-adrenoceptor gene polymorphism, body weight, and physical activity

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Impact of polymorphisms of the human β 2 -adrenoceptor gene on obesity in a French population

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Polymorphisms of the beta2-adrenergic receptor gene (ADRB2) in relation to cardiovascular risk factors in men.

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Interactions among the glucocorticoid receptor, lipoprotein lipase and adrenergic receptor genes and abdominal fat in the Québec Family Study

1 reference

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7 January 2021

Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns.

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7 January 2021

The beta 3-adrenergic receptor gene Trp64Arg mutation is overrepresented in obese women. Effects on weight, BMI, abdominal fat, blood pressure, and reproductive history in an elderly Australian population

1 reference

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7 January 2021

Beta 3-adrenergic-receptor polymorphism: a genetic marker for visceral fat obesity and the insulin resistance syndrome

1 reference

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7 January 2021

Effects of Trp64Arg Mutation in the β3-Adrenergic Receptor Gene on Weight Loss, Body Fat Distribution, Glycemic Control, and Insulin Resistance in Obese Type 2 Diabetic Patients

1 reference

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7 January 2021

A mutation of the b3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride

1 reference

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7 January 2021

A paired sibling analysis of the beta-3 adrenergic receptor and obesity in Mexican Americans

1 reference

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7 January 2021

Relationship of the Trp64Arg polymorphism of the beta3-adrenoceptor gene to central adiposity and high blood pressure: interaction with age. Cross-sectional and longitudinal findings of the Olivetti Prospective Heart Study.

1 reference

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7 January 2021

Human evidence that the apolipoprotein a-II gene is implicated in visceral fat accumulation and metabolism of triglyceride-rich lipoproteins

1 reference

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7 January 2021

ApoB-100 gene EcoRI polymorphism. Relations to plasma lipoprotein changes associated with abdominal visceral obesity

1 reference

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7 January 2021

Polymorphism in the 3' untranslated region of MTG8 is associated with obesity in Pima Indian males

1 reference

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7 January 2021

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7 January 2021

Vitamin D and estrogen receptor gene polymorphisms in type 2 diabetes mellitus and in android type obesity

1 reference

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7 January 2021

Association between Ala54Thr substitution of the fatty acid-binding protein 2 gene with insulin resistance and intra-abdominal fat thickness in Japanese men

1 reference

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7 January 2021

5' flanking variants of resistin are associated with obesity

1 reference

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7 January 2021

Allelic variants in the GABA(A)alpha6 receptor subunit gene (GABRA6) is associated with abdominal obesity and cortisol secretion

1 reference

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7 January 2021

Gly40Ser polymorphism of the glucagon receptor gene is associated with central adiposity in men.

1 reference

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7 January 2021

Association studies between microsatellite markers within the gene encoding human 11beta-hydroxysteroid dehydrogenase type 1 and body mass index, waist to hip ratio, and glucocorticoid metabolism

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7 January 2021

5-HT2A receptor gene promoter polymorphism in relation to abdominal obesity and cortisol

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7 January 2021

Central obesity and hyperinsulinaemia in women are associated with polymorphism in the 5' flanking region of the human insulin gene

1 reference

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7 January 2021

Polymorphisms in the leptin receptor gene, body composition and fat distribution in overweight and obese women

1 reference

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7 January 2021

Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil

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The putative role of the hormone-sensitive lipase gene in the pathogenesis of Type II diabetes mellitus and abdominal obesity

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7 January 2021

A common hormone-sensitive lipase i6 gene polymorphism is associated with decreased human adipocyte lipolytic function

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Genetic variation in LMNA modulates plasma leptin and indices of obesity in aboriginal Canadians

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A missense mutation in the human melanocortin-4 receptor gene in relation to abdominal obesity and salivary cortisol

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Sequence variation within the neuropeptide Y gene and obesity in Mexican Americans

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7 January 2021

Abdominal visceral fat is associated with a BclI restriction fragment length polymorphism at the glucocorticoid receptor gene locus

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7 January 2021

A glucocorticoid receptor gene marker is associated with abdominal obesity, leptin, and dysregulation of the hypothalamic-pituitary-adrenal axis

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Impact of the Peroxisome Proliferator Activated Receptor γ2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus

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7 January 2021

Interactions between variants in the beta3-adrenergic receptor and peroxisome proliferator-activated receptor-gamma2 genes and obesity

1 reference

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7 January 2021

Peroxisome proliferator-activated receptor-gamma coactivator-1 gene locus: associations with obesity indices in middle-aged women

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Role of tumor necrosis factor-alpha gene locus in obesity and obesity-associated hypertension in French Canadians

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7 January 2021

Association of the TNF-alpha -308 G/A promoter polymorphism with insulin resistance in obesity

1 reference

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Polymorphism of the tumor necrosis factor-alpha receptor 2 gene is associated with obesity, leptin levels, and insulin resistance in young subjects and diet-treated type 2 diabetic patients

1 reference

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7 January 2021

Associations between uncoupling protein 2, body composition, and resting energy expenditure in lean and obese African American, white, and Asian children

1 reference

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7 January 2021

Evidence that single nucleotide polymorphism in the uncoupling protein 3 (UCP3) gene influences fat distribution in women of European and Asian origin.

