CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling (Q73035416)

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31 October 2019

title

CD4+ T cell survival is not directly linked to self-MHC-induced TCR signaling (English)

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31 October 2019

author name string

Dorfman JR

1

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31 October 2019

Stefanová I

2

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31 October 2019

Yasutomo K

3

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31 October 2019

Germain RN

4

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31 October 2019

publication date

1 October 2000

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31 October 2019

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31 October 2019

volume

1

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31 October 2019

issue

4

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31 October 2019

page(s)

329-335

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Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

31 October 2019

cites work

1 reference

7 January 2021

Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes

1 reference

7 January 2021

Preselection thymocytes are more sensitive to T cell receptor stimulation than mature T cells

1 reference

7 January 2021

Divergent changes in the sensitivity of maturing T cells to structurally related ligands underlies formation of a useful T cell repertoire

1 reference

7 January 2021

MHC Class II Molecules Are Not Required for Survival of Newly Generated CD4+ T Cells, but Affect Their Long-Term Life Span

1 reference

7 January 2021

Differential requirements for survival and proliferation of CD8 naïve or memory T cells

1 reference

7 January 2021

Targeted Complementation of MHC Class II Deficiency by Intrathymic Delivery of Recombinant Adenoviruses

1 reference

7 January 2021

Survival of Mature CD4 T Lymphocytes Is Dependent on Major Histocompatibility Complex Class II–expressing Dendritic Cells

1 reference

7 January 2021

Peripheral T Cell Survival Requires Continual Ligation of the T Cell Receptor to Major Histocompatibility Complex–Encoded Molecules

1 reference

7 January 2021

Long-term T cell memory requires the surface expression of self-peptide/major histocompatibility complex molecules

1 reference

7 January 2021

Designing and maintaining the mature TCR repertoire: the continuum of self-peptide:self-MHC complex recognition

1 reference

7 January 2021

Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules

1 reference

7 January 2021

TCR-MHC class II interaction is required for peripheral expansion of CD4 cells in a T cell-deficient host

1 reference

7 January 2021

Naïve cytotoxic T lymphocytes spontaneously acquire effector function in lymphocytopenic recipients: A pitfall for T cell memory studies?

1 reference

7 January 2021

CD4+ T cell division in irradiated mice requires peptides distinct from those responsible for thymic selection

1 reference

7 January 2021

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

1 reference

7 January 2021

Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts

1 reference

7 January 2021

Homeostatic expansion and phenotypic conversion of naïve T cells in response to self peptide/MHC ligands

1 reference

7 January 2021

Persistence of memory CD8 T cells in MHC class I-deficient mice

1 reference

7 January 2021

Mature CD4+ T Cells Perceive a Positively Selecting Class II MHC/Peptide Complex in the Periphery

1 reference

7 January 2021

Constitutive Tyrosine Phosphorylation of the T-Cell Receptor (TCR) ζ Subunit: Regulation of TCR-Associated Protein Tyrosine Kinase Activity by TCR ζ

1 reference

7 January 2021

ZAP-70 is constitutively associated with tyrosine-phosphorylated TCR ζ in murine thymocytes and lymph node T cells

1 reference

7 January 2021

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

1 reference

7 January 2021

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

1 reference

7 January 2021

1 reference

7 January 2021

Peripheral selection of the T cell repertoire

1 reference

7 January 2021

Memory/effector T cells in TCR transgenic mice develop via recognition of enteric antigens by a second, endogenous TCR.

1 reference

7 January 2021

Crippling of CD3-ζ ITAMs Does Not Impair T Cell Receptor Signaling

1 reference

7 January 2021

Role of the multiple T cell receptor (TCR)-zeta chain signaling motifs in selection of the T cell repertoire

1 reference

7 January 2021

Restoration of T-cell homeostasis after T-cell depletion

1 reference

7 January 2021

Positive selection of T cells: rescue from programmed cell death and differentiation require continual engagement of the T cell receptor.

1 reference

7 January 2021

Two separable T cell receptor signals reconstitute positive selection of CD4 lineage T cells in vivo

1 reference

7 January 2021

TCR signaling for initiation and completion of thymocyte positive selection has distinct requirements for ligand quality and presenting cell type.

1 reference

7 January 2021

Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway

1 reference

7 January 2021

H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection

1 reference

7 January 2021

Intrathymic signalling in immature CD4+ CD8+ thymocytes results in tyrosine phosphorylation of the T-cell receptor zeta chain

1 reference

7 January 2021

Selective events in T cell development

1 reference

7 January 2021

Disruption of the CD4–major histocompatibility complex class II interaction blocks the development of CD4+T cellsin vivo

1 reference

7 January 2021

MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8

1 reference

7 January 2021

Mice lacking MHC class II molecules

1 reference

7 January 2021

Survival and homeostatic proliferation of naive peripheral CD4+ T cells in the absence of self peptide:MHC complexes

1 reference

7 January 2021

Peripheral Selection of T Cell Repertoires: The Role of Continuous Thymus Output

1 reference

7 January 2021

Inactivation of misselected CD8 T cells by CD8 gene methylation and cell death

1 reference

7 January 2021

Differential reactivity of residual CD8+ T lymphocytes in TAP1 and beta 2-microglobulin mutant mice

1 reference

7 January 2021

Reactivity and specificity of CD8+ T cells in mice with defects in the MHC class I antigen-presenting pathway

1 reference

7 January 2021

Antiproliferative action of interferon-α requires components of T-cell-receptor signalling

1 reference

7 January 2021

Inhibition of interleukin 2 signaling and signal transducer and activator of transcription (STAT)5 activation during T cell receptor-mediated feedback inhibition of T cell expansion

1 reference

7 January 2021

Modulation of TCR signaling by beta1 integrins: role of the tyrosine phosphatase SHP-1.

1 reference

7 January 2021

The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation

1 reference

7 January 2021

Homeostasis of alpha beta TCR+ T cells.

1 reference

7 January 2021

Adaptive cellular interactions in the immune system: the tunable activation threshold and the significance of subthreshold responses

1 reference

7 January 2021

Partially phosphorylated T cell receptor zeta molecules can inhibit T cell activation

1 reference

7 January 2021

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.

1 reference

7 January 2021

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

1 reference

7 January 2021

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

7 January 2021

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

1 reference

7 January 2021

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1 reference

7 January 2021

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

1 reference

7 January 2021

The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

1 reference

7 January 2021

Identifiers

DOI

10.1038/79783

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11017105%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference