Cleavage site mutants of the subtype B insulin receptor are uncleaved and fully functional (Q73317109)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9140084%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Cleavage site mutants of the subtype B insulin receptor are uncleaved and fully functional (English)

1 reference

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3 November 2019

author name string

C Auzan

1

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3 November 2019

A Debant

2

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3 November 2019

B Rossi

3

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3 November 2019

E Clauser

4

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3 November 2019

publication date

1 April 1997

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Molecular and Cellular Endocrinology

3 November 2019

published in

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3 November 2019

volume

128

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3 November 2019

issue

1-2

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3 November 2019

page(s)

129-137

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3 November 2019

1 reference

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Growth factor receptor tyrosine kinases

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The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

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Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

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Insulin-resistant diabetes due to a point mutation that prevents insulin proreceptor processing

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Binding specificity and intramolecular signal transmission of uncleaved insulin proreceptor in transformed lymphocytes from a patient with extreme insulin resistance.

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Insulin Resistance by Uncleaved Insulin Proreceptor: Emergence of Binding Site by Trypsin

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Insulin-stimulated phosphorylation of the insulin receptor precursor

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Insulin binds to and promotes the phosphorylation of a Mr 210 000 component of its receptor in detergent extracts of rat liver microsomes

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7 January 2021

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

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Insulin and rabbit anti-insulin receptor antibodies stimulate additively the intrinsic receptor kinase activity.

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Signal transduction by receptors with tyrosine kinase activity

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Insulin resistance by unprocessed insulin proreceptors point mutation at the cleavage site

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7 January 2021

Alternative splicing of human insulin receptor messenger RNA.

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Different ligand affinities of the two human insulin receptor splice variants are reflected in parallel changes in sensitivity for insulin action

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Functional properties of two naturally occurring isoforms of the human insulin receptor in Chinese hamster ovary cells

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Defective processing of insulin-receptor precursor in cultured lymphocytes from a patient with extreme insulin resistance

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7 January 2021

Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors

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7 January 2021

10.1016/S0303-7207(97)04024-0

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9140084%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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