Managing and manipulating carbocations in biology: terpenoid cyclase structure and mechanism (Q77892154)

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9 December 2019

review article

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title

Managing and manipulating carbocations in biology: terpenoid cyclase structure and mechanism (English)

1 reference

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9 December 2019

author name string

C A Lesburg

1

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9 December 2019

J M Caruthers

2

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9 December 2019

C M Paschall

3

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9 December 2019

D W Christianson

4

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9 December 2019

publication date

1 December 1998

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Current Opinion in Structural Biology

9 December 2019

published in

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9 December 2019

volume

8

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9 December 2019

issue

6

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9 December 2019

page(s)

695-703

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Enzymatic cyclization of squalene and oxidosqualene to sterols and triterpenes

9 December 2019

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Crystal Structure of Pentalenene Synthase: Mechanistic Insights on Terpenoid Cyclization Reactions in Biology

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Pentalenene synthase. Purification, molecular cloning, sequencing, and high-level expression in Escherichia coli of a terpenoid cyclase from Streptomyces UC5319

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7 January 2021

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Trichodiene synthase. Probing the role of the highly conserved aspartate-rich region by site-directed mutagenesis.

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Identifying functional domains within terpene cyclases using a domain-swapping strategy

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Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of delta-selinene synthase and gamma-humulene synthase

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7 January 2021

Isoprenoid biosynthesis: manifold chemistry catalyzed by similar enzymes

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7 January 2021

Mechanism of taxadiene synthase, a diterpene cyclase that catalyzes the first step of taxol biosynthesis in Pacific yew

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7 January 2021

Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp

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7 January 2021

Structure and Function of a Squalene Cyclase

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7 January 2021

Site-directed mutagenesis of putative active-site residues in squalene-hopene cyclase

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7 January 2021

Identification of the active site of vertebrate oxidosqualene cyclase

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7 January 2021

Methodology for the Preparation of Pure RecombinantS. cerevisiaeLanosterol Synthase Using a Baculovirus Expression System. Evidence That Oxirane Cleavage and A-Ring Formation Are Concerted in the Biosynthesis of Lanosterol from 2,3-Oxidosqualene

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7 January 2021

Studies on the Substrate Binding Segments and Catalytic Action of Lanosterol Synthase. Affinity Labeling with Carbocations Derived from Mechanism-Based Analogs of 2,3-Oxidosqualene and Site-Directed Mutagenesis Probes

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7 January 2021