Comparison of intestinal permeabilities determined in multiple in vitro and in situ models: relationship to absorption in humans (Q71536582)

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19 October 2019

title

Comparison of intestinal permeabilities determined in multiple in vitro and in situ models: relationship to absorption in humans (English)

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19 October 2019

author name string

B H Stewart

1

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19 October 2019

O H Chan

2

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19 October 2019

R H Lu

3

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19 October 2019

E L Reyner

4

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19 October 2019

H L Schmid

5

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19 October 2019

H W Hamilton

6

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19 October 2019

B A Steinbaugh

7

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19 October 2019

M D Taylor

8

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19 October 2019

publication date

1 May 1995

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19 October 2019

published in

Pharmaceutical Research

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19 October 2019

volume

12

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19 October 2019

issue

5

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19 October 2019

page(s)

693-699

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In Vitro Drug Absorption Models. II. Salicylate, Cefoxitin, α-Methyldopa and Theophylline Uptake in Cells and Rings: Correlation with In Vivo Bioavailability

19 October 2019

cites work

1 reference

12 December 2020

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

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12 December 2020

Evaluation of physicochemical parameters important to the oral bioavailability of peptide-like compounds: implications for the synthesis of renin inhibitors

1 reference

12 December 2020

Intestinal absorption of peptides

1 reference

12 December 2020

In vitro drug absorption models. I. Brush border membrane vesicles, isolated mucosal cells and everted intestinal rings: characterization and salicylate accumulation

1 reference

12 December 2020

A correlation between the permeability characteristics of a series of peptides using an in vitro cell culture model (Caco-2) and those using an in situ perfused rat ileum model of the intestinal mucosa

1 reference

12 December 2020

Estimating human oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds.

1 reference

12 December 2020

A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of the lack of proportionality between increasing dose and drug levels in plasma

1 reference

12 December 2020

In vitro studies of intestinal drug absorption. Determination of partition and distribution coefficients with brush border membrane vesicles

1 reference

12 December 2020

Uptake of prodrugs by rat intestinal mucosal cells: mechanism and pharmaceutical implications

1 reference

12 December 2020

Selective paracellular permeability in two models of intestinal absorption: cultured monolayers of human intestinal epithelial cells and rat intestinal segments

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12 December 2020

The gradient of mucosal surface area in the small intestine of the rat.

1 reference

12 December 2020

In vitro/in vivo models for peptide oral absorption: comparison of Caco-2 cell permeability with rat intestinal absorption of renin inhibitory peptides

1 reference

12 December 2020

Determination of intrinsic membrane transport parameters from perfused intestine experiments: A boundary layer approach to estimating the aqueous and unbiased membrane permeabilities

1 reference

12 December 2020

Cell cultures as models for drug absorption across the intestinal mucosa

1 reference

12 December 2020

Multiple transport pathways for neutral amino acids in rabbit jejunal brush border vesicles

1 reference

12 December 2020

Influence of D-glucose-induced water absorption on rat jejunal uptake of two passively absorbed drugs.

1 reference

12 December 2020

Use of everted intestinal rings for in vitro examination of oral absorption potential

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12 December 2020

Identifiers

DOI

10.1023/A:1016207525186

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19 October 2019

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