lubiprostone (Q6695342)

Lubiprostone (English)

18 November 2016

tautomer of

lubiprostone (open form)

0 references

chemical formula

C₂₀H₃₂F₂O₅

1 reference

Lubiprostone (English)

18 November 2016

canonical SMILES

CCCCC(C1(CCC2C(O1)CC(=O)C2CCCCCCC(=O)O)O)(F)F

1 reference

Lubiprostone (English)

18 November 2016

isomeric SMILES

CCCCC(F)(F)[C@@]1(O)CC[C@H]2[C@@H](CC(=O)[C@@H]2CCCCCCC(O)=O)O1

1 reference

medical condition treated

14 February 2018

1 reference

14 February 2018

irritable bowel syndrome

1 reference

Drug Indications Extracted from FAERS

2 October 2018

constipation

1 reference

Drug Indications Extracted from FAERS

2 October 2018

30 January 2006

Food and Drug Administration

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/7662KG2R6K

2 November 2018

reference URL

http://www.accessdata.fda.gov/drugsatfda_docs/nda/2011/021908Orig1s008.pdf

physically interacts with

chloride voltage-gated channel 2

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4242

imported from Wikimedia project

17 August 2016

pregnancy category

US pregnancy category C

1 reference

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category E

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Lubiprostone

last update

25 April 2019

subject has role

chloride channel agonist

1 reference

Medical Subject Headings

15 March 2018

C66040

1 reference

InChI=1S/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/m1/s1

14 February 2018

Lubiprostone

0 references

Identifiers

InChI

1 reference

Lubiprostone (English)

18 November 2016

2 references

Lubiprostone (English)

18 November 2016

reason for deprecated rank

14 February 2018

applies to other chemical entity

intended subject of deprecated statement

lubiprostone (open form)

1 reference

https://commonchemistry.cas.org/detail?cas_rn=333963-40-9

14 February 2018

1 reference

31 December 2022

1 reference

Lubiprostone (English)

18 November 2016

2 references

Lubiprostone (English)

18 November 2016

reason for deprecated rank

ChEBI ID

34945

cannot be confirmed by other sources

1 reference

ChEBI release 2019-10-02

1 reference

LUBIPROSTONE (English)

18 November 2016

2 references

inferred from InChIKey

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

1 reference

1 reference

DTXSID80861338

1 reference

DSSTOX compound identifier

0 references

0 references

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.107.168

27 December 2018

ECHA Substance Infocard ID

Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)- (English)

quotation

CAS no.: 136790-76-6 (English)

100.107.168

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.107.168

20 December 2018

Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)- (English)

quotation

CAS no.: 136790-76-6 (English)

1 reference

Guide to Pharmacology Ligand ID

Lubiprostone (English)

publication date

17 November 2015

4242

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

4242

lubiprostone (English)

18 November 2016

Lubiprostone

0 references

MeSH tree code

D10.251.355.325.050.500

0 references

RxNorm ID

623033

1 reference

14 February 2018

1 reference

2 references

14 February 2018

MedlinePlus drug identifier

0 references

1 reference

lubiprostone (English)

18 November 2016

0 references

1 reference

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

Lubiprostone (English)

19 January 2016

0 references

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

UMLS CUI

C1684405

1 reference

lubiprostone (English)