Characterization of non-inducible Tet repressor mutants suggests conformational changes necessary for induction (Q71727008)

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20 October 2019

title

Characterization of non-inducible Tet repressor mutants suggests conformational changes necessary for induction (English)

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20 October 2019

author name string

Müller G

1

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20 October 2019

Hecht B

2

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20 October 2019

Helbl V

3

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20 October 2019

Saenger W

5

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20 October 2019

publication date

1 August 1995

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Nature structural biology

20 October 2019

published in

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20 October 2019

volume

2

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20 October 2019

issue

8

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20 October 2019

page(s)

693-703

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Signal transduction schemes of bacteria

20 October 2019

cites work

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Crystal structure of the met repressor-operator complex at 2.8 A resolution reveals DNA recognition by beta-strands

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The solution structures of the trp repressor-operator DNA complex

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Kinetic and equilibrium characterization of the Tet repressor-tetracycline complex by fluorescence measurements. Evidence for divalent metal ion requirement and energy transfer

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Equilibrium and kinetic studies of Escherichia coli lac repressor-inducer interactions

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The general affinity of lac repressor for E. coli DNA: Implications for gene regulation in procaryotes and eucaryotes

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Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 A resolution

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Three-dimensional crystal structures of Escherichia coli met repressor with and without corepressor

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Structural analysis of the operator binding domain of Tn10-encoded Tet repressor: a time-resolved fluorescence and anisotropy study

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Refined solution structures of the Escherichia coli trp holo- and aporepressor

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The crystal structure of trp aporepressor at 1.8 A shows how binding tryptophan enhances DNA affinity

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Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance

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The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance

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Saturation mutagenesis of the Tn10-encoded tet operator O1. Identification of base-pairs involved in Tet repressor recognition

31 March 2020

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Tet repressor-tet operator contacts probed by operator DNA-modification interference studies

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Quantitative analysis of Tn10 Tet repressor binding to a complete set of tet operator mutants

31 March 2020

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Tet repressor binding induced curvature of tet operator DNA

31 March 2020

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Contacts between Tet repressor and tet operator revealed by new recognition specificities of single amino acid replacement mutants

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Proximity probing of Tet repressor to tet operator by dimethylsulfate reveals protected and accessible functions for each recognized base-pair in the major groove.

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Mutations in the Tn10 tet repressor that interfere with induction. Location of the tetracycline-binding domain.

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Noninducible Tet repressor mutations map from the operator binding motif to the C terminus

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Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as "spacers" which do not require a specific sequence.

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Packing of α-helices: Geometrical constraints and contact areas

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Lac repressor-operator interaction. V. Characterization of super- and pseudo-wild-type repressors

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Structural requirements of tetracycline-Tet repressor interaction: determination of equilibrium binding constants for tetracycline analogs with the Tet repressor

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Determination of the equilibrium association constant between tet repressor and tetracycline at limiting Mg2+ concentrations: A generally applicable method for effector-dependent high-affinity complexes

31 March 2020

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TET repressor.tet operator complex formation induces conformational changes in the tet operator DNA.

31 March 2020

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The allosteric transition of glycogen phosphorylase

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Proximity mapping of the Tet repressor-tetracycline-Fe2+ complex by hydrogen peroxide mediated protein cleavage.

31 March 2020

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Mechanisms underlying expression of Tn10 encoded tetracycline resistance

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSB0895-693

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7552732%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

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