1 reference

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Genetic dissection of complex traits

1 reference

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The sympathetic nervous system and obesity: role in aetiology and treatment

1 reference

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7 January 2021

The peripheral sympathetic nervous system in human obesity.

1 reference

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7 January 2021

Sympathetic neural activation in visceral obesity

1 reference

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7 January 2021

Mutations in the gene encoding for the beta 2-adrenergic receptor in normal and asthmatic subjects

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7 January 2021

Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function

1 reference

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7 January 2021

The different effects of a Gln27Glu beta 2-adrenoceptor gene polymorphism on obesity in males and in females

1 reference

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7 January 2021

The Gln27Glu beta2-adrenergic receptor variant is associated with obesity due to subcutaneous fat accumulation in Japanese men

1 reference

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7 January 2021

Gln27Glu and Arg16Gly polymorphisms of the beta2-adrenergic receptor gene are not associated with obesity in Japanese men

1 reference

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7 January 2021

Significance of beta2-adrenergic receptor gene polymorphism in obesity and type 2 diabetes mellitus in Korean subjects

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Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β3-Adrenergic–Receptor Gene

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Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

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7 January 2021

The Trp64Arg mutation of the beta3 adrenergic receptor gene has no effect on obesity phenotypes in the Québec Family Study and Swedish Obese Subjects cohorts

1 reference

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7 January 2021

Trp64Arg substitution in the β3-adrenergic receptor does not relate to body weight in healthy, premenopausal women

1 reference

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7 January 2021

The Trp64Arg Polymorphism of the 3-Adrenergic Receptor Gene: Lack of association with NIDDM and features of insulin resistance syndrome

1 reference

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Absence of association between genetic variation of the beta 3-adrenergic receptor and metabolic phenotypes in Oji-Cree

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7 January 2021

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Pharmacological characterization of a recently described human beta 3-adrenergic receptor mutant

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The Biochemical Effect of the Naturally Occurring Trp644→Arg Mutation on Human β3‐Adrenoceptor Activity

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Predictors of coronary heart disease and death in NIDDM: The Diabetes Intervention Study experience

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Polymorphism of the human beta3-adrenoceptor gene forms a well-conserved haplotype that is associated with moderate obesity and altered receptor function

1 reference

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7 January 2021

Trp64Arg mutation of beta3-adrenoceptor gene deteriorates lipolysis induced by beta3-adrenoceptor agonist in human omental adipocytes.

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7 January 2021

Leptin and the regulation of body weight in mammals

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The hypothalamic leptin receptor in humans: identification of incidental sequence polymorphisms and absence of the db/db mouse and fa/fa rat mutations

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7 January 2021

Human leptin receptor gene in obese Japanese subjects: evidence against either obesity-causing mutations or association of sequence variants with obesity

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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

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Thrifty genes and human obesity. Are we chasing ghosts?

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A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference

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The glucocorticoid receptor gene and its association to metabolic syndrome

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Tsp509I polymorphism in exon 2 of the glucocorticoid receptor gene in relation to obesity and cortisol secretion: cohort study

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7 January 2021

The Asn363Ser variant of the glucocorticoid receptor gene is not associated with obesity or weight gain in Danish men

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7 January 2021

Differential Hormone-Dependent Transcriptional Activation and -Repression by Naturally Occurring Human Glucocorticoid Receptor Variants

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7 January 2021

A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels

1 reference

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7 January 2021

Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product

1 reference

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7 January 2021

Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation

1 reference

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7 January 2021

The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription.

1 reference

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7 January 2021

Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians

1 reference

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7 January 2021

Tumor necrosis factor-alpha-238 and -308 polymorphisms do not associated with traits related to obesity and insulin resistance

1 reference

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7 January 2021

Mechanisms of TNF-alpha-induced insulin resistance

1 reference

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7 January 2021

Excessive fat accumulation is associated with the TNFα -308 G/A promoter polymorphism in women but not in men

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7 January 2021

Selected methodological issues in meiotic mapping of obesity genes in humans: issues of power and efficiency

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7 January 2021

Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations

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Candidate gene case-control association studies: advantages and potential pitfalls

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7 January 2021

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7 January 2021

Fetal and early life growth and body mass index from birth to early adulthood in 1958 British cohort: longitudinal study

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7 January 2021

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7 January 2021

Liver cirrhosis is risk factor for pyogenic liver abscesses

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7 January 2021

Apolipoprotein E polymorphism and lipid levels differ by gender and family history of diabetes: the Rancho Bernardo Study

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15 March 2024

Identifiers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14513062%20AND%20SRC:MED&resulttype=core&format=json

19 December 2019

1 reference